DOI: 10.1126/science.145.3633.709. Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

10.1126/science.145.3633.709

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

When two clonal lines of mouse fibroblasts, each containing a drug-resistant marker, are grown together for 4 days, hybrid cells can be detected by selective conditions. These hybrid cells are presumed to be the result of mating. By the same method evidence can be obtained which suggests that mating may be followed by segregation.

Bibliography

Littlefield, J. W. (1964). Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants. Science, 145(3633), 709â710.

Authors 1

John W. Littlefield (first)

References 9 Referenced 1,542

BARSKI, G, COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES 251: 1825 (1960). / COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES (1960)
Ephrussi, B., Approaches to the Genetic Analysis of Mammalian Cells: 81 (1962). / Approaches to the Genetic Analysis of Mammalian Cells (1962)
GERSHON, D, PROPERTIES OF A SOMATIC HYBRID BETWEEN MOUSE CELLS WITH DIFFERENT GENOTYPES, NATURE 198: 912 (1963). (10.1038/198912a0) / NATURE (1963)
KIT, S, DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE, EXPERIMENTAL CELL RESEARCH 31: 297 (1963). (10.1016/0014-4827(63)90007-7) / EXPERIMENTAL CELL RESEARCH (1963)
LITTLEFIELD, J. W., FEDERATION PROCEEDINGS 23: 169 (1964). / FEDERATION PROCEEDINGS (1964)
LITTLEFIELD, J.W., INOSINIC ACID PYROPHOSPHORYLASE ACTIVITY OF MOUSE FIBROBLASTS PARTIALLY RESISTANT TO 8-AZAGUANINE, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 50: 568 (1963). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1963)
LITTLEFIELD J.W. UNPUBLISHED MATERIAL.
PONTECORVO, G, GENETIC ANALYSIS BASED ON MITOTIC RECOMBINATION, ADVANCES IN GENETICS INCORPORATING MOLECULAR GENETIC MEDICINE 9: 71 (1958). / ADVANCES IN GENETICS INCORPORATING MOLECULAR GENETIC MEDICINE (1958)
SZYBALSKI, W, NATIONAL CANCER INSTITUTE MONOGRAPH 7: 75 (1962). / NATIONAL CANCER INSTITUTE MONOGRAPH (1962)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 5:47 a.m.)
Deposited	1 year, 7 months ago (Jan. 10, 2024, 9:12 p.m.)
Indexed	1 month, 2 weeks ago (July 14, 2025, 11:34 p.m.)
Issued	61 years ago (Aug. 14, 1964)
Published	61 years ago (Aug. 14, 1964)
Published Print	61 years ago (Aug. 14, 1964)

Funders 0

None

BibTeX

@article{Littlefield_1964, title={Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants}, volume={145}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.145.3633.709}, DOI={10.1126/science.145.3633.709}, number={3633}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Littlefield, John W.}, year={1964}, month=aug, pages={709–710} }

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