DOI: 10.1111/j.1471-4159.1985.tb12869.x. Immunohistochemical Localization of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and Myelin Basic Protein in the Central Nervous System of the <i>Jimpy</i> and the Normal Mouse

Immunohistochemical Localization of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and Myelin Basic Protein in the Central Nervous System of the Jimpy and the Normal Mouse

10.1111/j.1471-4159.1985.tb12869.x

Crossref journal-article

Wiley

Journal of Neurochemistry (311)

Abstract

Abstract: We describe the immunohistochemical localization of 2′,3′‐cyclic nucleotide 3′‐phosphodiesterase (CNPase) and myelin basic protein (MBP) in CNS of the jimpy mutant mouse which is characterized by dys‐ and demyelination. In controls, the CNPase and MBP were localized exclusively in white matter in the CNS. The jimpy mutant mice were severely affected: A very weak reaction was observed in the white matter. Very few CNPase‐ and MBP‐positive myelin sheaths were observed, and some degradation products were also observed after reaction with antisera against both CNPase and MBP. The immunohistochemical reaction in the jimpy mice showed a similar localization in both CNPase and MBP.

Bibliography

Mikoshiba, K., Kohsaka, S., Hayakawa, T., Takamatsu, K., & Tsukada, Y. (1985). Immunohistochemical Localization of 2â²,3â²âCyclic Nucleotide 3â²âPhosphodiesterase and Myelin Basic Protein in the Central Nervous System of the Jimpy and the Normal Mouse. Journal of Neurochemistry, 44(3), 686â691. Portico.

Authors 5

Katsuhiko Mikoshiba (first)
Shinichi Kohsaka (additional)
Taketoshi Hayakawa (additional)
Ken Takamatsu (additional)
Yasuzo Tsukada (additional)

References 29 Referenced 12

10.1016/S0021-9258(17)33540-8 / J. Biol. Chem. / Basis of microheterogeneity of myelin basic protein by Chou F. C. H. (1976)
10.1111/j.1471-4159.1979.tb05257.x
10.1016/S0021-9258(19)70852-7 / J. Bioi. Chem. / Hydrolysis of ribonucleoside 2′,3′‐cyclic phosphates by a diesterase from brain by Drummond G. I. (1962)
10.1111/j.1471-4159.1978.tb00122.x
10.1016/0304-3940(79)91490-3
{'key': 'e_1_2_2_7_1', 'first-page': '327', 'volume-title': 'Neurological Mutations Affecting Myelination', 'author': 'Dupouey P.', 'year': '1980'} / Neurological Mutations Affecting Myelination by Dupouey P. (1980)
10.1016/0006-8993(81)90269-9
10.1111/j.1471-4159.1983.tb04760.x
10.1111/j.1471-4159.1967.tb06164.x
10.1016/0006-8993(69)90299-6
10.1111/j.1471-4159.1970.tb02252.x
10.1016/S0021-9258(19)52451-6
{'key': 'e_1_2_2_14_1', 'first-page': '200', 'article-title': 'Correlation of 2′,3′‐cyclic nucleotide 3′‐phosphohydrolase activity and the dysmyelination in the nervous system from the shiverer mutant mice', 'volume': '18', 'author': 'Mikoshiba K.', 'year': '1979', 'journal-title': 'Bull. Jpn. Neurochem. Soc.'} / Bull. Jpn. Neurochem. Soc. / Correlation of 2′,3′‐cyclic nucleotide 3′‐phosphohydrolase activity and the dysmyelination in the nervous system from the shiverer mutant mice by Mikoshiba K. (1979)
10.1016/0006-8993(79)90780-7
10.1016/0006-8993(80)91019-7
{'key': 'e_1_2_2_17_1', 'first-page': '349', 'volume-title': 'Neurological Mutation Affecting Myelination', 'author': 'Mikoshiba K.', 'year': '1980'} / Neurological Mutation Affecting Myelination by Mikoshiba K. (1980)
10.1111/j.1471-4159.1980.tb06288.x
10.1007/978-3-642-49323-2_17
{'key': 'e_1_2_2_20_1', 'first-page': '48', 'article-title': 'Neurochemical studies on the myelin‐deficient twitcher mutant mice', 'volume': '22', 'author': 'Mikoshiba K.', 'year': '1983', 'journal-title': 'Bull. Jpn. Neurochem. Soc.'} / Bull. Jpn. Neurochem. Soc. / Neurochemical studies on the myelin‐deficient twitcher mutant mice by Mikoshiba K. (1983)
10.1007/BF00965887
10.1111/j.1471-4159.1981.tb10826.x
10.1111/j.1471-4159.1981.tb04482.x
10.1016/0006-8993(81)90055-X
10.1016/0006-8993(82)90759-4
10.1016/0304-3940(79)91489-7
10.1021/ja01556a015
10.1111/j.1471-4159.1983.tb00878.x
10.1111/j.1471-4159.1980.tb09669.x
10.1111/j.1471-4159.1980.tb09680.x

Dates

Type	When
Created	18 years, 8 months ago (Dec. 13, 2006, 7:10 a.m.)
Deposited	1 year, 10 months ago (Oct. 20, 2023, 11:42 a.m.)
Indexed	2 months, 3 weeks ago (June 12, 2025, 5:27 a.m.)
Issued	40 years, 6 months ago (March 1, 1985)
Published	40 years, 6 months ago (March 1, 1985)
Published Online	18 years, 8 months ago (Dec. 12, 2006)
Published Print	40 years, 6 months ago (March 1, 1985)

Funders 0

None

BibTeX

@article{Mikoshiba_1985, title={Immunohistochemical Localization of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and Myelin Basic Protein in the Central Nervous System of the Jimpy and the Normal Mouse}, volume={44}, ISSN={1471-4159}, url={http://dx.doi.org/10.1111/j.1471-4159.1985.tb12869.x}, DOI={10.1111/j.1471-4159.1985.tb12869.x}, number={3}, journal={Journal of Neurochemistry}, publisher={Wiley}, author={Mikoshiba, Katsuhiko and Kohsaka, Shinichi and Hayakawa, Taketoshi and Takamatsu, Ken and Tsukada, Yasuzo}, year={1985}, month=mar, pages={686–691} }

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