Abstract
Nascent intermediates in the synthesis of maltose‐binding protein, a periplasmic protein in Escherichia coli, were demonstrated both in vivo and in vitro. They are likely to result from a drastic reduction in the rate of elongation at specific sites on the mRNA leading to detectable accumulation of distinct species of incomplete polypeptides. In order to reach its final destination in the periplasmic space, maltose‐binding protein is transferred across the cytoplasmic membrane as it is elongated. It is possible that variations in the rate of elongation are involved in this export process.
References
10
Referenced
43
10.1016/0003-9861(78)90414-9
10.1016/S0021-9258(19)42459-9
/ J. Biol. Chem. by Protzel A. (1974)10.1073/pnas.76.12.6211
10.1111/j.1432-1033.1977.tb11502.x
10.1073/pnas.75.3.1209
10.1038/277538a0
10.1083/jcb.67.3.835
{'key': 'e_1_2_2_9_2', 'volume-title': 'Experiments in Molecular Genetics', 'author': 'Miller J. H.', 'year': '1972'}
/ Experiments in Molecular Genetics by Miller J. H. (1972)10.1111/j.1432-1033.1978.tb12761.x
10.1016/S0021-9258(19)75212-0
Dates
Type | When |
---|---|
Created | 15 years, 1 month ago (July 21, 2010, 1:26 p.m.) |
Deposited | 1 year, 9 months ago (Nov. 23, 2023, 2:25 a.m.) |
Indexed | 1 year, 7 months ago (Jan. 23, 2024, 6:29 p.m.) |
Issued | 45 years, 2 months ago (June 1, 1980) |
Published | 45 years, 2 months ago (June 1, 1980) |
Published Online | 20 years, 5 months ago (March 3, 2005) |
Published Print | 45 years, 2 months ago (June 1, 1980) |
@article{RANDALL_1980, title={Novel Intermediates in the Synthesis of Maltose‐Binding Protein in Escherichia coli}, volume={107}, ISSN={1432-1033}, url={http://dx.doi.org/10.1111/j.1432-1033.1980.tb06039.x}, DOI={10.1111/j.1432-1033.1980.tb06039.x}, number={2}, journal={European Journal of Biochemistry}, publisher={Wiley}, author={RANDALL, Linda L. and JOSEFSSON, Lars‐Göran and HARDY, Simon J. S.}, year={1980}, month=jun, pages={375–379} }