DOI: 10.1111/j.1469-7793.2000.t01-2-00011.x. Regulation of neuronal function by protein trafficking: a role for the endosomal pathway

Regulation of neuronal function by protein trafficking: a role for the endosomal pathway

10.1111/j.1469-7793.2000.t01-2-00011.x

Crossref journal-article

Wiley

The Journal of Physiology (311)

Abstract

Protein trafficking plays a central role in many aspects of neuronal function, from the release of neurotransmitters by exocytosis and the recycling of synaptic vesicle proteins to the regulation of receptor signalling. Synaptic function can be significantly modified on a short time scale by alterations in the levels of receptors, ion channels and transporters both pre‐ and postsynaptically. In many cases, these alterations appear to be mediated by acute changes in the rates at which the proteins are endocytosed from and exocytosed to the cell surface from intracellular pools. While our current understanding of the signalling mechanisms and the intracellular pathways responsible for these acute changes is still in its infancy, intriguing details are beginning to emerge from a number of systems.

Bibliography

Buckley, K. M., Melikian, H. E., Provoda, C. J., & Waring, M. T. (2000). Regulation of neuronal function by protein trafficking: a role for the endosomal pathway. The Journal of Physiology, 525(1), 11â19. Portico.

Authors 4

Kathleen M. Buckley (first)
Haley E. Melikian (additional)
Chester J. Provoda (additional)
Michael T. Waring (additional)

References 62 Referenced 47

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Dates

Type	When
Created	21 years ago (Aug. 13, 2004, 4:52 a.m.)
Deposited	1 year, 11 months ago (Sept. 4, 2023, 12:25 a.m.)
Indexed	4 months, 3 weeks ago (March 30, 2025, 6:04 p.m.)
Issued	25 years, 3 months ago (May 1, 2000)
Published	25 years, 3 months ago (May 1, 2000)
Published Online	25 years, 3 months ago (May 1, 2000)
Published Print	25 years, 3 months ago (May 1, 2000)

Funders 0

None

BibTeX

@article{Buckley_2000, title={Regulation of neuronal function by protein trafficking: a role for the endosomal pathway}, volume={525}, ISSN={1469-7793}, url={http://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00011.x}, DOI={10.1111/j.1469-7793.2000.t01-2-00011.x}, number={1}, journal={The Journal of Physiology}, publisher={Wiley}, author={Buckley, Kathleen M. and Melikian, Haley E. and Provoda, Chester J. and Waring, Michael T.}, year={2000}, month=may, pages={11–19} }

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