DOI: 10.1111/j.1471-4159.1972.tb01474.x. COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION

COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION

10.1111/j.1471-4159.1972.tb01474.x

Crossref journal-article

Wiley

Journal of Neurochemistry (311)

Abstract

Abstract— trans‐4‐aminocrotonic acid, dl‐cis‐aminocyclohexane‐ltarboxylic acid and 4‐aminotetrolic acid were found to be competitive inhibitors of GABA uptake in rat brain slices. These inhibitors are analogues of extended conformations of GABA, which indicates that these conformations are important in the initial binding of this inhibitory transmitter to its transport carrier.

Bibliography

Beart, P. M., Johnston, G. A. R., & Urn, M. L. (1972). COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION. Journal of Neurochemistry, 19(8), 1855â1861. Portico.

Authors 3

P. M. Beart (first)
G. A. R. Johnston (additional)
M. L. Urn (additional)

References 14 Referenced 99

10.1038/newbio234080a0
10.1071/CH9721359
10.1111/j.1471-4159.1972.tb01473.x
10.1016/0926-6569(63)90211-6
10.1038/198463a0
10.1038/newbio233232a0
{'key': 'e_1_2_1_8_1', 'first-page': '115', 'volume': '4', 'author': 'Curtis D. R.', 'year': '1970', 'journal-title': 'Handbook of Neurochemistry'} / Handbook of Neurochemistry by Curtis D. R. (1970)
HewgillF. R.andJefferiesP. R.(1955)J. chem. Soc.2767. (10.1039/JR9550002767)
10.1111/j.1471-4159.1971.tb09600.x
10.1111/j.1471-4159.1968.tb06831.x
10.1007/BF00401785
10.1021/ja01633a018
10.1515/bchm2.1954.297.1.71
10.1042/bj0800324

Dates

Type	When
Created	18 years, 10 months ago (Oct. 4, 2006, 11:20 p.m.)
Deposited	1 year, 9 months ago (Nov. 4, 2023, 4:04 p.m.)
Indexed	3 months, 3 weeks ago (May 7, 2025, 7:32 a.m.)
Issued	53 years, 1 month ago (Aug. 1, 1972)
Published	53 years, 1 month ago (Aug. 1, 1972)
Published Online	18 years, 10 months ago (Oct. 4, 2006)
Published Print	53 years, 1 month ago (Aug. 1, 1972)

Funders 0

None

BibTeX

@article{Beart_1972, title={COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION}, volume={19}, ISSN={1471-4159}, url={http://dx.doi.org/10.1111/j.1471-4159.1972.tb01474.x}, DOI={10.1111/j.1471-4159.1972.tb01474.x}, number={8}, journal={Journal of Neurochemistry}, publisher={Wiley}, author={Beart, P. M. and Johnston, G. A. R. and Urn, M. L.}, year={1972}, month=aug, pages={1855–1861} }

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