DOI: 10.1111/j.1748-1716.1961.tb02121.x. Effects of Motor Inactivation on the Chemical Sensitivity of Skeletal Muscle

Effects of Motor Inactivation on the Chemical Sensitivity of Skeletal Muscle

10.1111/j.1748-1716.1961.tb02121.x

Crossref journal-article

Wiley

Acta Physiologica Scandinavica (311)

Abstract

AbstractJohns T. R. and S. Thesleff. Effects of motor inactivation on the chemical sensitivity of skeletal muscle.In order to determine whether the lack of motor nerve impulses, without denervation per se, alters the chemically sensitive area in skeletal muscle, the size of the ACh‐sensitive areas in muscle fibres of cat tenuissimus were measured after isolation of the motor neurones by severance of the dorsal roots below a lower lumbar cord transection. The sensitivity of the individual muscle fibre to ACh was determined by iontophoretic micro‐application of the drug, and by intracellular recording of the potential change. The frequency of miniature end‐plate potentials, their amplitude, and their time course, were relatively unaffected by the isolation procedure. The procedure also caused little increase in the size of the ACh‐sensitive surface. Therefore, inactivation per se did not alter the chemically sensitive area.

Bibliography

Johns, T. R., & Thesleff, S. (1961). Effects of Motor Inactivation on the Chemical Sensitivity of Skeletal Muscle. Acta Physiologica Scandinavica, 51(2â3), 136â141. Portico.

Authors 2

T. R. Johns (first)
S. Thesleff (additional)

References 10 Referenced 32

10.1113/jphysiol.1959.sp006233
10.1152/ajplegacy.1939.126.3.731 / Amer. J. Physiol. / The sensitizations of motorneurones by partial “denervation by Cannon W. B. (1939)
10.1113/jphysiol.1944.sp004074
10.1111/j.1600-0773.1960.tb01232.x
10.1113/jphysiol.1960.sp006416
10.1152/jn.1942.5.5.373 / J. Neurophysiol. / A comparison of effects of upper and lower motor neurone lesions on skeletal muscle by Solandt D. Y. (1942)
10.1113/jphysiol.1960.sp006463
{'key': 'e_1_2_1_8_1', 'article-title': 'Effects of motor innervation on the chemical sensitivity of skeletal muscle', 'author': 'Thesleff S.', 'journal-title': 'Physiol. Rev.'} / Physiol. Rev. / Effects of motor innervation on the chemical sensitivity of skeletal muscle by Thesleff S.
10.1002/cne.900670107
10.1002/cne.900670206

Dates

Type	When
Created	16 years, 8 months ago (Dec. 9, 2008, 12:05 a.m.)
Deposited	2 years ago (Aug. 30, 2023, 7:18 a.m.)
Indexed	1 year, 10 months ago (Nov. 1, 2023, 3:39 a.m.)
Issued	64 years, 7 months ago (Feb. 1, 1961)
Published	64 years, 7 months ago (Feb. 1, 1961)
Published Online	16 years, 8 months ago (Dec. 8, 2008)
Published Print	64 years, 7 months ago (Feb. 1, 1961)

Funders 0

None

BibTeX

@article{Johns_1961, title={Effects of Motor Inactivation on the Chemical Sensitivity of Skeletal Muscle}, volume={51}, ISSN={1365-201X}, url={http://dx.doi.org/10.1111/j.1748-1716.1961.tb02121.x}, DOI={10.1111/j.1748-1716.1961.tb02121.x}, number={2–3}, journal={Acta Physiologica Scandinavica}, publisher={Wiley}, author={Johns, T. R. and Thesleff, S.}, year={1961}, month=feb, pages={136–141} }

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