DOI: 10.1126/science.1156409. Genetic Mapping in Human Disease

10.1126/science.1156409

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Genetic mapping provides a powerful approach to identify genes and biological processes underlying any trait influenced by inheritance, including human diseases. We discuss the intellectual foundations of genetic mapping of Mendelian and complex traits in humans, examine lessons emerging from linkage analysis of Mendelian diseases and genome-wide association studies of common diseases, and discuss questions and challenges that lie ahead.

Bibliography

Altshuler, D., Daly, M. J., & Lander, E. S. (2008). Genetic Mapping in Human Disease. Science, 322(5903), 881â888.

Authors 3

David Altshuler (first)
Mark J. Daly (additional)
Eric S. Lander (additional)

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Dates

Type	When
Created	16 years, 9 months ago (Nov. 6, 2008, 5:58 p.m.)
Deposited	1 year, 7 months ago (Jan. 10, 2024, 4:48 a.m.)
Indexed	50 minutes ago (Aug. 28, 2025, 10:47 p.m.)
Issued	16 years, 9 months ago (Nov. 7, 2008)
Published	16 years, 9 months ago (Nov. 7, 2008)
Published Print	16 years, 9 months ago (Nov. 7, 2008)

Funders 0

None

BibTeX

@article{Altshuler_2008, title={Genetic Mapping in Human Disease}, volume={322}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.1156409}, DOI={10.1126/science.1156409}, number={5903}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Altshuler, David and Daly, Mark J. and Lander, Eric S.}, year={2008}, month=nov, pages={881–888} }

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