DOI: 10.1126/science.163.3868.686. Fast Transport System of Materials in Mammalian Nerve Fibers

Fast Transport System of Materials in Mammalian Nerve Fibers

10.1126/science.163.3868.686

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

A fast transport system of materials is shown in cat sensory fibers of sciatic nerve. After injection of tritiated leucine into the lumbar seventh ganglia, the distribution of activity was measured in the sciatic nerves from 2 to 8 hours afterward. The distribution showed a crest of activity advancing down the fibers at a rate of approximately 410 millimeters per day. An intraaxonic locus of the activity was indicated by a block of the downflow induced by local freezing which causes the fibers to close off. Some of the activity in the nerve was due to free tritiated leucine, with most of it incorporated into polypeptide, soluble protein, and subcellular particulates.

Bibliography

Ochs, S., Sabri, M. I., & Johnsona, J. (1969). Fast Transport System of Materials in Mammalian Nerve Fibers. Science, 163(3868), 686â687.

Authors 3

S. Ochs (first)
M. I. Sabri (additional)
J. Johnsona (additional)

References 15 Referenced 98

BURDWOOD, W. O., JOURNAL OF CELL BIOLOGY 27: A115 (1965). / JOURNAL OF CELL BIOLOGY (1965)
DAHLSTROM, A, STUDIES ON TRANSPORT AND LIFE-SPAN OF AMINE STORAGE GRANULES IN A PERIPHERAL ADRENERGIC NEURON SYSTEM, ACTA PHYSIOLOGICA SCANDINAVICA 67: 278 (1966). (10.1111/j.1748-1716.1966.tb03313.x) / ACTA PHYSIOLOGICA SCANDINAVICA (1966)
KERKUT, G.A., TRANSPORT OF 14C-LABELLED MATERIAL FROM CNS-][-MUSCLE ALONG A NERVE TRUNK, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY 23: 729 (1967). (10.1016/0010-406X(67)90337-4) / COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY (1967)
Kidwai, A. M., Journal of Neurochemistry 16: 1105 (1969). (10.1111/j.1471-4159.1969.tb05955.x) / Journal of Neurochemistry (1969)
LASEK, R.J., BRAIN RES 7: 360 (1968). (10.1016/0006-8993(68)90003-6) / BRAIN RES (1968)
LUBINSKA, L, PROGRESS IN BRAIN RESEARCH 13: 1 (1964). (10.1016/S0079-6123(08)60139-9) / PROGRESS IN BRAIN RESEARCH (1964)
MCEWEN, B.S., FAST AND SLOW COMPONENTS IN AXONAL TRANSPORT OF PROTEIN, JOURNAL OF CELL BIOLOGY 38: 494 (1968). (10.1083/jcb.38.3.494) / JOURNAL OF CELL BIOLOGY (1968)
MIANI, N, ANALYSIS OF SOMATO-AXONAL MOVEMENT OF PHOSPHOLIPIDS IN VAGUS AND HYPOGLOSSAL NERVES, JOURNAL OF NEUROCHEMISTRY 10: 859 (1963). (10.1111/j.1471-4159.1963.tb11913.x) / JOURNAL OF NEUROCHEMISTRY (1963)
OCHS, S, AXOPLASMIC FLOW IN VENTRAL ROOT NERVE FIBERS OF CAT, EXPERIMENTAL NEUROLOGY 5: 349 (1962). (10.1016/0014-4886(62)90049-3) / EXPERIMENTAL NEUROLOGY (1962)
OCHS, S, FEDERATION PROCEEDINGS 27: 235 (1968). / FEDERATION PROCEEDINGS (1968)
Ochs, S., Journal of Neurochemistry 16: 845 (1969). (10.1111/j.1471-4159.1969.tb08972.x) / Journal of Neurochemistry (1969)
OCHS, S, PROTEIN INCORPORATION AND AXOPLASMIC FLOW IN MTONEURON FIBRES FOLLOWING INTRA-CORD INJECTION OF LABELLED LEUCINE, JOURNAL OF NEUROCHEMISTRY 14: 317 (1967). (10.1111/j.1471-4159.1967.tb09529.x) / JOURNAL OF NEUROCHEMISTRY (1967)
Ochs S. Macromolecules and Behavior (1966).
OCHS S NEUROSCIENCES RESEARCH PROGRAM BULLETIN 5 (1967).
SCHMITT, F.O., FIBROUS PROTEINS - NEURONAL ORGANELLES, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 60: 1092 (1968). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1968)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 8:14 a.m.)
Deposited	1 year, 7 months ago (Jan. 11, 2024, 5:36 a.m.)
Indexed	1 year, 7 months ago (Jan. 11, 2024, 7:05 p.m.)
Issued	56 years, 6 months ago (Feb. 14, 1969)
Published	56 years, 6 months ago (Feb. 14, 1969)
Published Print	56 years, 6 months ago (Feb. 14, 1969)

Funders 0

None

BibTeX

@article{Ochs_1969, title={Fast Transport System of Materials in Mammalian Nerve Fibers}, volume={163}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.163.3868.686}, DOI={10.1126/science.163.3868.686}, number={3868}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Ochs, S. and Sabri, M. I. and Johnsona, J.}, year={1969}, month=feb, pages={686–687} }

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