DOI: 10.1111/j.1540-8159.1998.tb00148.x. Taking the “Idio” out of “Idiosyncratic”: Predicting Torsades de Pointes

Taking the “Idio” out of “Idiosyncratic”: Predicting Torsades de Pointes

10.1111/j.1540-8159.1998.tb00148.x

Crossref journal-article

Wiley

Pacing and Clinical Electrophysiology (311)

Bibliography

RODEN, D. M. (1998). Taking the âIdioâ out of âIdiosyncraticâ: Predicting Torsades de Pointes. Pacing and Clinical Electrophysiology, 21(5), 1029â1034. Portico.

Authors 1

DAN M. RODEN (first)

References 48 Referenced 552

10.1161/01.CIR.30.1.17
10.1007/BF01778848
10.1161/01.CIR.44.1.130
10.1016/0002-8703(86)90010-4
10.1056/NEJM199407073310108
10.1016/0735-1097(96)00121-0
10.1161/01.CIR.94.7.1613
10.1016/S0140-6736(96)02149-6
10.1136/hrt.48.3.213
10.1016/S0735-1097(96)00377-4
10.1161/01.RES.72.3.631
10.1161/01.RES.79.3.474
10.1161/01.CIR.86.5.1376
10.1136/hrt.63.6.342
10.1016/0002-8703(84)90081-4
10.1001/jama.1993.03510210076031
10.1093/cvr/27.12.2186
10.1111/j.1540-8159.1998.tb00150.x
10.1136/hrt.32.1.57
10.1002/clc.4960170410
10.1136/pgmj.68.798.289
10.1016/0735-1097(95)00286-5
{'key': 'e_1_2_1_24_2', 'first-page': '1202', 'article-title': 'Increased sensitivity to QT prolonging drug therapy immediately after cardioversion to sinus rhythm', 'volume': '94', 'author': 'Choy AMJ', 'year': '1996', 'journal-title': 'Circulation'} / Circulation / Increased sensitivity to QT prolonging drug therapy immediately after cardioversion to sinus rhythm by Choy AMJ (1996)
10.1161/01.RES.75.5.879
{'key': 'e_1_2_1_26_2', 'article-title': 'Diuretics potentiate monophasic action potential prolonging effects of class III antiarrhythmic drugs in isolated guinea pig hearts (abstract)', 'volume': '90', 'author': 'Turgeon J', 'year': '1994', 'journal-title': 'Circulation'} / Circulation / Diuretics potentiate monophasic action potential prolonging effects of class III antiarrhythmic drugs in isolated guinea pig hearts (abstract) by Turgeon J (1994)
10.1016/0002-9149(87)90634-5
10.1161/01.CIR.87.6.1866
10.1161/01.RES.73.5.857
10.1161/01.RES.72.1.75
10.1085/jgp.96.1.195 / J Gen Physiol / Two components of cardiac delayed rectifier K+ current: Differential sensitivity to block by class III antiarrhythmic agents by Sanguinetti MC (1990)
10.1001/jama.1993.03500120070028
10.1161/01.CIR.94.4.817
{'key': 'e_1_2_1_34_2', 'first-page': '220', 'article-title': 'Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro implications for proarrhythmic potential', 'volume': '282', 'author': 'Carlsson L', 'year': '1997', 'journal-title': 'J Pharmacol Exp Ther'} / J Pharmacol Exp Ther / Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro implications for proarrhythmic potential by Carlsson L (1997)
