DOI: 10.1126/science.1111041. Directed Assembly of Block Copolymer Blends into Nonregular Device-Oriented Structures

Directed Assembly of Block Copolymer Blends into Nonregular Device-Oriented Structures

10.1126/science.1111041

Crossref journal-article

American Association for the Advancement of Science (AAAS)

Science (221)

Abstract

Self-assembly is an effective strategy for the creation of periodic structures at the nanoscale. However, because microelectronic devices use free-form design principles, the insertion point of self-assembling materials into existing nanomanufacturing processes is unclear. We directed ternary blends of diblock copolymers and homopolymers that naturally form periodic arrays to assemble into nonregular device-oriented structures on chemically nanopatterned substrates. Redistribution of homopolymer facilitates the defect-free assembly in locations where the domain dimensions deviate substantially from those formed in the bulk. The ability to pattern nonregular structures using self-assembling materials creates new opportunities for nanoscale manufacturing.

Bibliography

Stoykovich, M. P., MuÌller, M., Kim, S. O., Solak, H. H., Edwards, E. W., de Pablo, J. J., & Nealey, P. F. (2005). Directed Assembly of Block Copolymer Blends into Nonregular Device-Oriented Structures. Science, 308(5727), 1442â1446.

Authors 7

Mark P. Stoykovich (first)
Marcus Müller (additional)
Sang Ouk Kim (additional)
Harun H. Solak (additional)
Erik W. Edwards (additional)
Juan J. de Pablo (additional)
Paul F. Nealey (additional)

References 36 Referenced 901

10.1126/science.276.5317.1401
10.1126/science.290.5499.2126
10.1038/414735a
R. R. Li et al., Appl. Phys. Lett.76, 1689 (2000). (10.1063/1.126137) / Appl. Phys. Lett. (2000)
10.1002/1521-4095(200108)13:15<1174::AID-ADMA1174>3.0.CO;2-Q
K. W. Guariniet al., in International Electron Devices Meeting Technical Digest (IEEE, Piscataway, NJ, 2003), pp. 541–544. / International Electron Devices Meeting Technical Digest (2003)
A. Urbas et al., Adv. Mater.12, 812 (2000). (10.1002/(SICI)1521-4095(200006)12:11<812::AID-ADMA812>3.0.CO;2-8) / Adv. Mater. (2000)
10.1063/1.1383805
10.1146/annurev.pc.41.100190.002521
10.1126/science.273.5277.931
10.1038/nature01775
10.1103/PhysRevLett.82.2602
X. M. Yang, R. D. Peters, P. F. Nealey, H. H. Solak, F. Cerrina, Macromolecules33, 9575 (2000). (10.1021/ma001326v) / Macromolecules (2000)
10.1002/1521-4095(200108)13:15<1152::AID-ADMA1152>3.0.CO;2-5
10.1038/nmat1211
D. Sundrani, S. B. Darling, S. J. Sibener, Nano. Lett.4, 273 (2004). (10.1021/nl035005j) / Nano. Lett. (2004)
D. E. Angelescu et al., Adv. Mater.16, 1736 (2004). (10.1002/adma.200400643) / Adv. Mater. (2004)
D. J. C. Herr in Future Fab International B. Dustrud Ed. (Montgomery Research Incorporated San Francisco CA 2005) issue 18 chap. 5.
J. Fujita, Y. Ohnishi, Y. Ochiai, S. Matsui, Appl. Phys. Lett.68, 1297 (1996). (10.1063/1.115958) / Appl. Phys. Lett. (1996)
K. E. Gonsalves, L. Merhari, H. Wu, Y. Hu, Adv. Mater.13, 703 (2001). (10.1002/1521-4095(200105)13:10<703::AID-ADMA703>3.0.CO;2-A) / Adv. Mater. (2001)
Q. Wang, S. K. Nath, P. F. Nealey, J. J. dePablo, J. Chem. Phys.112, 9996 (2000). (10.1063/1.481635) / J. Chem. Phys. (2000)
10.1002/adma.200400763
10.1126/science.275.5305.1458
Additional materials and methods information is available on Science Online.
H. H. Solak et al., Microelectron. Eng.67–68, 56 (2003). / Microelectron. Eng. (2003)
The lamellar spacing of the ternary block copolymer–homopolymer blends can be controlled over a wide range of values by changing the volume fraction of homopolymer. Little is known about their behavior in the form of thin films but previous studies of phase diagrams and morphology in the bulk ( 34 35 ) provide useful insights.
M. Müller, G. D. Smith, J. Polym. Sci. B43, 934 (2005). (10.1002/polb.20385) / J. Polym. Sci. B (2005)
G. H. Fredrickson, V. Ganesan, F. Drolet, Macromolecules35, 16 (2002). (10.1021/ma011515t) / Macromolecules (2002)
M. W. Matsen, F. S. Bates, Macromolecules29, 1091 (1996). (10.1021/ma951138i) / Macromolecules (1996)
A. Knoll et al., Nat. Mater.3, 886 (2004). (10.1038/nmat1258) / Nat. Mater. (2004)
S. P. Gido, E. L. Thomas, Macromolecules27, 6137 (1994). (10.1021/ma00099a031) / Macromolecules (1994)
E. Burgaz, S. P. Gido, Macromolecules33, 8739 (2000). (10.1021/ma000729s) / Macromolecules (2000)
D. Duque, K. Katsov, M. Schick, J. Chem. Phys.117, 10315 (2002). (10.1063/1.1519537) / J. Chem. Phys. (2002)
F. S. Bates et al., Phys. Rev. Lett.79, 849 (1997). (10.1103/PhysRevLett.79.849) / Phys. Rev. Lett. (1997)
D. Broseta, G. H. Fredrickson, J. Chem. Phys.93, 2927 (1990). (10.1063/1.458877) / J. Chem. Phys. (1990)
This research was supported by the Semiconductor Research Corporation (SRC) (2002-MJ-985) NSF through the Nanoscale Science and Engineering Center (DMR-0425880) and the Camille Dreyfus Teacher-Scholar Award. This work made use of the facilities and staff at the UW Center for Nanotechnology the Synchrotron Radiation Center at UW Madison (NSF DMR-0084402) and the Swiss Light Source at the Paul Scherrer Institute. The authors thank the John von Neumann-Institute for Computing Jülich Germany for central processing unit time on the IBM p690-cluster. M.P.S. acknowledges a research fellowship from the SRC Graduate Fellowship Program.

