DOI: 10.1126/science.1188379. Soluble Protein of the Organic Matrix of Mollusk Shells: A Potential Template for Shell Formation

Soluble Protein of the Organic Matrix of Mollusk Shells: A Potential Template for Shell Formation

10.1126/science.1188379

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

A significant proportion of the soluble protein of the organic matrix of mollusk shells is composed of a repeating sequence of aspartic acid separated by either glycine or serine. This regularly spaced, negatively charged aspartic acid may function as a template upon which mineralization occurs.

Bibliography

Weiner, S., & Hood, L. (1975). Soluble Protein of the Organic Matrix of Mollusk Shells: A Potential Template for Shell Formation. Science, 190(4218), 987â989.

Authors 2

Stephen Weiner (first)
Leroy Hood (additional)

References 20 Referenced 313

BEVELANDER, G, AN ELECTRON MICROSCOPE STUDY OF FORMATION OF NACREOUS LAYER IN SHELL OF CERTAIN BIVALVE MOLLUSCS, CALCIFIED TISSUE RESEARCH 3: 84 (1969). (10.1007/BF02058648) / CALCIFIED TISSUE RESEARCH (1969)
Glimcher, M. J., Calcification in Biological Systems: 421 (1960). / Calcification in Biological Systems (1960)
GREGOIRE, C, ANNALES DE L'INSTITUT OCEANOGRAPHIQUE 31: 1 (1955). / ANNALES DE L'INSTITUT OCEANOGRAPHIQUE (1955)
HARE, P.E., CARNEGIE INSTITUTION OF WASHINGTON YEAR BOOK 64: 223 (1965). / CARNEGIE INSTITUTION OF WASHINGTON YEAR BOOK (1965)
10.1126/science.139.3551.216
HEDLEY, R.H., P ZOOL SOC LOND 130: 569 (1958). (10.1111/j.1096-3642.1958.tb00586.x) / P ZOOL SOC LOND (1958)
HOTTA, S, CHIKYU KAGAKU 23: 133 (1969). / CHIKYU KAGAKU (1969)
INGRAM, V.M., METHODS ENZYMOL 6: 225 (1963). / METHODS ENZYMOL (1963)
INGRAM, V.M., SEQUENCE METHODS, METHODS IN ENZYMOLOGY 6: 831 (1963). (10.1016/0076-6879(63)06258-3) / METHODS IN ENZYMOLOGY (1963)
JOPE, M, COMPREHENSIVE BIOCHEMISTRY 26: 749 (1971). / COMPREHENSIVE BIOCHEMISTRY (1971)
LEWIS, P.N., FOLDING OF POLYPEPTIDE CHAINS IN PROTEINS - PROPOSED MECHANISM FOR FOLDING, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 68: 2293 (1971). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1971)
LIPPMANN, F, SEDIMENTARY CARBONAT: 6 (1973). / SEDIMENTARY CARBONAT (1973)
NOCKOLDS, C.E., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 69: 581 (1972). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1972)
PARTRIDGE, S.M., PREFERENTIAL RELEASE OF ASPARTIC ACID DURING THE HYDROLYSIS OF PROTEINS, NATURE 165: 62 (1950). (10.1038/165062a0) / NATURE (1950)
PAULING, L, THE STRUCTURE OF PROTEINS - 2 HYDROGEN-BONDED HELICAL CONFIGURATIONS OF THE POLYPEPTIDE CHAIN, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 37: 205 (1951). / PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (1951)
10.1126/science.134.3482.841
SCHULTZ, J, SPECIFICITY OF CLEAVAGE OF PROTEINS BY DILUTE ACID .1. RELEASE OF ASPARTIC ACID FROM INSULIN, RIBONUCLEASE, AND GLUCAGON, BIOCHEMISTRY 1: 694 (1962). (10.1021/bi00910a024) / BIOCHEMISTRY (1962)
SIMKISS, K, COMP BIOCHEM PHYSIOL 16: 427 (1963). / COMP BIOCHEM PHYSIOL (1963)
TOWE, K.M., BIOMINERALISATION 4: 1 (1972). / BIOMINERALISATION (1972)
Wilbur, K. M., Physiology of Molluscs 1: 243 (1964). / Physiology of Molluscs (1964)

Dates

Type	When
Created	18 years, 10 months ago (Oct. 5, 2006, 11:11 a.m.)
Deposited	1 year, 7 months ago (Jan. 10, 2024, 4:47 a.m.)
Indexed	1 month, 1 week ago (July 11, 2025, 6:22 a.m.)
Issued	49 years, 8 months ago (Dec. 5, 1975)
Published	49 years, 8 months ago (Dec. 5, 1975)
Published Print	49 years, 8 months ago (Dec. 5, 1975)

Funders 0

None

BibTeX

@article{Weiner_1975, title={Soluble Protein of the Organic Matrix of Mollusk Shells: A Potential Template for Shell Formation}, volume={190}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.1188379}, DOI={10.1126/science.1188379}, number={4218}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Weiner, Stephen and Hood, Leroy}, year={1975}, month=dec, pages={987–989} }

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