DOI: 10.1111/j.1528-1157.1992.tb06223.x. Status Epilepticus in Children, Adults, and the Elderly

Status Epilepticus in Children, Adults, and the Elderly

10.1111/j.1528-1157.1992.tb06223.x

Crossref journal-article

Wiley

Epilepsia (311)

Abstract

Summary: Status epilepticus (SE) is a major neurological and medical emergency associated with a high morbidity and mortality. Retrospective and prospective studies from the Medical College of Virginia Epilepsy Research Center have been utilized to investigate several clinical and epidemiological factors associated with SE. Univariate and multivariate logistic regression analysis of predictive indicators in patients with SE indicated that seizure duration, certain specific etiologies, and age were predictors of mortality. Sex, race, and certain other etiologies were not found to be factors that significantly affect mortality. These findings demonstrate that specific indicators are important in predicting mortality in SE. Preliminary prospective epidemiological data from Richmond, Virginia suggested that more than 250,000 cases of SE may occur annually in the United States with a mortality greater than 55,000 individuals. Studies comparing community and university hospitals in Richmond indicate that the mortality and clinical variables associated with SE in these two hospital populations are essentially identical. Further investigations employing prospective population‐based studies are essential in evaluating the epidemiology and mortality of SE.

Bibliography

DeLorenzo, R. J., Towne, A. R., Pellock, J. M., & Ko, D. (1992). Status Epilepticus in Children, Adults, and the Elderly. Epilepsia, 33(s4), 15â25. Portico.

Authors 4

Robert J. DeLorenzo (first)
Alan R. Towne (additional)
John M. Pellock (additional)
Daijin Ko (additional)

