DOI: 10.1111/j.1432-1033.1995.tb20813.x. Functional and Physical Interactions of Components of the Yeast Mitochondrial Inner‐Membrane Import Machinery (MIM)

Functional and Physical Interactions of Components of the Yeast Mitochondrial Inner‐Membrane Import Machinery (MIM)

10.1111/j.1432-1033.1995.tb20813.x

Crossref journal-article

Wiley

European Journal of Biochemistry (311)

Abstract

The essential mitochondrial inner‐membrane protein, Mim44, is involved in the translocation of pre‐proteins across the mitochondrial inner membrane. Two other putative components of this protein‐translocation system are the integral inner‐membrane proteins, Mim23 and Mim17. Here, we present genetic evidence for functional co‐operation of all three proteins. Furthermore, we show that Mim23 and Mim17 are associated in a protein complex that also contains two proteins of 55 kDa and 20 kDa. We speculate that this subcomplex forms the proteinaceous import channel of the inner‐membrane which transiently interacts with a less abundant peripheral complex of Mim44 and mitochondrial heat‐shock protein Hsp70.

Bibliography

Blom, J., Dekker, P. J. T., & Meijer, M. (1995). Functional and Physical Interactions of Components of the Yeast Mitochondrial InnerâMembrane Import Machinery (MIM). European Journal of Biochemistry, 232(1), 309â314. Portico.

Authors 3

Jolanda Blom (first)
Peter J. T. Dekker (additional)
Michiel Meijer (additional)

References 45 Referenced 44

10.1016/0092-8674(89)90762-9
10.1016/0092-8674(90)90244-9
10.1038/355084a0
10.1038/348610a0
10.1016/0092-8674(93)80050-O
10.1016/0014-5793(93)80107-6
10.1002/j.1460-2075.1983.tb01718.x
10.1038/348605a0
10.1002/j.1460-2075.1990.tb07517.x
10.1016/0014-5793(92)81345-M
10.1002/j.1460-2075.1993.tb06095.x
10.1002/j.1460-2075.1992.tb05446.x
10.1073/pnas.89.24.11930
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10.1038/371768a0
10.1073/pnas.91.26.12818
10.1016/0968-0004(94)90113-9
{'key': 'e_1_2_2_29_2', 'volume-title': 'Methods in yeast genetics', 'author': 'Sherman F.', 'year': '1986'} / Methods in yeast genetics by Sherman F. (1986)
{'key': 'e_1_2_2_30_2', 'volume-title': 'Molecular cloning, a laboratory manual', 'author': 'Sambrook J.', 'year': '1989'} / Molecular cloning, a laboratory manual by Sambrook J. (1989)
10.1073/pnas.76.3.1035
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10.1146/annurev.ge.21.120187.001355
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10.1002/j.1460-2075.1992.tb05612.x
10.1083/jcb.122.3.635
10.1002/j.1460-2075.1994.tb06612.x
{'key': 'e_1_2_2_46_2', 'volume-title': 'DNA repair and mutagenesis in yeast', 'author': 'Haynes R. H.', 'year': '1978'} / DNA repair and mutagenesis in yeast by Haynes R. H. (1978)

Dates

Type	When
Created	20 years, 5 months ago (March 4, 2005, 7:38 a.m.)
Deposited	1 year, 10 months ago (Oct. 16, 2023, 2:30 a.m.)
Indexed	4 weeks, 1 day ago (Aug. 5, 2025, 8:14 a.m.)
Issued	30 years, 1 month ago (Aug. 1, 1995)
Published	30 years, 1 month ago (Aug. 1, 1995)
Published Online	20 years, 6 months ago (March 3, 2005)
Published Print	30 years, 1 month ago (Aug. 1, 1995)

Funders 0

None

BibTeX

@article{Blom_1995, title={Functional and Physical Interactions of Components of the Yeast Mitochondrial Inner‐Membrane Import Machinery (MIM)}, volume={232}, ISSN={1432-1033}, url={http://dx.doi.org/10.1111/j.1432-1033.1995.tb20813.x}, DOI={10.1111/j.1432-1033.1995.tb20813.x}, number={1}, journal={European Journal of Biochemistry}, publisher={Wiley}, author={Blom, Jolanda and Dekker, Peter J. T. and Meijer, Michiel}, year={1995}, month=aug, pages={309–314} }

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