DOI: 10.1111/j.1432-1033.1981.tb05577.x. Proteolytic Digestion Studies of Chromatin Core‐Histone Structure

Proteolytic Digestion Studies of Chromatin Core‐Histone Structure

10.1111/j.1432-1033.1981.tb05577.x

Crossref journal-article

Wiley

European Journal of Biochemistry (311)

Abstract

Trypsin digestion of chromatin results in a well‐defined set of limit peptides (P1‐P5) derived from the four core histones. Those from histones H3 and H4 have been identified. P1 is H3 residues 27‐129; P4 is H4 residues 18‐102 and P5 is H4 residues 20‐102.The N‐terminal sequences removed correlate well with the regions that undergo post‐synthetic acetylation and which show the greatest degree of sequence conservation. Autolytic digestion of chromatin releases a peptide (P1′) from H3 representing residues 21‐135. The implications of protease digestion of the higher order structure of chromatin are discussed.

Bibliography

BÃHM, L., BRIAND, G., SAUTIÃRE, P., & CRANEâROBINSON, C. (1981). Proteolytic Digestion Studies of Chromatin CoreâHistone Structure. European Journal of Biochemistry, 119(1), 67â74. Portico.

Authors 4

Lothar BÖHM (first)
Gilbert BRIAND (additional)
Pierre SAUTIÈRE (additional)
Colyn CRANE‐ROBINSON (additional)

References 35 Referenced 53

Dates

Type	When
Created	20 years, 5 months ago (March 3, 2005, 4:19 p.m.)
Deposited	1 year, 9 months ago (Nov. 22, 2023, 10:42 p.m.)
Indexed	1 year ago (Aug. 5, 2024, 2:39 a.m.)
Issued	43 years, 11 months ago (Sept. 1, 1981)
Published	43 years, 11 months ago (Sept. 1, 1981)
Published Online	20 years, 5 months ago (March 3, 2005)
Published Print	43 years, 11 months ago (Sept. 1, 1981)

Funders 0

None

BibTeX

@article{B_HM_1981, title={Proteolytic Digestion Studies of Chromatin Core‐Histone Structure: Identification of the Limit Peptides of Histones H3 and H4}, volume={119}, ISSN={1432-1033}, url={http://dx.doi.org/10.1111/j.1432-1033.1981.tb05577.x}, DOI={10.1111/j.1432-1033.1981.tb05577.x}, number={1}, journal={European Journal of Biochemistry}, publisher={Wiley}, author={BÖHM, Lothar and BRIAND, Gilbert and SAUTIÈRE, Pierre and CRANE‐ROBINSON, Colyn}, year={1981}, month=sep, pages={67–74} }

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