Dates

Type	When
Created	20 years, 2 months ago (June 2, 2005, 5:03 p.m.)
Deposited	1 year, 7 months ago (Jan. 9, 2024, 11:14 p.m.)
Indexed	3 days, 17 hours ago (Aug. 21, 2025, 12:26 p.m.)
Issued	20 years, 2 months ago (June 3, 2005)
Published	20 years, 2 months ago (June 3, 2005)
Published Print	20 years, 2 months ago (June 3, 2005)

Funders 0

None

BibTeX

@article{Stoykovich_2005, title={Directed Assembly of Block Copolymer Blends into Nonregular Device-Oriented Structures}, volume={308}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.1111041}, DOI={10.1126/science.1111041}, number={5727}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Stoykovich, Mark P. and Müller, Marcus and Kim, Sang Ouk and Solak, Harun H. and Edwards, Erik W. and de Pablo, Juan J. and Nealey, Paul F.}, year={2005}, month=jun, pages={1442–1446} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        21
      ]
    ],
    "date-time": "2025-08-21T16:26:54Z",
    "timestamp": 1755793614944
  },
  "reference-count": 36,
  "publisher": "American Association for the Advancement of Science (AAAS)",
  "issue": "5727",
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2005,
        6,
        3
      ]
    ]
  },
  "abstract": "<jats:p>Self-assembly is an effective strategy for the creation of periodic structures at the nanoscale. However, because microelectronic devices use free-form design principles, the insertion point of self-assembling materials into existing nanomanufacturing processes is unclear. We directed ternary blends of diblock copolymers and homopolymers that naturally form periodic arrays to assemble into nonregular device-oriented structures on chemically nanopatterned substrates. Redistribution of homopolymer facilitates the defect-free assembly in locations where the domain dimensions deviate substantially from those formed in the bulk. The ability to pattern nonregular structures using self-assembling materials creates new opportunities for nanoscale manufacturing.</jats:p>",
  "DOI": "10.1126/science.1111041",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        6,
        2
      ]
    ],
    "date-time": "2005-06-02T21:03:26Z",
    "timestamp": 1117746206000
  },
  "page": "1442-1446",
  "source": "Crossref",
  "is-referenced-by-count": 901,
  "title": "Directed Assembly of Block Copolymer Blends into Nonregular Device-Oriented Structures",
  "prefix": "10.1126",
  "volume": "308",
  "author": [
    {
      "given": "Mark P.",
      "family": "Stoykovich",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Chemical and Biological Engineering and Center for Nanotechnology, University of Wisconsin (UW), Madison, WI 53706, USA."
        },
        {
          "name": "Department of Physics, University of Wisconsin, Madison, WI 53706, USA."
        },
        {
          "name": "Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea."
        },
        {
          "name": "Laboratory for Micro- and Nanotechnology, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland."
        }
      ]
    },
    {
      "given": "Marcus",
      "family": "Mu\u0308ller",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemical and Biological Engineering and Center for Nanotechnology, University of Wisconsin (UW), Madison, WI 53706, USA."
        },
        {
          "name": "Department of Physics, University of Wisconsin, Madison, WI 53706, USA."
        },
        {
          "name": "Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea."
        },
        {
          "name": "Laboratory for Micro- and Nanotechnology, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland."
        }
      ]
    },
    {
      "given": "Sang Ouk",
      "family": "Kim",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemical and Biological Engineering and Center for Nanotechnology, University of Wisconsin (UW), Madison, WI 53706, USA."
        },
        {
          "name": "Department of Physics, University of Wisconsin, Madison, WI 53706, USA."
        },
        {
          "name": "Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea."
        },
        {
