DOI: 10.1111/j.1476-5381.1975.tb07364.x. KINETICS OF AGONIST CONDUCTANCE CHANGES DURING HYPERPOLARIZATION AT FROG ENDPLATES

KINETICS OF AGONIST CONDUCTANCE CHANGES DURING HYPERPOLARIZATION AT FROG ENDPLATES

10.1111/j.1476-5381.1975.tb07364.x

Crossref journal-article

Wiley

British Journal of Pharmacology (311)

Abstract

The effect of rapid hyperpolarization on acetylcholine‐ or carbachol‐induced currents was studied at voltage clamped frog endplates. Following a hyperpolarizing step the agonist‐induced conductance increased approximately exponentially to a new level. The rate constant for this process was smaller during hyperpolarization or lowered temperature, and was also smaller for acetylcholine than for carbachol. The results are interpreted in terms of a potential‐ dependent conformational change of the receptor.

Bibliography

ADAMS, P. R. (1975). KINETICS OF AGONIST CONDUCTANCE CHANGES DURING HYPERPOLARIZATION AT FROG ENDPLATES. British Journal of Pharmacology, 53(2), 308â310. Portico.

Authors 1

P.R. ADAMS (first)

References 5 Referenced 51

Dates

Type	When
Created	13 years, 1 month ago (July 19, 2012, 2:45 p.m.)
Deposited	1 year, 9 months ago (Nov. 4, 2023, 5:36 p.m.)
Indexed	1 year, 2 months ago (June 17, 2024, 3:58 p.m.)
Issued	50 years, 7 months ago (Feb. 1, 1975)
Published	50 years, 7 months ago (Feb. 1, 1975)
Published Online	13 years, 1 month ago (July 19, 2012)
Published Print	50 years, 7 months ago (Feb. 1, 1975)

Funders 0

None

BibTeX

@article{ADAMS_1975, title={KINETICS OF AGONIST CONDUCTANCE CHANGES DURING HYPERPOLARIZATION AT FROG ENDPLATES}, volume={53}, ISSN={1476-5381}, url={http://dx.doi.org/10.1111/j.1476-5381.1975.tb07364.x}, DOI={10.1111/j.1476-5381.1975.tb07364.x}, number={2}, journal={British Journal of Pharmacology}, publisher={Wiley}, author={ADAMS, P.R.}, year={1975}, month=feb, pages={308–310} }

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