References 45 Referenced 184

10.1111/j.1528-1157.1970.tb03880.x
{'key': 'e_1_2_1_3_1', 'first-page': '115', 'volume-title': 'Status epilepticus: mechanisms of brain damage and treatment', 'author': 'Aicardi J.', 'year': '1983'} / Status epilepticus: mechanisms of brain damage and treatment by Aicardi J. (1983)
10.1016/0002-9343(80)90415-5
{'key': 'e_1_2_1_5_1', 'first-page': '519', 'article-title': 'Antecedents, precipitants and prognosis of patients with status epilepticus [Abstract]', 'volume': '24', 'author': 'Barry E.', 'year': '1983', 'journal-title': 'Epilepsia'} / Epilepsia / Antecedents, precipitants and prognosis of patients with status epilepticus [Abstract] by Barry E. (1983)
{'key': 'e_1_2_1_6_1', 'volume-title': "Eulenberg's realencyclopadie", 'author': 'Binswanger O.', 'year': '1886'} / Eulenberg's realencyclopadie by Binswanger O. (1886)
{'key': 'e_1_2_1_7_1', 'first-page': '203', 'article-title': 'Therapeutic problems related to tonic status epilepticus', 'volume': '14', 'author': 'Bladin PF', 'year': '1977', 'journal-title': 'Clin Exp Neurol'} / Clin Exp Neurol / Therapeutic problems related to tonic status epilepticus by Bladin PF (1977)
10.1016/0022-510X(66)90039-6
{'key': 'e_1_2_1_9_1', 'first-page': '19', 'article-title': 'Notes on epilepsy and its pathological consequences. J Ment Sci', 'volume': '19', 'author': 'Browne JC.', 'year': '1873', 'journal-title': 'Am J Insan'} / Am J Insan / Notes on epilepsy and its pathological consequences. J Ment Sci by Browne JC. (1873)
10.1001/archneur.1988.00520310099023
{'key': 'e_1_2_1_11_1', 'first-page': '55', 'volume-title': 'Status epilepticus: mechanisms of brain damage and treatment', 'author': 'Celesia GG.', 'year': '1983'} / Status epilepticus: mechanisms of brain damage and treatment by Celesia GG. (1983)
10.1056/NEJM198206033062205
{'key': 'e_1_2_1_13_1', 'volume-title': 'Status epilepticus: mechanisms of brain damage and treatment', 'author': 'Delgado‐Escueta AV', 'year': '1983'} / Status epilepticus: mechanisms of brain damage and treatment by Delgado‐Escueta AV (1983)
{'key': 'e_1_2_1_14_1', 'first-page': '132', 'article-title': 'Mortality and seizure duration in status epilepticus [Abstract]', 'volume': '22', 'author': 'DeLorenzo RJ', 'year': '1987', 'journal-title': 'Ann Neurol'} / Ann Neurol / Mortality and seizure duration in status epilepticus [Abstract] by DeLorenzo RJ (1987)
10.1055/s-2008-1063984
{'key': 'e_1_2_1_16_1', 'first-page': '47', 'volume-title': 'Current therapy in neurologic disease', 'author': 'DeLorenzo RJ.', 'year': '1990'} / Current therapy in neurologic disease by DeLorenzo RJ. (1990)
{'key': 'e_1_2_1_17_1', 'first-page': '250', 'volume-title': 'Neurological and electroencephalographical studies in infancy', 'author': 'Dreyfus‐Brisac C.', 'year': '1964'} / Neurological and electroencephalographical studies in infancy by Dreyfus‐Brisac C. (1964)
10.1177/088307388800300303
{'key': 'e_1_2_1_19_1', 'first-page': '112', 'volume-title': 'Seizures and epilepsy', 'author': 'Engel J.', 'year': '1989'} / Seizures and epilepsy by Engel J. (1989)
{'key': 'e_1_2_1_20_1', 'first-page': 'S2', 'volume': '10', 'author': 'Gastaut H.', 'year': '1969', 'journal-title': 'Epilepsia'} / Epilepsia by Gastaut H. (1969)
{'key': 'e_1_2_1_21_1', 'first-page': '15', 'volume-title': 'Status epilepticus: mechanisms of brain damage and treatment', 'author': 'Gastaut H.', 'year': '1983'} / Status epilepticus: mechanisms of brain damage and treatment by Gastaut H. (1983)
{'key': 'e_1_2_1_22_1', 'volume-title': 'Definitions', 'author': 'Gastaut H.', 'year': '1973'} / Definitions by Gastaut H. (1973)
{'key': 'e_1_2_1_23_1', 'volume-title': 'Epilepsy and other chronic convulsive diseases', 'author': 'Gowers WRG.', 'year': '1901'} / Epilepsy and other chronic convulsive diseases by Gowers WRG. (1901)
{'key': 'e_1_2_1_24_1', 'first-page': '3', 'volume-title': 'Status epilepticus: mechanisms of brain damage and treatment', 'author': 'Hauser WA.', 'year': '1983'} / Status epilepticus: mechanisms of brain damage and treatment by Hauser WA. (1983)
