DOI: 10.1126/science.1373910. Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35

Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35

10.1126/science.1373910

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

The mammalian splicing factor SC35 is required for the first step in the splicing reaction and for spliceosome assembly. The cloning and characterization of a complementary DNA encoding this protein revealed that it is a member of a family of splicing factors that includes mammalian SF2/ASF. This family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal serine-arginine-rich (SR) domain. A search of the DNA sequence database revealed that the thymus-specific exon (E T ) of the c- myb proto-oncogene is encoded on the antisense strand of the SC35 gene.

Bibliography

Fu, X.-D., & Maniatis, T. (1992). Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35. Science, 256(5056), 535â538.

Authors 2

Xiang-Dong Fu (first)
Tom Maniatis (additional)

References 33 Referenced 174

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Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 7:03 p.m.)
Deposited	1 year, 7 months ago (Jan. 10, 2024, 10:53 p.m.)
Indexed	1 month, 2 weeks ago (July 14, 2025, 11:14 p.m.)
Issued	33 years, 4 months ago (April 24, 1992)
Published	33 years, 4 months ago (April 24, 1992)
Published Print	33 years, 4 months ago (April 24, 1992)

Funders 0

None

BibTeX

@article{Fu_1992, title={Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35}, volume={256}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.1373910}, DOI={10.1126/science.1373910}, number={5056}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Fu, Xiang-Dong and Maniatis, Tom}, year={1992}, month=apr, pages={535–538} }

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