{'key': 'e_1_2_1_35_2', 'first-page': '99', 'article-title': 'Ibutilide, a new compound with potent class III antiarrhythmic activity, activates a slow inward Na+ current in guinea pig ventricular cells', 'volume': '262', 'author': 'Lee KS.', 'year': '1992', 'journal-title': 'J Pharmacol Exp Ther'} / J Pharmacol Exp Ther / Ibutilide, a new compound with potent class III antiarrhythmic activity, activates a slow inward Na+ current in guinea pig ventricular cells by Lee KS. (1992)
10.1161/01.CIR.91.6.1799
10.1161/01.CIR.93.3.407
{'key': 'e_1_2_1_38_2', 'first-page': '1554', 'article-title': 'Discordance between IKr block and torsades de pointes', 'volume': '96', 'author': 'Yang T', 'year': '1997', 'journal-title': 'Circulation'} / Circulation / Discordance between IKr block and torsades de pointes by Yang T (1997)
10.1016/0092-8674(95)90340-2
10.1093/cvr/27.12.2186
10.1001/jama.1990.03450210088038
10.1056/NEJM199607253350416
{'key': 'e_1_2_1_43_2', 'first-page': '551', 'article-title': 'Incidence, type, and dose‐dependence of proarrhythmic events during sotalol therapy in patients treated for sustained VT/VF', 'volume': '15', 'author': 'Hohnloser SH', 'year': '1992', 'journal-title': 'PACE'} / PACE / Incidence, type, and dose‐dependence of proarrhythmic events during sotalol therapy in patients treated for sustained VT/VF by Hohnloser SH (1992)
{'key': 'e_1_2_1_44_2', 'first-page': '690', 'article-title': 'Sex differences in the evolution of the electrocardiographic QT interval with age', 'volume': '8', 'author': 'Rautaharju PM', 'year': '1992', 'journal-title': 'Can J Cardiol'} / Can J Cardiol / Sex differences in the evolution of the electrocardiographic QT interval with age by Rautaharju PM (1992)
10.1161/01.RES.78.2.262
10.1016/1050-1738(93)90016-Y
10.1161/01.CIR.94.8.1996
{'key': 'e_1_2_1_48_2', 'first-page': 'I211', 'article-title': 'Identification of a long QT syndrome molecular defect in drug‐induced torsades de pointes', 'volume': '96', 'author': 'Napolitano C', 'year': '1997', 'journal-title': 'Circulation'} / Circulation / Identification of a long QT syndrome molecular defect in drug‐induced torsades de pointes by Napolitano C (1997)
{'key': 'e_1_2_1_49_2', 'first-page': 'I‐211', 'article-title': 'Do mutations in cardiac ion channel genes predispose to drug‐induced (acquired) long QT syndrome', 'volume': '96', 'author': 'Schultz‐Bahr E', 'year': '1997', 'journal-title': 'Circulation'} / Circulation / Do mutations in cardiac ion channel genes predispose to drug‐induced (acquired) long QT syndrome by Schultz‐Bahr E (1997)