{'issue': '2', 'key': 'e_1_2_1_25_1', 'first-page': '9', 'article-title': 'Status epilepticus: epidemiological considerations', 'volume': '40', 'author': 'Hauser WA.', 'year': '1990', 'journal-title': 'Neurology'} / Neurology / Status epilepticus: epidemiological considerations by Hauser WA. (1990)
{'key': 'e_1_2_1_26_1', 'volume-title': 'Status epilepticus: etiology, clinical aspects and lethality', 'author': 'Heintel H.', 'year': '1972'} / Status epilepticus: etiology, clinical aspects and lethality by Heintel H. (1972)
10.1111/j.1528-1157.1959.tb04257.x
10.1111/j.1528-1157.1942.tb00409.x
{'key': 'e_1_2_1_29_1', 'first-page': '272', 'article-title': 'Status epilepticus', 'volume': '7', 'author': 'Leppik IE.', 'year': '1985', 'journal-title': 'Clin Ther'} / Clin Ther / Status epilepticus by Leppik IE. (1985)
{'key': 'e_1_2_1_30_1', 'first-page': '3', 'article-title': 'Diagnosis and treatment of status epilepticus', 'volume': '4', 'author': 'Leppik IE.', 'year': '1987', 'journal-title': 'Merritt Putnam Q'} / Merritt Putnam Q / Diagnosis and treatment of status epilepticus by Leppik IE. (1987)
{'issue': '2', 'key': 'e_1_2_1_31_1', 'first-page': 'S4', 'article-title': 'Status epilepticus: the next decade', 'volume': '40', 'author': 'Leppik IE.', 'year': '1990', 'journal-title': 'Neurology'} / Neurology / Status epilepticus: the next decade by Leppik IE. (1990)
{'key': 'e_1_2_1_32_1', 'volume-title': 'Status epilepticus', 'author': 'Lorenz C.', 'year': '1890'} / Status epilepticus by Lorenz C. (1890)
10.1542/peds.83.3.323
{'key': 'e_1_2_1_34_1', 'first-page': '261', 'volume-title': 'Status epilepticus: mechanisms of brain damage and treatment', 'author': 'Meldrum BS.', 'year': '1983'} / Status epilepticus: mechanisms of brain damage and treatment by Meldrum BS. (1983)
10.1001/archneur.1973.00490190028002
10.1093/brain/97.1.407
10.1136/jnnp.34.2.182
10.1111/j.1600-0404.1970.tb05814.x
10.1007/978-1-4612-1017-7
10.1111/j.1528-1157.1985.tb05725.x
10.1002/ana.410090508
{'issue': '1', 'key': 'e_1_2_1_42_1', 'first-page': '104', 'article-title': 'Cerebrospinal fluid findings in prolonged status epilepticus', 'volume': '37', 'author': 'Towne AR', 'year': '1987', 'journal-title': 'Neurology'} / Neurology / Cerebrospinal fluid findings in prolonged status epilepticus by Towne AR (1987)
{'issue': '1', 'key': 'e_1_2_1_43_1', 'first-page': '299', 'article-title': 'Mortality in a community‐based status epilepticus study', 'volume': '40', 'author': 'Towne AR', 'year': '1990', 'journal-title': 'Neurology'} / Neurology / Mortality in a community‐based status epilepticus study by Towne AR (1990)
{'key': 'e_1_2_1_44_1', 'article-title': 'Determinants of mortality in status epilepticus', 'author': 'Towne AR', 'year': '1993', 'journal-title': 'Epilepsia'} / Epilepsia / Determinants of mortality in status epilepticus by Towne AR (1993)
{'issue': '2', 'key': 'e_1_2_1_45_1', 'first-page': '32', 'article-title': 'The role of benzodiazepines in the management of status epilepticus', 'volume': '40', 'author': 'Treiman DM.', 'year': '1990', 'journal-title': 'Neurology'} / Neurology / The role of benzodiazepines in the management of status epilepticus by Treiman DM. (1990)
{'key': 'e_1_2_1_46_1', 'first-page': '101', 'volume-title': 'Epilepsy', 'author': 'Turner WA.', 'year': '1907'} / Epilepsy by Turner WA. (1907)

Dates

Type	When
Created	16 years, 9 months ago (Dec. 2, 2008, 11:42 a.m.)
Deposited	1 year, 11 months ago (Sept. 26, 2023, 5:41 p.m.)
Indexed	1 month, 3 weeks ago (July 11, 2025, 6:43 a.m.)
Issued	33 years, 2 months ago (July 1, 1992)
Published	33 years, 2 months ago (July 1, 1992)
Published Online	16 years, 9 months ago (Dec. 2, 2008)
Published Print	33 years, 2 months ago (July 1, 1992)

Funders 0

None

BibTeX

@article{DeLorenzo_1992, title={Status Epilepticus in Children, Adults, and the Elderly}, volume={33}, ISSN={1528-1167}, url={http://dx.doi.org/10.1111/j.1528-1157.1992.tb06223.x}, DOI={10.1111/j.1528-1157.1992.tb06223.x}, number={s4}, journal={Epilepsia}, publisher={Wiley}, author={DeLorenzo, Robert J. and Towne, Alan R. and Pellock, John M. and Ko, Daijin}, year={1992}, month=jul, pages={15–25} }

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