          "name": "Laboratory for Micro- and Nanotechnology, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland."
        }
      ]
    },
    {
      "given": "Harun H.",
      "family": "Solak",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemical and Biological Engineering and Center for Nanotechnology, University of Wisconsin (UW), Madison, WI 53706, USA."
        },
        {
          "name": "Department of Physics, University of Wisconsin, Madison, WI 53706, USA."
        },
        {
          "name": "Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea."
        },
        {
          "name": "Laboratory for Micro- and Nanotechnology, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland."
        }
      ]
    },
    {
      "given": "Erik W.",
      "family": "Edwards",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemical and Biological Engineering and Center for Nanotechnology, University of Wisconsin (UW), Madison, WI 53706, USA."
        },
        {
          "name": "Department of Physics, University of Wisconsin, Madison, WI 53706, USA."
        },
        {
          "name": "Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea."
        },
        {
          "name": "Laboratory for Micro- and Nanotechnology, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland."
        }
      ]
    },
    {
      "given": "Juan J.",
      "family": "de Pablo",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemical and Biological Engineering and Center for Nanotechnology, University of Wisconsin (UW), Madison, WI 53706, USA."
        },
        {
          "name": "Department of Physics, University of Wisconsin, Madison, WI 53706, USA."
        },
        {
          "name": "Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea."
        },
        {
          "name": "Laboratory for Micro- and Nanotechnology, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland."
        }
      ]
    },
    {
      "given": "Paul F.",
      "family": "Nealey",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Chemical and Biological Engineering and Center for Nanotechnology, University of Wisconsin (UW), Madison, WI 53706, USA."
        },
        {
          "name": "Department of Physics, University of Wisconsin, Madison, WI 53706, USA."
        },
        {
          "name": "Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea."
        },
        {
          "name": "Laboratory for Micro- and Nanotechnology, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland."
        }
      ]
    }
  ],
  "member": "221",
  "reference": [
    {
      "key": "e_1_3_1_2_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.276.5317.1401"
    },
    {
      "key": "e_1_3_1_3_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.290.5499.2126"
    },
    {
      "key": "e_1_3_1_4_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/414735a"
    },
    {
      "key": "e_1_3_1_5_2",
      "doi-asserted-by": "crossref",
      "first-page": "1689",
      "DOI": "10.1063/1.126137",
      "volume": "76",
      "year": "2000",
      "unstructured": "R. R. Li et al., Appl. Phys. Lett.76, 1689 (2000).",
      "journal-title": "Appl. Phys. Lett."
    },
    {
      "key": "e_1_3_1_6_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/1521-4095(200108)13:15<1174::AID-ADMA1174>3.0.CO;2-Q"
    },
    {
      "key": "e_1_3_1_7_2",
      "first-page": "541",
      "year": "2003",
      "unstructured": "K. W. Guariniet al., in International Electron Devices Meeting Technical Digest (IEEE, Piscataway, NJ, 2003), pp. 541\u2013544.",
      "journal-title": "International Electron Devices Meeting Technical Digest"
    },
    {
      "key": "e_1_3_1_8_2",
      "doi-asserted-by": "crossref",
      "first-page": "812",
      "DOI": "10.1002/(SICI)1521-4095(200006)12:11<812::AID-ADMA812>3.0.CO;2-8",
      "volume": "12",
      "year": "2000",
      "unstructured": "A. Urbas et al., Adv. Mater.12, 812 (2000).",
      "journal-title": "Adv. Mater."
    },
    {
      "key": "e_1_3_1_9_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1063/1.1383805"
    },
    {
