DOI: 10.1111/j.1471-4159.1971.tb00181.x. PROTEIN DEGRADATION IN SQUID GIANT AXONS

PROTEIN DEGRADATION IN SQUID GIANT AXONS

10.1111/j.1471-4159.1971.tb00181.x

Crossref journal-article

Wiley

Journal of Neurochemistry (311)

Abstract

Abstract—Axoplasm extruded from giant axons of the Chilean squid, Dosidicus gigas, contained a low level of neutral proteinase‐like activity, equivalent to 4 × 10−6 mg of chymotrypsin per mg of axoplasmic protein. The enzyme was active at physiological pH and ionic strength. Activity was completely inhibited by 1 mM‐para‐hydroxymercuribenzoate and was enhanced by divalent metal cations, especially Ca2+. Axoplasm also exhibited proteinase activity at pH 4.8. Both neutral and acid proteinase like activities were also present in the axonal sheath containing Schwann cells, but their specific activities relative to those in the axoplasm were different. A physiological role, related to the axoplasmic flow of protein, is discussed for the axoplasmic neutral proteinase‐like activity.

Bibliography

Orrego, F. (1971). PROTEIN DEGRADATION IN SQUID GIANT AXONS. Journal of Neurochemistry, 18(12), 2249â2254. Portico.

Authors 1

F. Orrego (first)

References 33 Referenced 28

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Dates

Type	When
Created	18 years, 10 months ago (Oct. 4, 2006, 10:42 p.m.)
Deposited	1 year, 9 months ago (Nov. 4, 2023, 5:16 p.m.)
Indexed	1 year, 9 months ago (Nov. 22, 2023, 6:28 p.m.)
Issued	53 years, 8 months ago (Dec. 1, 1971)
Published	53 years, 8 months ago (Dec. 1, 1971)
Published Online	18 years, 10 months ago (Oct. 4, 2006)
Published Print	53 years, 8 months ago (Dec. 1, 1971)

Funders 0

None

BibTeX

@article{Orrego_1971, title={PROTEIN DEGRADATION IN SQUID GIANT AXONS}, volume={18}, ISSN={1471-4159}, url={http://dx.doi.org/10.1111/j.1471-4159.1971.tb00181.x}, DOI={10.1111/j.1471-4159.1971.tb00181.x}, number={12}, journal={Journal of Neurochemistry}, publisher={Wiley}, author={Orrego, F.}, year={1971}, month=dec, pages={2249–2254} }

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