DOI: 10.1111/j.1600-0447.1982.tb06719.x. Pneumoencephalographic evidence of brain atrophy in acute and chronic schizophrenic patients

Pneumoencephalographic evidence of brain atrophy in acute and chronic schizophrenic patients

10.1111/j.1600-0447.1982.tb06719.x

Crossref journal-article

Wiley

Acta Psychiatrica Scandinavica (311)

Abstract

Pneumoencephalography (PEG) was carried out in 50 patients of both sexes consecutively discharged from a psychiatric department with a diagnosis of acute schizophrenia. At clinical follow‐up with a mean observation time of 8 years the diagnosis was verified in 38 patients, while 12 were considered to have had a reactive psychosis. The PEG findings and clinical findings in these two groups are compared, and compared to corresponding findings in 101 chronic schizophrenics previously studied with the same method.Linear measurements were used in estimating the size of the ventricular system, which was safely within normal limits in all but three of the 50 patients. Mean ventricular size did not differ significantly in the two groups of acute psychoses. No case of cortical atrophy was found. More than half of the chronic schizophrenics had abnormal PEG's, the typical finding being a bilateral enlargement of the ventricular system. The mean size of all parts of the ventricular system was significantly higher than in the acute schizophrenics. A close correlation was found between mental deterioration and ventricular enlargement. The most reasonable explanation of these findings is that schizophrenia is an inborn error of metabolism, disturbing normal brain function and in the long run leading to degenerative changes of the nervous tissue.

Bibliography

Haug, J. O. (1982). Pneumoencephalographic evidence of brain atrophy in acute and chronic schizophrenic patients. Acta Psychiatrica Scandinavica, 66(5), 374â383. Portico.

Authors 1

J. O. Haug (first)

References 32 Referenced 43

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{'key': 'e_1_2_1_3_1', 'first-page': '209', 'volume-title': 'Clinical genetics in psychiatry: Problems in nosological classification', 'author': 'Asano N.', 'year': '1967'} / Clinical genetics in psychiatry: Problems in nosological classification by Asano N. (1967)
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{'key': 'e_1_2_1_9_1', 'first-page': '361', 'article-title': 'Zur Anwendung der Computertomographie (CT) in der klinischen Psychiatrie', 'volume': '46', 'author': 'Gall M. v.', 'year': '1978', 'journal-title': 'Fortschr. Neurol. Psychiat'} / Fortschr. Neurol. Psychiat / Zur Anwendung der Computertomographie (CT) in der klinischen Psychiatrie by Gall M. v. (1978)
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{'key': 'e_1_2_1_11_1', 'first-page': '1', 'article-title': 'Pneumoencephalographic studies in mental disease', 'volume': '165', 'author': 'Haug J. O.', 'year': '1962', 'journal-title': 'Acta psychiat. scand. Suppl'} / Acta psychiat. scand. Suppl / Pneumoencephalographic studies in mental disease by Haug J. O. (1962)
{'key': 'e_1_2_1_12_1', 'first-page': '47', 'article-title': 'Pneumoencephalography and prognosis in mental disease', 'volume': '217', 'author': 'Haug J. O.', 'year': '1970', 'journal-title': 'Acta psychiat. scand. Suppl'} / Acta psychiat. scand. Suppl / Pneumoencephalography and prognosis in mental disease by Haug J. O. (1970)
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{'key': 'e_1_2_1_20_1', 'article-title': 'The prognosis in schizophrenia', 'volume': '110', 'author': 'Langfeldt G.', 'year': '1956', 'journal-title': 'Acta psychiat. scand. Suppl'} / Acta psychiat. scand. Suppl / The prognosis in schizophrenia by Langfeldt G. (1956)
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Dates

Type	When
Created	18 years ago (Aug. 23, 2007, 6:10 a.m.)
Deposited	1 year, 9 months ago (Nov. 8, 2023, 12:34 p.m.)
Indexed	11 months, 3 weeks ago (Sept. 10, 2024, 5:52 p.m.)
Issued	42 years, 10 months ago (Nov. 1, 1982)
Published	42 years, 10 months ago (Nov. 1, 1982)
Published Online	18 years ago (Aug. 23, 2007)
Published Print	42 years, 10 months ago (Nov. 1, 1982)

Funders 0

None

BibTeX

@article{Haug_1982, title={Pneumoencephalographic evidence of brain atrophy in acute and chronic schizophrenic patients}, volume={66}, ISSN={1600-0447}, url={http://dx.doi.org/10.1111/j.1600-0447.1982.tb06719.x}, DOI={10.1111/j.1600-0447.1982.tb06719.x}, number={5}, journal={Acta Psychiatrica Scandinavica}, publisher={Wiley}, author={Haug, J. O.}, year={1982}, month=nov, pages={374–383} }

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