DOI: 10.1111/j.1742-4658.2004.04473.x. Data‐driven docking for the study of biomolecular complexes

Data‐driven docking for the study of biomolecular complexes
10.1111/j.1742-4658.2004.04473.x
Crossref journal-article
Wiley
The FEBS Journal (311)
Abstract
With the amount of genetic information available, a lot of attention has focused on systems biology, in particular biomolecular interactions. Considering the huge number of such interactions, and their often weak and transient nature, conventional experimental methods such as X‐ray crystallography and NMR spectroscopy are not sufficient to gain structural insight into these. A wealth of biochemical and/or biophysical data can, however, readily be obtained for biomolecular complexes. Combining these data with docking (the process of modeling the 3D structure of a complex from its known constituents) should provide valuable structural information and complement the classical structural methods. In this review we discuss and illustrate the various sources of data that can be used to map interactions and their combination with docking methods to generate structural models of the complexes. Finally a perspective on the future of this kind of approach is given.
Bibliography
van Dijk, A. D. J., Boelens, R., & Bonvin, A. M. J. J. (2004). Dataâdriven docking for the study of biomolecular complexes. The FEBS Journal, 272(2), 293â312. Portico.
Authors 3
Aalt D. J. van Dijk (first)
Rolf Boelens (additional)
Alexandre M. J. J. Bonvin (additional)
References 190 Referenced 116
Dates
Type	When
Created	20 years, 7 months ago (Jan. 12, 2005, 9:01 a.m.)
Deposited	1 year, 9 months ago (Oct. 31, 2023, 6:53 p.m.)
Indexed	3 weeks, 5 days ago (July 30, 2025, 11:22 a.m.)
Issued	20 years, 8 months ago (Dec. 21, 2004)
Published	20 years, 8 months ago (Dec. 21, 2004)
Published Online	20 years, 8 months ago (Dec. 21, 2004)
Published Print	20 years, 7 months ago (Jan. 1, 2005)
Funders 0
None
BibTeX
@article{van_Dijk_2004, title={Data‐driven docking for the study of biomolecular complexes}, volume={272}, ISSN={1742-4658}, url={http://dx.doi.org/10.1111/j.1742-4658.2004.04473.x}, DOI={10.1111/j.1742-4658.2004.04473.x}, number={2}, journal={The FEBS Journal}, publisher={Wiley}, author={van Dijk, Aalt D. J. and Boelens, Rolf and Bonvin, Alexandre M. J. J.}, year={2004}, month=dec, pages={293–312} }
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