DOI: 10.1111/j.1600-051x.1993.tb00694.x. Natural distribution of 5 bacteria associated with periodontal disease

Natural distribution of 5 bacteria associated with periodontal disease

10.1111/j.1600-051x.1993.tb00694.x

Crossref journal-article

Wiley

Journal of Clinical Periodontology (311)

Abstract

Abstract The purpose of this study was to determine the prevalence and distribution of 5 bacterial pathogens in subgingival plaque, their relationship with each other and probing depth. Plaque was collected from 6905 sites in 938 subjects. A bacterial concentration fluorescence immunoassay and bacterial specific monoclonal antibodies were used to determine the presence and level of P. gingivalis (Pg), A. actinomycetemcomitans (Aa), P. intermedia (Pi), E. carrodens (Ec) and F. nucleatum (Fn) in each plaque sample. The prevalence in subjects was lowest for Pg (32%) and highest for Ec (49%). The site‐based frequency distribution of these bacterial species ranged from 10.3% for Pg to 18.7% for Ec. Pi and Ec were the bacterial combination most often found together in a subject (27.2%). While 64.0% of the sites were without any of the 5 bacterial species evaluated, 20.2% had only 1 of the 5 bacterial species evaluated. The remaining 15.8% of sites had at least 2 bacteria species present. There was a general linear association of the detection level of bacterial species and probing depth. The odds ratios were 3.9 (Pg). 3.0 (Aa), 4.0 (Pi). 2.7 (Ec) and 2.8 (Fn) of finding high levels of these bacterial pathogens at > 5 mm probing depth (p≤ 0.01). Mean probing depth at molar sites without a specific bacteria was greater (p≤ 0.01) in subjects wish a specific bacterium compared to molar sites in subjects without the bacteria. The observation that these 5 bacterial species frequently inhabit the subgingival environment, yet are not associated with advanced disease, suggest that a susceptible host is required, in addition to a “pathogenic bacteria”, before disease progression may occur.

Bibliography

Wolff, L. F., Aeppli, D. M., Pihlstrom, B., Anderson, L., Stoltenberg, J., Osborn, J., Hardie, N., Shelburne, C., & Fischer, G. (1993). Natural distribution of 5 bacteria associated with periodontal disease. Journal of Clinical Periodontology, 20(10), 699â706. Portico.

Authors 9

L. F. Wolff (first)
D. M. Aeppli (additional)
B. Pihlstrom (additional)
L. Anderson (additional)
J. Stoltenberg (additional)
J. Osborn (additional)
N. Hardie (additional)
C. Shelburne (additional)
G. Fischer (additional)

References 28 Referenced 78

10.3109/00016359009029073
10.1902/jop.1992.63.2.93
10.1902/jop.1989.60.11.611
{'key': 'e_1_2_1_5_1', 'first-page': '1633', 'article-title': 'Specific subgingival bacteria and diagnosis of gingivitis and periodontitis', 'volume': '68', 'author': 'Christersson L. W.', 'year': '1989', 'journal-title': 'Journal of Dental Research'} / Journal of Dental Research / Specific subgingival bacteria and diagnosis of gingivitis and periodontitis by Christersson L. W. (1989)
10.1111/j.1600-051X.1992.tb01146.x
10.1111/j.1600-051X.1988.tb01590.x
{'key': 'e_1_2_1_8_1', 'volume-title': 'Statistical Methods for Rates & Proportions', 'author': 'Fleiss J. L.', 'year': '1981'} / Statistical Methods for Rates & Proportions by Fleiss J. L. (1981)
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10.1902/jop.1991.62.9.558
10.1111/j.1600-0765.1993.tb01043.x
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{'key': 'e_1_2_1_19_1', 'first-page': '96', 'volume-title': 'Statistical methods', 'author': 'Snedecor G. W.', 'year': '1980'} / Statistical methods by Snedecor G. W. (1980)
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Stollenberg J. L. Osborn J. B. Pihlstrom B. L. Hardie N. A. Aeppli D. M. Huso B. A. Bakdash M. B. Fischer G. E.(1993)Demographic medical behavioral and periodontal characteristics of a large sample Journal of Periodontology in press.
10.1111/j.1600-0765.1984.tb00819.x
10.1128/jcm.29.8.1645-1651.1991 / Journal of Clinical Microbiology / Fluorescence immunoassay for detecting periodontal bacterial pathogens in plaque by Wolff L. F. (1991)
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10.1111/j.1600-0765.1985.tb00431.x
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Dates

Type	When
Created	19 years, 8 months ago (Dec. 13, 2005, 4:44 a.m.)
Deposited	1 year, 10 months ago (Oct. 26, 2023, 1:35 a.m.)
Indexed	1 month, 4 weeks ago (July 7, 2025, 7:25 a.m.)
Issued	31 years, 10 months ago (Nov. 1, 1993)
Published	31 years, 10 months ago (Nov. 1, 1993)
Published Online	19 years, 8 months ago (Dec. 13, 2005)
Published Print	31 years, 10 months ago (Nov. 1, 1993)

Funders 0

None

BibTeX

@article{Wolff_1993, title={Natural distribution of 5 bacteria associated with periodontal disease}, volume={20}, ISSN={1600-051X}, url={http://dx.doi.org/10.1111/j.1600-051x.1993.tb00694.x}, DOI={10.1111/j.1600-051x.1993.tb00694.x}, number={10}, journal={Journal of Clinical Periodontology}, publisher={Wiley}, author={Wolff, L. F. and Aeppli, D. M. and Pihlstrom, B. and Anderson, L. and Stoltenberg, J. and Osborn, J. and Hardie, N. and Shelburne, C. and Fischer, G.}, year={1993}, month=nov, pages={699–706} }

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