DOI: 10.1126/science.156.3777.961. Field Ion Microscopical Imaging of Biomolecules

Field Ion Microscopical Imaging of Biomolecules

10.1126/science.156.3777.961

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Specimen molecules are protected from field desorption by embedding them in a platinum matrix, with the use of electrolytic codeposition on tungsten tips. High-resolution helium ion images are obtained when the biomolecules are exposed during gradual removal of surface layers by controlled field evaporation. Structured images of individual molecules of coenzyme I and vitamin B12are seen.

Bibliography

MÃ¼ller, E. W., & Rendulic, K. D. (1967). Field Ion Microscopical Imaging of Biomolecules. Science, 156(3777), 961â963.

Authors 2

Erwin W. Müller (first)
Klaus D. Rendulic (additional)

References 16 Referenced 23

ABBOTT, R.C., DC FIELD DESORPTION OF MACROMOLECULES, JOURNAL OF CHEMICAL PHYSICS 43: 4533 (1965). (10.1063/1.1696736) / JOURNAL OF CHEMICAL PHYSICS (1965)
Blum W. Principles of Electroplating and Electroforming (1949).
Brillouin L. Horizons in Biochemnistry (1962).
EHRLICH, G, DIRECT OBSERVATION OF INDIVIDUAL ADATOMS - NITROGEN ON TUNGSTEN, JOURNAL OF CHEMICAL PHYSICS 36: 3233 (1962). (10.1063/1.1732451) / JOURNAL OF CHEMICAL PHYSICS (1962)
GURNEY, T, CONDENSATION OF TUNGSTEN ON TUNGSTEN IN ATOMIC DETAIL - OBSERVATION WITH FIELD-ION MICROSCOPE, JOURNAL OF CHEMICAL PHYSICS 42: 3939 (1965). (10.1063/1.1695864) / JOURNAL OF CHEMICAL PHYSICS (1965)
HOPKIN, N, Bright Platinum Plating, PLATINUM METALS REVIEW 4: 56 (1960). (10.1595/003214060X425658) / PLATINUM METALS REVIEW / Bright Platinum Plating (1960)
MCLANE, S.B., FIELD ION MICROSCOPY WITH EXTERNAL IMAGE INTENSIFIER, REVIEW OF SCIENTIFIC INSTRUMENTS 35: 1297 (1964). (10.1063/1.1718728) / REVIEW OF SCIENTIFIC INSTRUMENTS (1964)
Melmed A. J. ASTIA Tech Rep. AFOSR-TN58-646 (1958).
MOORE, AJW, STRUCTURE OF ATOMICALLY SMOOTH SPHERICAL SURFACES, JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS 23: 907 (1962). (10.1016/0022-3697(62)90148-8) / JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS (1962)
MULLER, E.W., ADVANCES IN ELECTRONICS AND ELECTRON PHYSICS 13: 83 (1960). (10.1016/S0065-2539(08)60210-3) / ADVANCES IN ELECTRONICS AND ELECTRON PHYSICS (1960)
10.1126/science.149.3684.591
MULSON, J.F., CORROSION OF TUNGSTEN AND IRIDIUM BY FIELD DESORPTION OF NITROGEN AND CARBON MONOXIDE, JOURNAL OF CHEMICAL PHYSICS 38: 2615 (1963). (10.1063/1.1733560) / JOURNAL OF CHEMICAL PHYSICS (1963)
RENDULIC, K.D., ATOMIC STRUCTURE OF PLATINUM CRYSTALS ELECTROLYTICALLY OVERGROWN ON FIELD-ION MICROSCOPE TIPS, JOURNAL OF APPLIED PHYSICS 38: 550 (1967). (10.1063/1.1709372) / JOURNAL OF APPLIED PHYSICS (1967)
Szent-Gyorgyi A. Introduction to Submolecular Biology (1960). (10.2307/3583585)
TSONG, T. T., APPLIED PHYSICS LETTERS 9: 7 (1966). (10.1063/1.1754605) / APPLIED PHYSICS LETTERS (1966)
TSONG, T.T., DOMAIN STRUCTURE OF ORDERED EQUIATOMIC PT-CO OBSERVED IN FIELD-ION MICROSCOPE, JOURNAL OF APPLIED PHYSICS 38: 545 (1967). (10.1063/1.1709371) / JOURNAL OF APPLIED PHYSICS (1967)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 7:08 a.m.)
Deposited	1 year, 6 months ago (Feb. 6, 2024, 6:18 p.m.)
Indexed	1 year, 6 months ago (Feb. 6, 2024, 7:20 p.m.)
Issued	58 years, 3 months ago (May 19, 1967)
Published	58 years, 3 months ago (May 19, 1967)
Published Print	58 years, 3 months ago (May 19, 1967)

Funders 0

None

BibTeX

@article{M_ller_1967, title={Field Ion Microscopical Imaging of Biomolecules}, volume={156}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.156.3777.961}, DOI={10.1126/science.156.3777.961}, number={3777}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Müller, Erwin W. and Rendulic, Klaus D.}, year={1967}, month=may, pages={961–963} }

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