DOI: 10.1111/j.1651-2227.1991.tb11916.x. Neonatal Sepsis in Pakistan: Presentation and Pathogens

Neonatal Sepsis in Pakistan: Presentation and Pathogens

10.1111/j.1651-2227.1991.tb11916.x

Crossref journal-article

Wiley

Acta Paediatrica (311)

Abstract

ABSTRACT. The case records of all neonates admitted to the neonatal unit at Aga Khan University Hospital (Karachi) in a 30 month period (Nov. 86April 89) were analysed. Of 60 neonates with confirmed sepsis, 33 (55%) had non‐nosocomial infection (NNC) whereas 27 (45 %) had nosocomial sepsis (NC). The most common organisms causing early‐onset NNC sepsis were Klebsiella species (53%) and Escherichia coli (10%), whereas the organisms causing late‐onset NNC sepsis included Salmonella parathypi (21%), Group A Streptococcus (21%), Escherichia coli (14%) and Pseudomonas species (14%). Klebsiella was the most common organism causing NC sepsis, others being Staphylococcus aureus(15%) and Serratia species (15%). The mortality in NC sepsis, early‐onset and late onset NNC sepsis was 44%, 26% and 43%, respectively. Risk factors associated with NNC sepsis included low birthweight, prematurity and prolonged and complicated deliveries. There was a high incidence of drug resistance to ampicillin and gentamicin among gram‐negative organisms causing sepsis (mean 67 %).

Bibliography

BHUTTA, Z. A., NAQVI, S. H., MUZAFFAR, T., & FAROOQUI, B. J. (1991). Neonatal Sepsis in Pakistan: Presentation and Pathogens. Acta Paediatrica, 80(6â7), 596â601. Portico.

Authors 4

ZULFIQAR A. BHUTTA (first)
SHEHLA H. NAQVI (additional)
TAHSEEN MUZAFFAR (additional)
BADR J. FAROOQUI (additional)

References 25 Referenced 32

10.1056/NEJM198103123041105
10.1001/archpedi.1981.02130260032010
10.1097/00006454-198501000-00010
10.1542/pir.1-1-5
10.1093/infdis/144.5.449
10.1056/NEJM197606102942403
{'key': 'e_1_2_1_7_2', 'first-page': '225', 'article-title': 'Neonatal septicemia in Kuwait', 'volume': '14', 'author': 'Kuruvilla AC.', 'year': '1980', 'journal-title': 'J Kwt Med Assoc'} / J Kwt Med Assoc / Neonatal septicemia in Kuwait by Kuruvilla AC. (1980)
10.1093/tropej/33.3.131
{'key': 'e_1_2_1_9_2', 'first-page': '1011', 'article-title': 'Bacteriological profile of neonatal septicemia', 'volume': '11', 'author': 'Sharma PP', 'year': '1987', 'journal-title': 'Indian Pediatr'} / Indian Pediatr / Bacteriological profile of neonatal septicemia by Sharma PP (1987)
10.1001/archpedi.1988.02150010029014
10.1093/ajcp/45.4_ts.493 / Am J Clin Pathol / Antibiotic susceptibility testing by a standardized single disc method by Bauer AW (1966)
10.1111/j.1651-2227.1989.tb10885.x
10.1093/infdis/148.5.795
{'key': 'e_1_2_1_14_2', 'first-page': '327', 'article-title': 'Neonatal sepsis‐‐‐etiological study', 'volume': '37', 'author': 'Khan IA', 'year': '1987', 'journal-title': 'J Pak Med Assoc'} / J Pak Med Assoc / Neonatal sepsis‐‐‐etiological study by Khan IA (1987)
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10.1136/adc.60.6.542
10.1136/adc.58.9.728
10.1097/00006454-198609000-00009
10.1093/infdis/138.3.293
{'key': 'e_1_2_1_23_2', 'first-page': '387', 'article-title': 'Emergence of B‐lactam multiresistant variants of gram negative bacilli in the presence of cefotaxime', 'volume': '17', 'author': 'Svarva PL', 'year': '1985', 'journal-title': 'Scand J Infect Dis'} / Scand J Infect Dis / Emergence of B‐lactam multiresistant variants of gram negative bacilli in the presence of cefotaxime by Svarva PL (1985)
10.1111/j.1651-2227.1987.tb10543.x
10.3109/00365548409068406

Dates

Type	When
Created	17 years, 7 months ago (Jan. 21, 2008, 1:12 p.m.)
Deposited	2 years ago (Aug. 30, 2023, 12:25 a.m.)
Indexed	1 year, 10 months ago (Oct. 26, 2023, 9:17 p.m.)
Issued	34 years, 3 months ago (June 1, 1991)
Published	34 years, 3 months ago (June 1, 1991)
Published Online	17 years, 7 months ago (Jan. 21, 2008)
Published Print	34 years, 3 months ago (June 1, 1991)

Funders 0

None

BibTeX

@article{BHUTTA_1991, title={Neonatal Sepsis in Pakistan: Presentation and Pathogens}, volume={80}, ISSN={1651-2227}, url={http://dx.doi.org/10.1111/j.1651-2227.1991.tb11916.x}, DOI={10.1111/j.1651-2227.1991.tb11916.x}, number={6–7}, journal={Acta Paediatrica}, publisher={Wiley}, author={BHUTTA, ZULFIQAR A. and NAQVI, SHEHLA H. and MUZAFFAR, TAHSEEN and FAROOQUI, BADR J.}, year={1991}, month=jun, pages={596–601} }

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