Abstract
Abstract—Alkanes, a new class of neurolipid, were found in mouse brain, the level being reduced in the Quaking mutant. These hydrocarbons are concentrated in myelin; minor amounts being found in microsomes, mitochondria and synaptosomes. The average recovery is 7.1 μg/mg in normal myelin, 2.2 in the Quaking myelin. The distribution pattern of these alkanes was determined by gas liquid chromatography and was found to differ in normal and Quaking myelin; the hydrocarbons consist mainly of n‐alkanes ranging from C21 to C32 with even and odd aliphatic chains.
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Dates
Type | When |
---|---|
Created | 18 years, 11 months ago (Oct. 5, 2006, 3:35 a.m.) |
Deposited | 1 year, 10 months ago (Nov. 4, 2023, 3:32 p.m.) |
Indexed | 1 year, 10 months ago (Nov. 4, 2023, 4:10 p.m.) |
Issued | 47 years, 11 months ago (Oct. 1, 1977) |
Published | 47 years, 11 months ago (Oct. 1, 1977) |
Published Online | 18 years, 11 months ago (Oct. 4, 2006) |
Published Print | 47 years, 11 months ago (Oct. 1, 1977) |
@article{BOURRE_1977, title={OCCURRENCE OF ALKANES IN BRAIN MYELIN. COMPARISON BETWEEN NORMAL AND QUAKING MOUSE}, volume={29}, ISSN={1471-4159}, url={http://dx.doi.org/10.1111/j.1471-4159.1977.tb07781.x}, DOI={10.1111/j.1471-4159.1977.tb07781.x}, number={4}, journal={Journal of Neurochemistry}, publisher={Wiley}, author={BOURRE, J. M. and CASSAGNE, C. and LARROUQUERE‐REGNIER, S. and DARRIET, D.}, year={1977}, month=oct, pages={645–648} }