Dates

Type	When
Created	19 years, 2 months ago (July 2, 2006, 3:07 p.m.)
Deposited	1 year, 10 months ago (Oct. 28, 2023, 8:24 a.m.)
Indexed	2 weeks, 4 days ago (Aug. 19, 2025, 6:35 a.m.)
Issued	27 years, 4 months ago (May 1, 1998)
Published	27 years, 4 months ago (May 1, 1998)
Published Online	19 years, 2 months ago (June 30, 2006)
Published Print	27 years, 4 months ago (May 1, 1998)

Funders 0

None

BibTeX

@article{RODEN_1998, title={Taking the “Idio” out of “Idiosyncratic”: Predicting Torsades de Pointes}, volume={21}, ISSN={1540-8159}, url={http://dx.doi.org/10.1111/j.1540-8159.1998.tb00148.x}, DOI={10.1111/j.1540-8159.1998.tb00148.x}, number={5}, journal={Pacing and Clinical Electrophysiology}, publisher={Wiley}, author={RODEN, DAN M.}, year={1998}, month=may, pages={1029–1034} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        19
      ]
    ],
    "date-time": "2025-08-19T10:35:44Z",
    "timestamp": 1755599744858
  },
  "reference-count": 48,
  "publisher": "Wiley",
  "issue": "5",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2006,
            6,
            30
          ]
        ],
        "date-time": "2006-06-30T00:00:00Z",
        "timestamp": 1151625600000
      },
      "content-version": "vor",
      "delay-in-days": 2982,
      "URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1998,
        5
      ]
    ]
  },
  "DOI": "10.1111/j.1540-8159.1998.tb00148.x",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2006,
        7,
        2
      ]
    ],
    "date-time": "2006-07-02T19:07:33Z",
    "timestamp": 1151867253000
  },
  "page": "1029-1034",
  "source": "Crossref",
  "is-referenced-by-count": 552,
  "title": "Taking the \u201cIdio\u201d out of \u201cIdiosyncratic\u201d: Predicting Torsades de Pointes",
  "prefix": "10.1111",
  "volume": "21",
  "author": [
    {
      "given": "DAN M.",
      "family": "RODEN",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "311",
  "published-online": {
    "date-parts": [
      [
        2006,
        6,
        30
      ]
    ]
  },
  "reference": [
    {
      "key": "e_1_2_1_2_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.30.1.17"
    },
    {
      "key": "e_1_2_1_3_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1007/BF01778848"
    },
    {
      "key": "e_1_2_1_4_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.44.1.130"
    },
    {
      "key": "e_1_2_1_5_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0002-8703(86)90010-4"
    },
    {
      "key": "e_1_2_1_6_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1056/NEJM199407073310108"
    },
    {
      "key": "e_1_2_1_7_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0735-1097(96)00121-0"
    },
    {
      "key": "e_1_2_1_8_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.94.7.1613"
    },
    {
      "key": "e_1_2_1_9_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0140-6736(96)02149-6"
    },
    {
      "key": "e_1_2_1_10_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1136/hrt.48.3.213"
    },
    {
      "key": "e_1_2_1_11_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0735-1097(96)00377-4"
    },
    {
      "key": "e_1_2_1_12_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.RES.72.3.631"
    },
    {
      "key": "e_1_2_1_13_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.RES.79.3.474"
    },
    {
      "key": "e_1_2_1_14_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.86.5.1376"
    },
    {
      "key": "e_1_2_1_15_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1136/hrt.63.6.342"
    },
    {
      "key": "e_1_2_1_16_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0002-8703(84)90081-4"
    },
    {
      "key": "e_1_2_1_17_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1001/jama.1993.03510210076031"
    },
    {
      "key": "e_1_2_1_18_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/cvr/27.12.2186"
    },
    {
      "key": "e_1_2_1_19_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1111/j.1540-8159.1998.tb00150.x"
    },
    {
      "key": "e_1_2_1_20_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1136/hrt.32.1.57"
    },
    {
      "key": "e_1_2_1_21_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1002/clc.4960170410"
    },
    {
      "key": "e_1_2_1_22_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1136/pgmj.68.798.289"
    },
    {
      "key": "e_1_2_1_23_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0735-1097(95)00286-5"
    },
    {
      "key": "e_1_2_1_24_2",
      "first-page": "1202",
      "article-title": "Increased sensitivity to QT prolonging drug therapy immediately after cardioversion to sinus rhythm",
      "volume": "94",
      "author": "Choy AMJ",
      "year": "1996",
      "journal-title": "Circulation"
    },
    {
      "key": "e_1_2_1_25_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.RES.75.5.879"
    },
    {
      "key": "e_1_2_1_26_2",
      "article-title": "Diuretics potentiate monophasic action potential prolonging effects of class III antiarrhythmic drugs in isolated guinea pig hearts (abstract)",
      "volume": "90",
      "author": "Turgeon J",
      "year": "1994",
      "journal-title": "Circulation"
    },
    {
      "key": "e_1_2_1_27_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0002-9149(87)90634-5"
