Abstract
AbstractThe formation of morphologically and functionally mature dendrites is a key event in neuronal maturation and the establishment of functional neuronal networks, but the signals that regulate mammalian dendritic development remain poorly understood. Here we show that the erbB receptor signalling pathway, which modulates expression of several neurotransmitter receptors, also regulates dendritic development of cerebellar granule cells in the intact cerebellum. These results suggest that neuregulin–erbB signalling may control a program of postsynaptic development, from initiating dendrite morphogenesis to the formation and maturation of the postsynaptic apparatus.
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Dates
Type | When |
---|---|
Created | 19 years, 4 months ago (April 21, 2006, 7:39 a.m.) |
Deposited | 1 year, 10 months ago (Oct. 9, 2023, 12:30 p.m.) |
Indexed | 1 year ago (Aug. 22, 2024, 3:10 a.m.) |
Issued | 19 years, 5 months ago (April 1, 2006) |
Published | 19 years, 5 months ago (April 1, 2006) |
Published Online | 19 years, 4 months ago (April 21, 2006) |
Published Print | 19 years, 5 months ago (April 1, 2006) |
@article{Rieff_2006, title={ErbB receptor signalling regulates dendrite formation in mouse cerebellar granule cells in vivo}, volume={23}, ISSN={1460-9568}, url={http://dx.doi.org/10.1111/j.1460-9568.2006.04727.x}, DOI={10.1111/j.1460-9568.2006.04727.x}, number={8}, journal={European Journal of Neuroscience}, publisher={Wiley}, author={Rieff, Heather I. and Corfas, Gabriel}, year={2006}, month=apr, pages={2225–2229} }