DOI: 10.1124/mol.105.019695. A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling

A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling

10.1124/mol.105.019695

Crossref journal-article

Elsevier BV

Molecular Pharmacology (78)

Bibliography

Ii, M., Matsunaga, N., Hazeki, K., Nakamura, K., Takashima, K., Seya, T., Hazeki, O., Kitazaki, T., & Iizawa, Y. (2006). A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling. Molecular Pharmacology, 69(4), 1288â1295.

Authors 9

Masayuki Ii (first)
Naoko Matsunaga (additional)
Kaoru Hazeki (additional)
Kazuyo Nakamura (additional)
Katsunori Takashima (additional)
Tsukasa Seya (additional)
Osamu Hazeki (additional)
Tomoyuki Kitazaki (additional)
Yuji Iizawa (additional)

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Dates

Type	When
Created	19 years, 8 months ago (Dec. 22, 2005, 9:13 p.m.)
Deposited	6 months ago (Feb. 20, 2025, 4:06 a.m.)
Indexed	2 days, 16 hours ago (Aug. 23, 2025, 1:01 a.m.)
Issued	19 years, 4 months ago (April 1, 2006)
Published	19 years, 4 months ago (April 1, 2006)
Published Print	19 years, 4 months ago (April 1, 2006)

Funders 0

None

BibTeX

@article{Ii_2006, title={A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling}, volume={69}, ISSN={0026-895X}, url={http://dx.doi.org/10.1124/mol.105.019695}, DOI={10.1124/mol.105.019695}, number={4}, journal={Molecular Pharmacology}, publisher={Elsevier BV}, author={Ii, Masayuki and Matsunaga, Naoko and Hazeki, Kaoru and Nakamura, Kazuyo and Takashima, Katsunori and Seya, Tsukasa and Hazeki, Osamu and Kitazaki, Tomoyuki and Iizawa, Yuji}, year={2006}, month=apr, pages={1288–1295} }

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