DOI: 10.1111/j.1699-0463.1992.tb00893.x. Phagocyte killing of <i>Campylobacter jejuni</i> in relation to oxidative activation

Phagocyte killing of Campylobacter jejuni in relation to oxidative activation

10.1111/j.1699-0463.1992.tb00893.x

Crossref journal-article

Wiley

APMIS (311)

Abstract

When studying the interaction between Campylobacter jejuni and human neutrophils, we found that four different clinical isolates showed a great variability in this association. Also the ability to induce neutrophil production of oxidative metabolites, measured as chemiluminescence (CL), differed between the strains. Surprisingly, strain 1, which showed weak interaction with neutrophils and high resistance to killing, induced the highest CL response. All strains evoked an intracellular CL response, and three strains also gave rise to an extracellular response. This extracellular release of toxic oxygen species might contribute to the local tissue damage during infection. There was no clear correlation between association, killing and oxidative response. However, one strain that only evoked an intracellular generation of oxygen metabolites also showed the highest sensitivity to killing. Phagocytosis was increased up to ten times after opsonization with normal human serum. The intracellular CL production increased several fold, whereas the extracellular generation of oxygen species disappeared or was considerably decreased after opsonization. These results indicate that complement‐opsonized C. jejuni are phagocytosed and readily attacked by the oxidative defence system within the phagosome.

Bibliography

WALAN, A., DAHLGREN, C., KIHLSTRÃM, E., STENDAHL, O., & LOCK, R. (1992). Phagocyte killing of Campylobacter jejuni in relation to oxidative activation. APMIS, 100(1â6), 424â430. Portico.

Authors 5

ASA WALAN (first)
CLAES DAHLGREN (additional)
ERIK KIHLSTRÖM (additional)
OLLE STENDAHL (additional)
RONNY LOCK (additional)

References 33 Referenced 17

10.1128/iai.58.6.1848-1852.1990 / Infect. Immun. / A domestic ferret model of immunity to Campylobacter jejuni‐induced enteric disease by Bell J. A. (1990)
10.1136/gut.30.7.906
10.1093/infdis/157.3.472
10.1016/0016-5085(80)90855-0
10.1093/infdis/151.2.227
10.1128/iai.56.1.99-105.1988 / Infect. Immun. / Mucosal and systemic immunity to Campylobacter jejuni in rabbits after gastric inoculation by Burr D. H. (1988)
{'issue': '97', 'key': 'e_1_2_1_8_2', 'first-page': '77', 'article-title': 'Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation and of granulocytes by combining centrifugation and sedimentation at 1 × g. Scand', 'author': 'Boyum A.', 'year': '1968', 'journal-title': 'J. Clin. Lab. Invest.'} / J. Clin. Lab. Invest. / Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation and of granulocytes by combining centrifugation and sedimentation at 1 × g. Scand by Boyum A. (1968)
10.1128/iai.57.7.2214-2222.1989 / Infect. Immun. / Cellular events and intracellular survival of Campylobacter jejuni during infection of HEp‐2 cells by Melo M. A. (1989)
10.1128/iai.58.6.1749-1756.1990 / Infect. Immun. / Identification of Campylobacter jejuni surface proteins that bind to eucaryotic cells in vitro by Melo M. A. (1990)
10.1093/ajcp/73.5.706
10.1128/IAI.54.2.283-287.1986
10.1093/infdis/148.2.292
10.1128/iai.55.10.2526-2530.1987 / Infect. Immun. / Production of a unique cytotoxin by Campylobacter jejuni by Guerrant R. L. (1987)
10.1111/j.1574-6968.1977.tb00651.x
10.1016/S0889-8588(18)30624-5
10.1128/JCM.24.2.275-281.1986
10.1128/IAI.48.2.446-451.1985
10.1128/iai.57.10.2984-2990.1989 / Infect. Immun. / Adhesion to and invasion of HEp‐2 cells by Campylobacter spp by Konkel M. E. (1989)
10.1093/infdis/162.4.888
10.1128/iai.51.2.536-546.1986 / Infect. Immun. / Mucus colonisation as a determinant of pathogenicity in intestinal infection by Campylobacter jejuni: a mouse cecal model by Lee A. (1986)
10.1128/IAI.58.1.37-42.1990
10.1016/0003-2697(88)90213-8
10.1128/jcm.28.6.1314-1320.1990 / J. Clin. Microbiol. / Isolation, characterization, and host‐cell‐binding properties of a cytotoxin from Campylobacter jejuni by Mahajan S. (1990)
10.1128/IAI.57.8.2542-2546.1989
10.1128/IAI.53.1.141-148.1986
10.1111/j.1365-2672.1987.tb02379.x
10.1128/iai.59.11.4168-4172.1991 / Infect. Immun. / Extracellular release of reactive oxygen species from human neutrophils upon interaction with Escherichia coli strains causing renal scarring by Mundi H. (1991)
10.1128/iai.47.2.353-359.1985 / Infect. Immun. / Lipopolysaccharide characteristics of pathogenic Campylobacters by Perez‐Perez G. I. (1985)
10.1016/S0022-3476(05)82652-6
10.1128/IAI.57.5.1438-1444.1989
10.1093/infdis/148.1.82
10.1016/S0176-6724(87)80031-7
10.1111/j.1699-0463.1988.tb00986.x

Dates

Type	When
Created	16 years ago (Aug. 15, 2009, 6:16 a.m.)
Deposited	2 years ago (Aug. 31, 2023, 1:35 a.m.)
Indexed	1 year, 9 months ago (Nov. 20, 2023, 1:23 p.m.)
Issued	33 years, 8 months ago (Jan. 1, 1992)
Published	33 years, 8 months ago (Jan. 1, 1992)
Published Online	16 years ago (Aug. 15, 2009)
Published Print	33 years, 8 months ago (Jan. 1, 1992)

Funders 0

None

BibTeX

@article{WALAN_1992, title={Phagocyte killing of Campylobacter jejuni in relation to oxidative activation}, volume={100}, ISSN={1600-0463}, url={http://dx.doi.org/10.1111/j.1699-0463.1992.tb00893.x}, DOI={10.1111/j.1699-0463.1992.tb00893.x}, number={1–6}, journal={APMIS}, publisher={Wiley}, author={WALAN, ASA and DAHLGREN, CLAES and KIHLSTRÖM, ERIK and STENDAHL, OLLE and LOCK, RONNY}, year={1992}, month=jan, pages={424–430} }

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