DOI: 10.1126/science.167.3919.878. Metabolic Dependence of Fast Axoplasmic Transport in Nerve

Metabolic Dependence of Fast Axoplasmic Transport in Nerve

10.1126/science.167.3919.878

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Fast axoplasmic transport, shown in cat sciatic nerves by a crest of labeled activity after injection of the L7 ganglion with [ 3 H]-leucine or [ 3 H]-lysine, was stopped within 15 minutes after death of the animals by bleeding. If the sciatic nerves were removed from the animals and placed in a chamber supplied with oxygen at 38 degrees centigrade, fast transport was sustained. Transport was rapidly blocked in similar in vitro preparations when the nerves were kept in a nitrogen environment. Fast axoplasmic transport is closely dependent upon oxibdative metabolism.

Bibliography

Ochs, S., & Ranish, N. (1970). Metabolic Dependence of Fast Axoplasmic Transport in Nerve. Science, 167(3919), 878â879.

Authors 2

Sidney Ochs (first)
N. Ranish (additional)

References 12 Referenced 58

GERARD, R.W., The response of nerve to oxygen lack, AMERICAN JOURNAL OF PHYSIOLOGY 92: 498 (1930). (10.1152/ajplegacy.1930.92.2.498) / AMERICAN JOURNAL OF PHYSIOLOGY (1930)
GERARD, R.W., Nerve metabolism, PHYSIOLOGICAL REVIEWS 12: 469 (1932). (10.1152/physrev.1932.12.4.469) / PHYSIOLOGICAL REVIEWS (1932)
LEHMANN, J.E., AM J PHYSIOL 119: 111 (1937). (10.1152/ajplegacy.1937.119.1.111) / AM J PHYSIOL (1937)
MARUHASHI, J, EFFECT OF OXYGEN LACK ON SINGLE ISOLATED MAMMALIAN (RAT) NERVE FIBER, JOURNAL OF NEUROPHYSIOLOGY 30: 434 (1967). (10.1152/jn.1967.30.3.434) / JOURNAL OF NEUROPHYSIOLOGY (1967)
Ochs, S., Journal of Neurobiology 1: 247 (1969). (10.1002/neu.480010211) / Journal of Neurobiology (1969)
OCHS, S, FAST AND SLOW PHASES OF AXOPLASMIC FLOW IN VENTRAL ROOT NERVE FIBRES, JOURNAL OF NEUROCHEMISTRY 16: 845 (1969). (10.1111/j.1471-4159.1969.tb08972.x) / JOURNAL OF NEUROCHEMISTRY (1969)
OCHS, S, NEUROSCIENCES RESEARCH PROGRAM BULLETIN 5: 337 (1967). / NEUROSCIENCES RESEARCH PROGRAM BULLETIN (1967)
10.1126/science.163.3868.686
Ochs, S., Proceedings of the 2nd Meeting of the International Society of Neurochemistry: 305 (1969). / Proceedings of the 2nd Meeting of the International Society of Neurochemistry (1969)
SCHMITT, F.O., FIBROUS PROTEINS - NEURONAL ORGANELLES, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 60: 1092 (1968). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1968)
WRIGHT, E.B., A COMPARATIVE STUDY OF THE EFFECTS OF OXYGEN LACK ON PERIPHERAL NERVE, AMERICAN JOURNAL OF PHYSIOLOGY 147: 78 (1946). (10.1152/ajplegacy.1946.147.1.78) / AMERICAN JOURNAL OF PHYSIOLOGY (1946)
WRIGHT, E.B., THE EFFECTS OF ASPHYXIATION AND NARCOSIS ON PERIPHERAL NERVE POLARIZATION AND CONDUCTION, AMERICAN JOURNAL OF PHYSIOLOGY 148: 174 (1947). (10.1152/ajplegacy.1947.148.1.174) / AMERICAN JOURNAL OF PHYSIOLOGY (1947)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 8:56 a.m.)
Deposited	1 year, 7 months ago (Jan. 11, 2024, 10:03 a.m.)
Indexed	1 year, 5 months ago (March 5, 2024, 3:21 p.m.)
Issued	55 years, 6 months ago (Feb. 6, 1970)
Published	55 years, 6 months ago (Feb. 6, 1970)
Published Print	55 years, 6 months ago (Feb. 6, 1970)

Funders 0

None

BibTeX

@article{Ochs_1970, title={Metabolic Dependence of Fast Axoplasmic Transport in Nerve}, volume={167}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.167.3919.878}, DOI={10.1126/science.167.3919.878}, number={3919}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Ochs, Sidney and Ranish, N.}, year={1970}, month=feb, pages={878–879} }

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