DOI: 10.1111/j.1432-1033.1982.tb06921.x. Luteinizing Hormone‐Releasing Hormone and Thyrotropin‐Releasing Hormone in Human and Bovine Milk

Luteinizing Hormone‐Releasing Hormone and Thyrotropin‐Releasing Hormone in Human and Bovine Milk

10.1111/j.1432-1033.1982.tb06921.x

Crossref journal-article

Wiley

European Journal of Biochemistry (311)

Abstract

Two hypothalamic peptide hormones, luteinizing hormone‐releasing hormone (LHRH) and thyrotropin‐releasing hormone (TRH), have been isolated from human milk and bovine colostrum. Acidified methanolic extracts, prepared from human milk, bovine colostrum and rat hypothalami, as well as synthetic LHRH and TRH markers were subjected to high‐pressure liquid chromatography (HPLC). The eluates were tested for the presence of LHRH and TRH by specific radioimmunoassays. It was found that milk extracts contain significant amounts of LHRH (3.9–11.8 ng/ml) and TRH (0.16–0.34 ng/ml), which comigrate with the corresponding marker hormones and with those of hypothalamic origin. The HPLC‐purified LHRH from both human and bovine milk was bioactive in a dose‐response manner similar to synthetic LHRH.

Bibliography

AMARANT, T., FRIDKIN, M., & KOCH, Y. (1982). Luteinizing HormoneâReleasing Hormone and ThyrotropinâReleasing Hormone in Human and Bovine Milk. European Journal of Biochemistry, 127(3), 647â650. Portico.

Authors 3

Tanchum AMARANT (first)
Mati FRIDKIN (additional)
Yitzhak KOCH (additional)

References 27 Referenced 55

10.1016/0024-3205(80)90610-4
10.1159/000393152
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{'key': 'e_1_2_2_5_2', 'first-page': '408', 'volume': '14', 'author': 'Sack J.', 'year': '1978', 'journal-title': 'Israel J. Med. Sci.'} / Israel J. Med. Sci. by Sack J. (1978)
10.1210/jcem-52-4-826
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Dates

Type	When
Created	15 years, 1 month ago (July 21, 2010, 12:55 p.m.)
Deposited	1 year, 9 months ago (Nov. 23, 2023, 2:30 a.m.)
Indexed	1 year, 2 months ago (June 12, 2024, 8:36 a.m.)
Issued	42 years, 11 months ago (Oct. 1, 1982)
Published	42 years, 11 months ago (Oct. 1, 1982)
Published Online	20 years, 6 months ago (March 3, 2005)
Published Print	42 years, 11 months ago (Oct. 1, 1982)

Funders 0

None

BibTeX

@article{AMARANT_1982, title={Luteinizing Hormone‐Releasing Hormone and Thyrotropin‐Releasing Hormone in Human and Bovine Milk}, volume={127}, ISSN={1432-1033}, url={http://dx.doi.org/10.1111/j.1432-1033.1982.tb06921.x}, DOI={10.1111/j.1432-1033.1982.tb06921.x}, number={3}, journal={European Journal of Biochemistry}, publisher={Wiley}, author={AMARANT, Tanchum and FRIDKIN, Mati and KOCH, Yitzhak}, year={1982}, month=oct, pages={647–650} }

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