DOI: 10.1126/science.1135795. Organic Glasses with Exceptional Thermodynamic and Kinetic Stability

Organic Glasses with Exceptional Thermodynamic and Kinetic Stability

10.1126/science.1135795

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Vapor deposition has been used to create glassy materials with extraordinary thermodynamic and kinetic stability and high density. For glasses prepared from indomethacin or 1,3-bis-(1-naphthyl)-5-(2-naphthyl)benzene, stability is optimized when deposition occurs on substrates at a temperature of 50 K below the conventional glass transition temperature. We attribute the substantial improvement in thermodynamic and kinetic properties to enhanced mobility within a few nanometers of the glass surface during deposition. This technique provides an efficient means of producing glassy materials that are low on the energy landscape and could affect technologies such as amorphous pharmaceuticals.

Bibliography

Swallen, S. F., Kearns, K. L., Mapes, M. K., Kim, Y. S., McMahon, R. J., Ediger, M. D., Wu, T., Yu, L., & Satija, S. (2007). Organic Glasses with Exceptional Thermodynamic and Kinetic Stability. Science, 315(5810), 353â356.

Authors 9

Stephen F. Swallen (first)
Kenneth L. Kearns (additional)
Marie K. Mapes (additional)
Yong Seol Kim (additional)
Robert J. McMahon (additional)
M. D. Ediger (additional)
Tian Wu (additional)
Lian Yu (additional)
Sushil Satija (additional)

References 29 Referenced 693

10.6028/jres.102.013
10.1038/35065704
10.1126/science.267.5206.1935
10.1021/jp953538d
10.1021/cr60135a002
10.1063/1.454295
10.1016/S0301-4622(03)00105-4
10.1103/PhysRevLett.93.235701
10.1103/PhysRevE.68.011505
10.1063/1.1599271
10.1063/1.1949211
10.1063/1.1728059
10.1021/jp9529329
10.1063/1.1712301
Materials and methods are available as supporting material on Science Online.
A. J. Kovacs, Fortschr. Hochpolym-Forsch.3, 394 (1963). / Fortschr. Hochpolym-Forsch. (1963)
10.1063/1.2191492
10.1063/1.1531587
10.1021/ja0291437
10.1038/nmat980
10.1103/PhysRevE.63.021501
10.1039/fd9949800219
10.1103/PhysRevLett.77.2002
10.1103/RevModPhys.75.237
10.1021/jp0260604
10.1021/j100005a035
10.1007/BF02648333
10.1103/PhysRevLett.92.025701
We acknowledge support for this work from NSF CHE-0605136 NSF-0412707 and USDA 2005-01303.

Dates

Type	When
Created	18 years, 8 months ago (Dec. 7, 2006, 8:59 p.m.)
Deposited	1 year, 7 months ago (Jan. 10, 2024, 4:58 a.m.)
Indexed	10 hours, 10 minutes ago (Aug. 22, 2025, 12:47 a.m.)
Issued	18 years, 7 months ago (Jan. 19, 2007)
Published	18 years, 7 months ago (Jan. 19, 2007)
Published Print	18 years, 7 months ago (Jan. 19, 2007)

Funders 0

None

BibTeX

@article{Swallen_2007, title={Organic Glasses with Exceptional Thermodynamic and Kinetic Stability}, volume={315}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.1135795}, DOI={10.1126/science.1135795}, number={5810}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Swallen, Stephen F. and Kearns, Kenneth L. and Mapes, Marie K. and Kim, Yong Seol and McMahon, Robert J. and Ediger, M. D. and Wu, Tian and Yu, Lian and Satija, Sushil}, year={2007}, month=jan, pages={353–356} }

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