DOI: 10.1124/mol.59.5.949. Cyanovirin-N Defines a New Class of Antiviral Agent Targeting N-Linked, High-Mannose Glycans in an Oligosaccharide-Specific Manner

Cyanovirin-N Defines a New Class of Antiviral Agent Targeting N-Linked, High-Mannose Glycans in an Oligosaccharide-Specific Manner

10.1124/mol.59.5.949

Crossref journal-article

Elsevier BV

Molecular Pharmacology (78)

Bibliography

Bolmstedt, A. J., OâKeefe, B. R., Shenoy, S. R., McMahon, J. B., & Boyd, M. R. (2001). Cyanovirin-N Defines a New Class of Antiviral Agent Targeting N-Linked, High-Mannose Glycans in an Oligosaccharide-Specific Manner. Molecular Pharmacology, 59(5), 949â954.

Authors 5

Anders J. Bolmstedt (first)
Barry R. O'Keefe (additional)
Shilpa R. Shenoy (additional)
James B. McMahon (additional)
Michael R. Boyd (additional)

References 25 Referenced 130

10.1128/JVI.59.3.703-713.1986 / J Virol / Primate cytomegalovirus glycoproteins: lectin binding properties and sensitivities to glycosidases. by Benko (1986)
10.1038/828
10.1099/0022-1317-72-6-1269 / J Gen Virol / Effects of mutations in glycosylation sites and disulphide bonds on processing, CD4-binding and fusion activity of human immunodeficiency virus envelope glycoproteins. by Bolmstedt (1991)
10.1128/AAC.41.7.1521 / Antimicrob Agents Chemother / Discovery of cyanovirin-N, a novel human immunodeficiency virus- inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. by Boyd (1997)
10.1016/0163-7258(87)90066-0
10.1128/JVI.74.10.4562-4569.2000
10.1128/JVI.73.5.4360-4371.1999 / J Virol / Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4- induced conformational changes in gp120. by Esser (1999)
10.1242/jcs.1988.Supplement_9.6 / J Cell Sci Suppl / The structure and function of vertebrate mannose lectin-like proteins. by Ezekowitz (1988)
10.1002/eji.1830230128 / Eur J Immunol / Inhibition of human immunodeficiency virus infection by the lectin jacalin and by a derived peptide showing a sequence similarity with gp120. by Favero (1993)
10.1016/S0021-9258(18)37849-9 / J Biol Chem / Carbohydrates of human immunodeficiency virus. Structures of oligosaccharides linked to the envelope glycoprotein 120. by Geyer (1988)
10.1089/aid.1993.9.431
10.1007/BF01310789
10.3181/00379727-118-29763
10.1006/bbrc.1997.7203
10.1016/S0021-9258(18)60646-5 / J Biol Chem / Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo- 2′,3′-dideoxyadenosine derivatives. by Haertle (1988)
10.1007/BF01718221
10.1016/S0021-9258(18)86956-3 / J Biol Chem / Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. by Leonard (1990)
10.1006/prep.1997.0838
10.1124/mol.58.5.982
10.1093/glycob/9.1.73
10.1021/bi00338a028
10.1016/0076-6879(87)38064-4 / Methods Enzymol / Endo-beta-N-acetylglucos-aminidase H from Streptomyces plicatus. by Trimble (1987)
10.1073/pnas.88.23.10744
10.1128/JVI.44.1.241-248.1982 / J Virol / Endo-beta-N-acetylglucosaminidase H sensitivity of precursors to herpes simplex virus type 1 glycoproteins gB and gC. by Wenske (1982)
10.1016/S0021-9258(17)42963-2 / J Biol Chem / Control of asparagine-linked oligosaccharide chain processing: studies on bovine pancreatic ribonuclease B. An in vitro system for the processing of exogenous glycoproteins. by Williams (1984)

Dates

Type	When
Created	7 years, 7 months ago (Jan. 8, 2018, 3:42 p.m.)
Deposited	8 months, 4 weeks ago (Nov. 27, 2024, 1:36 p.m.)
Indexed	1 day, 5 hours ago (Aug. 26, 2025, 2:29 a.m.)
Issued	24 years, 3 months ago (May 1, 2001)
Published	24 years, 3 months ago (May 1, 2001)
Published Online	24 years, 3 months ago (May 1, 2001)
Published Print	24 years, 3 months ago (May 1, 2001)

Funders 0

None

BibTeX

@article{Bolmstedt_2001, title={Cyanovirin-N Defines a New Class of Antiviral Agent Targeting N-Linked, High-Mannose Glycans in an Oligosaccharide-Specific Manner}, volume={59}, ISSN={1521-0111}, url={http://dx.doi.org/10.1124/mol.59.5.949}, DOI={10.1124/mol.59.5.949}, number={5}, journal={Molecular Pharmacology}, publisher={Elsevier BV}, author={Bolmstedt, Anders J. and O’Keefe, Barry R. and Shenoy, Shilpa R. and McMahon, James B. and Boyd, Michael R.}, year={2001}, month=may, pages={949–954} }

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