      "key": "e_1_3_1_10_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1146/annurev.pc.41.100190.002521"
    },
    {
      "key": "e_1_3_1_11_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.273.5277.931"
    },
    {
      "key": "e_1_3_1_12_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/nature01775"
    },
    {
      "key": "e_1_3_1_13_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1103/PhysRevLett.82.2602"
    },
    {
      "key": "e_1_3_1_14_2",
      "doi-asserted-by": "crossref",
      "first-page": "9575",
      "DOI": "10.1021/ma001326v",
      "volume": "33",
      "year": "2000",
      "unstructured": "X. M. Yang, R. D. Peters, P. F. Nealey, H. H. Solak, F. Cerrina, Macromolecules33, 9575 (2000).",
      "journal-title": "Macromolecules"
    },
    {
      "key": "e_1_3_1_15_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/1521-4095(200108)13:15<1152::AID-ADMA1152>3.0.CO;2-5"
    },
    {
      "key": "e_1_3_1_16_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/nmat1211"
    },
    {
      "key": "e_1_3_1_17_2",
      "doi-asserted-by": "crossref",
      "first-page": "273",
      "DOI": "10.1021/nl035005j",
      "volume": "4",
      "year": "2004",
      "unstructured": "D. Sundrani, S. B. Darling, S. J. Sibener, Nano. Lett.4, 273 (2004).",
      "journal-title": "Nano. Lett."
    },
    {
      "key": "e_1_3_1_18_2",
      "doi-asserted-by": "crossref",
      "first-page": "1736",
      "DOI": "10.1002/adma.200400643",
      "volume": "16",
      "year": "2004",
      "unstructured": "D. E. Angelescu et al., Adv. Mater.16, 1736 (2004).",
      "journal-title": "Adv. Mater."
    },
    {
      "key": "e_1_3_1_19_2",
      "unstructured": "D. J. C. Herr in Future Fab International B. Dustrud Ed. (Montgomery Research Incorporated San Francisco CA 2005) issue 18 chap. 5."
    },
    {
      "key": "e_1_3_1_20_2",
      "doi-asserted-by": "crossref",
      "first-page": "1297",
      "DOI": "10.1063/1.115958",
      "volume": "68",
      "year": "1996",
      "unstructured": "J. Fujita, Y. Ohnishi, Y. Ochiai, S. Matsui, Appl. Phys. Lett.68, 1297 (1996).",
      "journal-title": "Appl. Phys. Lett."
    },
    {
      "key": "e_1_3_1_21_2",
      "doi-asserted-by": "crossref",
      "first-page": "703",
      "DOI": "10.1002/1521-4095(200105)13:10<703::AID-ADMA703>3.0.CO;2-A",
      "volume": "13",
      "year": "2001",
      "unstructured": "K. E. Gonsalves, L. Merhari, H. Wu, Y. Hu, Adv. Mater.13, 703 (2001).",
      "journal-title": "Adv. Mater."
    },
    {
      "key": "e_1_3_1_22_2",
      "doi-asserted-by": "crossref",
      "first-page": "9996",
      "DOI": "10.1063/1.481635",
      "volume": "112",
      "year": "2000",
      "unstructured": "Q. Wang, S. K. Nath, P. F. Nealey, J. J. dePablo, J. Chem. Phys.112, 9996 (2000).",
      "journal-title": "J. Chem. Phys."
    },
    {
      "key": "e_1_3_1_23_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/adma.200400763"
    },
    {
      "key": "e_1_3_1_24_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.275.5305.1458"
    },
    {
      "key": "e_1_3_1_25_2",
      "unstructured": "Additional materials and methods information is available on Science Online."
    },
    {
      "key": "e_1_3_1_26_2",
      "first-page": "56",
      "volume": "67",
      "year": "2003",
      "unstructured": "H. H. Solak et al., Microelectron. Eng.67\u201368, 56 (2003).",
      "journal-title": "Microelectron. Eng."
    },
    {
      "key": "e_1_3_1_27_2",
      "unstructured": "The lamellar spacing of the ternary block copolymer\u2013homopolymer blends can be controlled over a wide range of values by changing the volume fraction of homopolymer. Little is known about their behavior in the form of thin films but previous studies of phase diagrams and morphology in the bulk ( 34 35 ) provide useful insights."
    },
    {
      "key": "e_1_3_1_28_2",
      "doi-asserted-by": "crossref",
      "first-page": "934",
      "DOI": "10.1002/polb.20385",
      "volume": "43",
      "year": "2005",
      "unstructured": "M. M\u00fcller, G. D. Smith, J. Polym. Sci. B43, 934 (2005).",
      "journal-title": "J. Polym. Sci. B"
    },
    {
      "key": "e_1_3_1_29_2",
