Abstract
Invasive bacteria actively induce their own uptake by phagocytosis in normally nonphagocytic cells and then either establish a protected niche within which they survive and replicate, or disseminate from cell to cell by means of an actin-based motility process. The mechanisms underlying bacterial entry, phagosome maturation, and dissemination reveal common strategies as well as unique tactics evolved by individual species to establish infection.
References
70
Referenced
807
10.1083/jcb.200205011
10.1146/annurev.cellbio.18.012502.105845
10.1016/S1369-5274(03)00004-3
10.1007/s00232-002-2008-2
10.1126/science.276.5313.718
10.1242/jcs.114.1.21
10.1073/pnas.95.23.13658
-
M. A. Alrutzet al., Mol. Microbiol.42, 689 (2001).
(
10.1046/j.1365-2958.2001.02676.x
) / Mol. Microbiol. (2001) 10.1016/S0014-5793(01)03139-8
10.1016/S0014-5793(02)03745-6
10.1084/jem.20021363
10.1016/S0962-8924(02)00006-5
10.1016/S0092-8674(02)01136-4
10.1093/emboj/18.14.3956
10.1073/pnas.97.18.10008
- S. Sousa M. Lecuit P. Cossart in preparation.
- S. Sousaet al. J. Cell Sci. in press.
10.1242/jcs.115.17.3357
- H. Bierne et al . in preparation.
10.1016/S0092-8674(00)00141-0
10.1126/science.274.5288.780
10.1093/emboj/19.7.1458
10.1083/jcb.200104037
- O. Dussurget J. Pizarro-Cerda P. Cossart Annu. Rev. Microbiol. in press.
10.1128/CMR.14.3.584-640.2001
10.1126/science.290.5493.992
10.1006/smim.2000.0300
10.1128/IAI.71.6.3614-3618.2003
- S. Seveau S. Giroux H. Bierne P. Cossart in preparation.
10.1146/annurev.cellbio.17.1.53
- P. J. Sansonetti, FEMS Microbiol. Rev.25, 3 (2001). / FEMS Microbiol. Rev. (2001)
10.1016/S1369-5274(02)00002-4
10.1073/pnas.0535335100
10.1093/emboj/cdf457
10.1093/emboj/cdf319
10.1093/emboj/18.12.3249
10.1093/emboj/18.18.4926
10.1016/S0092-8674(00)81442-7
10.1073/pnas.95.24.14057
10.1073/pnas.96.18.10176
- J. Mounier P. J. Sansonetti G. Tran Van Nhieu in preparation.
- L. Bougnères et al . in preparation.
10.1093/emboj/cdf522
10.1093/emboj/cdg512
10.1016/S1097-2765(00)00141-6
10.1016/S0092-8674(03)00849-3
10.1093/emboj/18.21.5853
10.1034/j.1600-0854.2002.030301.x
10.1093/emboj/18.16.4394
10.1046/j.1462-5822.1999.00003.x
10.1093/emboj/cdg517
10.1073/pnas.90.22.10544
10.1016/S0962-8924(00)01871-7
10.1126/science.281.5373.105
10.1093/emboj/17.10.2767
10.1083/jcb.146.6.1319
10.1038/nature02318
- M. F. Kagnoff in Microbial Pathogenesis and the Intestinal Epithelial Cell G. A. Hecht Ed. (American Society for Microbiology Washington DC 2003).
10.1093/embo-reports/kve155
10.1126/science.1084677
10.1038/ni945
10.1074/jbc.273.49.32895
10.1073/pnas.96.5.2396
10.1126/science.285.5435.1920
10.1093/emboj/18.2.339
10.1038/ncb1021
10.1016/S1471-4914(02)02413-9
10.1126/science.1059852
10.1242/jcs.112.11.1697
- We thank E. Veiga E. Gouin and O. Dussurget for help with manuscript preparation and H. Bierne L. Bougnères and G. Tran van Nhieu for generously providing unpublished figures. The authors are international Scholars of the Howard Hughes Medical Institute.
Dates
Type | When |
---|---|
Created | 21 years, 4 months ago (April 8, 2004, 4:23 p.m.) |
Deposited | 1 year, 7 months ago (Jan. 9, 2024, 11:44 p.m.) |
Indexed | 19 hours, 18 minutes ago (Aug. 29, 2025, 5:53 a.m.) |
Issued | 21 years, 4 months ago (April 9, 2004) |
Published | 21 years, 4 months ago (April 9, 2004) |
Published Print | 21 years, 4 months ago (April 9, 2004) |
@article{Cossart_2004, title={Bacterial Invasion: The Paradigms of Enteroinvasive Pathogens}, volume={304}, ISSN={1095-9203}, url={http://dx.doi.org/10.1126/science.1090124}, DOI={10.1126/science.1090124}, number={5668}, journal={Science}, publisher={American Association for the Advancement of Science (AAAS)}, author={Cossart, Pascale and Sansonetti, Philippe J.}, year={2004}, month=apr, pages={242–248} }