    },
    {
      "key": "e_1_2_1_28_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.87.6.1866"
    },
    {
      "key": "e_1_2_1_29_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.RES.73.5.857"
    },
    {
      "key": "e_1_2_1_30_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.RES.72.1.75"
    },
    {
      "key": "e_1_2_1_31_2",
      "doi-asserted-by": "crossref",
      "first-page": "195",
      "DOI": "10.1085/jgp.96.1.195",
      "article-title": "Two components of cardiac delayed rectifier K+ current: Differential sensitivity to block by class III antiarrhythmic agents",
      "volume": "96",
      "author": "Sanguinetti MC",
      "year": "1990",
      "journal-title": "J Gen Physiol"
    },
    {
      "key": "e_1_2_1_32_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1001/jama.1993.03500120070028"
    },
    {
      "key": "e_1_2_1_33_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.94.4.817"
    },
    {
      "key": "e_1_2_1_34_2",
      "first-page": "220",
      "article-title": "Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro implications for proarrhythmic potential",
      "volume": "282",
      "author": "Carlsson L",
      "year": "1997",
      "journal-title": "J Pharmacol Exp Ther"
    },
    {
      "key": "e_1_2_1_35_2",
      "first-page": "99",
      "article-title": "Ibutilide, a new compound with potent class III antiarrhythmic activity, activates a slow inward Na+ current in guinea pig ventricular cells",
      "volume": "262",
      "author": "Lee KS.",
      "year": "1992",
      "journal-title": "J Pharmacol Exp Ther"
    },
    {
      "key": "e_1_2_1_36_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.91.6.1799"
    },
    {
      "key": "e_1_2_1_37_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.93.3.407"
    },
    {
      "key": "e_1_2_1_38_2",
      "first-page": "1554",
      "article-title": "Discordance between IKr block and torsades de pointes",
      "volume": "96",
      "author": "Yang T",
      "year": "1997",
      "journal-title": "Circulation"
    },
    {
      "key": "e_1_2_1_39_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(95)90340-2"
    },
    {
      "key": "e_1_2_1_40_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1093/cvr/27.12.2186"
    },
    {
      "key": "e_1_2_1_41_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1001/jama.1990.03450210088038"
    },
    {
      "key": "e_1_2_1_42_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1056/NEJM199607253350416"
    },
    {
      "key": "e_1_2_1_43_2",
      "first-page": "551",
      "article-title": "Incidence, type, and dose\u2010dependence of proarrhythmic events during sotalol therapy in patients treated for sustained VT/VF",
      "volume": "15",
      "author": "Hohnloser SH",
      "year": "1992",
      "journal-title": "PACE"
    },
    {
      "key": "e_1_2_1_44_2",
      "first-page": "690",
      "article-title": "Sex differences in the evolution of the electrocardiographic QT interval with age",
      "volume": "8",
      "author": "Rautaharju PM",
      "year": "1992",
      "journal-title": "Can J Cardiol"
    },
    {
      "key": "e_1_2_1_45_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.RES.78.2.262"
    },
    {
      "key": "e_1_2_1_46_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/1050-1738(93)90016-Y"
    },
    {
      "key": "e_1_2_1_47_2",
      "doi-asserted-by": "publisher",
      "DOI": "10.1161/01.CIR.94.8.1996"
    },
    {
      "key": "e_1_2_1_48_2",
      "first-page": "I211",
      "article-title": "Identification of a long QT syndrome molecular defect in drug\u2010induced torsades de pointes",
      "volume": "96",
      "author": "Napolitano C",
      "year": "1997",
      "journal-title": "Circulation"
    },
    {
      "key": "e_1_2_1_49_2",
      "first-page": "I\u2010211",
      "article-title": "Do mutations in cardiac ion channel genes predispose to drug\u2010induced (acquired) long QT syndrome",
      "volume": "96",
      "author": "Schultz\u2010Bahr E",
      "year": "1997",
      "journal-title": "Circulation"
    }
  ],
  "container-title": "Pacing and Clinical Electrophysiology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1540-8159.1998.tb00148.x",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1540-8159.1998.tb00148.x",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        10,
        28
      ]
    ],
    "date-time": "2023-10-28T12:24:35Z",
    "timestamp": 1698495875000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://onlinelibrary.wiley.com/doi/10.1111/j.1540-8159.1998.tb00148.x"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1998,
        5
      ]
    ]
  },
  "references-count": 48,
  "journal-issue": {
    "issue": "5",
    "published-print": {
      "date-parts": [
        [
          1998,
          5
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1111/j.1540-8159.1998.tb00148.x"
  ],
  "URL": "http://dx.doi.org/10.1111/j.1540-8159.1998.tb00148.x",
  "relation": {},
  "ISSN": [
    "0147-8389",
    "1540-8159"
  ],
  "subject": [],
  "container-title-short": "Pacing Clinical Electrophis",
  "published": {
    "date-parts": [
      [
        1998,
        5
      ]
    ]
  }
}