      "doi-asserted-by": "crossref",
      "first-page": "16",
      "DOI": "10.1021/ma011515t",
      "volume": "35",
      "year": "2002",
      "unstructured": "G. H. Fredrickson, V. Ganesan, F. Drolet, Macromolecules35, 16 (2002).",
      "journal-title": "Macromolecules"
    },
    {
      "key": "e_1_3_1_30_2",
      "doi-asserted-by": "crossref",
      "first-page": "1091",
      "DOI": "10.1021/ma951138i",
      "volume": "29",
      "year": "1996",
      "unstructured": "M. W. Matsen, F. S. Bates, Macromolecules29, 1091 (1996).",
      "journal-title": "Macromolecules"
    },
    {
      "key": "e_1_3_1_31_2",
      "doi-asserted-by": "crossref",
      "first-page": "886",
      "DOI": "10.1038/nmat1258",
      "volume": "3",
      "year": "2004",
      "unstructured": "A. Knoll et al., Nat. Mater.3, 886 (2004).",
      "journal-title": "Nat. Mater."
    },
    {
      "key": "e_1_3_1_32_2",
      "doi-asserted-by": "crossref",
      "first-page": "6137",
      "DOI": "10.1021/ma00099a031",
      "volume": "27",
      "year": "1994",
      "unstructured": "S. P. Gido, E. L. Thomas, Macromolecules27, 6137 (1994).",
      "journal-title": "Macromolecules"
    },
    {
      "key": "e_1_3_1_33_2",
      "doi-asserted-by": "crossref",
      "first-page": "8739",
      "DOI": "10.1021/ma000729s",
      "volume": "33",
      "year": "2000",
      "unstructured": "E. Burgaz, S. P. Gido, Macromolecules33, 8739 (2000).",
      "journal-title": "Macromolecules"
    },
    {
      "key": "e_1_3_1_34_2",
      "doi-asserted-by": "crossref",
      "first-page": "10315",
      "DOI": "10.1063/1.1519537",
      "volume": "117",
      "year": "2002",
      "unstructured": "D. Duque, K. Katsov, M. Schick, J. Chem. Phys.117, 10315 (2002).",
      "journal-title": "J. Chem. Phys."
    },
    {
      "key": "e_1_3_1_35_2",
      "doi-asserted-by": "crossref",
      "first-page": "849",
      "DOI": "10.1103/PhysRevLett.79.849",
      "volume": "79",
      "year": "1997",
      "unstructured": "F. S. Bates et al., Phys. Rev. Lett.79, 849 (1997).",
      "journal-title": "Phys. Rev. Lett."
    },
    {
      "key": "e_1_3_1_36_2",
      "doi-asserted-by": "crossref",
      "first-page": "2927",
      "DOI": "10.1063/1.458877",
      "volume": "93",
      "year": "1990",
      "unstructured": "D. Broseta, G. H. Fredrickson, J. Chem. Phys.93, 2927 (1990).",
      "journal-title": "J. Chem. Phys."
    },
    {
      "key": "e_1_3_1_37_2",
      "unstructured": "This research was supported by the Semiconductor Research Corporation (SRC) (2002-MJ-985) NSF through the Nanoscale Science and Engineering Center (DMR-0425880) and the Camille Dreyfus Teacher-Scholar Award. This work made use of the facilities and staff at the UW Center for Nanotechnology the Synchrotron Radiation Center at UW Madison (NSF DMR-0084402) and the Swiss Light Source at the Paul Scherrer Institute. The authors thank the John von Neumann-Institute for Computing J\u00fclich Germany for central processing unit time on the IBM p690-cluster. M.P.S. acknowledges a research fellowship from the SRC Graduate Fellowship Program."
    }
  ],
  "container-title": "Science",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://www.science.org/doi/pdf/10.1126/science.1111041",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2024,
        1,
        10
      ]
    ],
    "date-time": "2024-01-10T04:14:55Z",
    "timestamp": 1704860095000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://www.science.org/doi/10.1126/science.1111041"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2005,
        6,
        3
      ]
    ]
  },
  "references-count": 36,
  "journal-issue": {
    "issue": "5727",
    "published-print": {
      "date-parts": [
        [
          2005,
          6,
          3
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1126/science.1111041"
  ],
  "URL": "http://dx.doi.org/10.1126/science.1111041",
  "relation": {},
  "ISSN": [
    "0036-8075",
    "1095-9203"
  ],
  "subject": [],
  "container-title-short": "Science",
  "published": {
    "date-parts": [
      [
        2005,
        6,
        3
      ]
    ]
  }
}