DOI: 10.1111/j.1432-1033.1985.tb09257.x. Phase equilibria in four lysophosphatidylcholine/water systems

Phase equilibria in four lysophosphatidylcholine/water systems

10.1111/j.1432-1033.1985.tb09257.x

Crossref journal-article

Wiley

European Journal of Biochemistry (311)

Abstract

The phase equilibria in four lysophosphatidylcholine/water systems were investigated at different temperatures. Each of the 1‐palmitoyl‐, 1‐stearoyl‐, 1‐oleoyl‐ and 1‐linoleoyl‐sn‐glycero‐3‐phosphocholines was dispersed in heavy water at different concentrations. The phase structures were determined by 2H‐, 14N‐ and 31P‐NMR, polarization microscopy and low‐angle X‐ray diffraction.The phase diagrams of the oleoyl and linoleoyl systems were quite similar. At room temperature and with decreasing water content the isotropic micellar solution was followed by a hexagonal phase and then a cubic phase. Finally the lamellar phase appeared before the region of hydrated crystals. The same sequence of phases was observed in the stearoyl system at elevated temperatures. The palmitoyl system differed from the others: here a cubic phase followed after the micellar solution, then came a hexagonal phase and after this a lamellar phase. In general the lysophosphatidylcholines seem to behave similarly to the many soaps and detergents as they show the same sequence of isotropic micellar solution, hexagonal phase, lamellar phase with interspersed cubic phases.The presently established phase diagrams demonstrate that the major lysophosphatidylcholines which may be generated by phospholipase A2 in mammalian cell membranes, viz. 1‐palmitoyl‐ and 1‐stearoyl‐glycerophosphocholines differ greatly in their packing properties. The extraordinary ability of 1‐palmitoyl‐glycerophosphocholine to form a cubic phase in equilibrium with a micellar solution is of particular interest with regard to the possible occurrence of cubic structures in biomembranes during the process of fusion.

Bibliography

ARVIDSON, G., BRENTEL, I., KHAN, A., LINDBLOM, G., & FONTELL, K. (1985). Phase equilibria in four lysophosphatidylcholine/water systems. European Journal of Biochemistry, 152(3), 753â759. Portico.

Authors 5

Gösta ARVIDSON (first)
Ingvar BRENTEL (additional)
Ali KHAN (additional)
Göran LINDBLOM (additional)
Krister FONTELL (additional)

References 31 Referenced 77

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{'key': 'e_1_2_3_23_2', 'first-page': '253', 'volume': '9', 'author': 'Wennerström H.', 'year': '1975', 'journal-title': 'Am. Chem. Soc. Symp. Ser.'} / Am. Chem. Soc. Symp. Ser. by Wennerström H. (1975)
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{'issue': '1', 'key': 'e_1_2_3_31_2', 'first-page': '9', 'volume': '1', 'author': 'Fontell K.', 'year': '1985', 'journal-title': 'Mol. Cryst. Liq. Cryst.'} / Mol. Cryst. Liq. Cryst. by Fontell K. (1985)
10.1016/0079-6832(78)90040-X

Dates

Type	When
Created	20 years, 5 months ago (March 3, 2005, 7:11 p.m.)
Deposited	1 year, 9 months ago (Nov. 22, 2023, 9:53 p.m.)
Indexed	4 months, 2 weeks ago (April 10, 2025, 10:43 a.m.)
Issued	39 years, 9 months ago (Nov. 1, 1985)
Published	39 years, 9 months ago (Nov. 1, 1985)
Published Online	20 years, 5 months ago (March 3, 2005)
Published Print	39 years, 9 months ago (Nov. 1, 1985)

Funders 0

None

BibTeX

@article{ARVIDSON_1985, title={Phase equilibria in four lysophosphatidylcholine/water systems: Exceptional behaviour of 1‐palmitoyl‐glycerophosphocholine}, volume={152}, ISSN={1432-1033}, url={http://dx.doi.org/10.1111/j.1432-1033.1985.tb09257.x}, DOI={10.1111/j.1432-1033.1985.tb09257.x}, number={3}, journal={European Journal of Biochemistry}, publisher={Wiley}, author={ARVIDSON, Gösta and BRENTEL, Ingvar and KHAN, Ali and LINDBLOM, Göran and FONTELL, Krister}, year={1985}, month=nov, pages={753–759} }

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