DOI: 10.1111/j.1423-0410.1986.tb00209.x. Red Cell Antigens P (Globoside) and Luke: Identification by Monoclonal Antibodies Defining the Murine Stage‐Specific Embryonic Antigens ‐3 and ‐4 (SSEA‐3 and SSEA‐4)<sup>1</sup>

Red Cell Antigens P (Globoside) and Luke: Identification by Monoclonal Antibodies Defining the Murine Stage‐Specific Embryonic Antigens ‐3 and ‐4 (SSEA‐3 and SSEA‐4)1

10.1111/j.1423-0410.1986.tb00209.x

Crossref journal-article

Wiley

Vox Sanguinis (311)

Abstract

Abstract. Two globoseries antigens (antigens borne on carbohydrate chains containing globoside), SSEA‐3 and SSEA‐4, were found on the red cells of the majority of people, but were absent from cells of rare p and Pk individuals which lack globoside. In addition, SSEA‐4 was absent from red cells of Luke(‐) individuals which nevertheless express the P antigen (globoside) and SSEA‐3. The name LKE is proposed for the red cell antigen detected by the Luke serum and by MC813–70, the monoclonal antibody defining SSEA‐4. Among the LKE+ individuals, a few showed relatively weak expression of the antigen and were grouped separately as a LKE weak (LKEw) phenotype. Using MC813–70, the frequencies of the 3 phenotypes LKE+, LKEw and LKE‐ in an English donor population are 0.914, 0.072 and 0.014, respectively.

Bibliography

Tippett, P., Andrews, P. W., Knowles, B. B., Solter, D., & Goodfellow, P. N. (1986). Red Cell Antigens P (Globoside) and Luke: Identification by Monoclonal Antibodies Defining the Murine StageâSpecific Embryonic Antigens â3 and â4 (SSEAâ3 and SSEAâ4)1. Vox Sanguinis, 51(1), 53â56. Portico.

Authors 5

Patricia Tippett (first)
Peter W. Andrews (additional)
Barbara B. Knowles (additional)
Davor Solter (additional)
Peter N. Goodfellow (additional)

References 14 Referenced 51

10.1016/0092-8674(82)90274-4
10.1002/j.1460-2075.1983.tb01746.x
{'key': 'e_1_2_1_4_2', 'first-page': '523', 'article-title': 'Cell surface antigens of a clonal human embryonal carcinoma cell line: morphological and antigenic differentiation in culture. Int. J', 'volume': '29', 'author': 'Andrews P.W.', 'year': '1982', 'journal-title': 'Cancer'} / Cancer / Cell surface antigens of a clonal human embryonal carcinoma cell line: morphological and antigenic differentiation in culture. Int. J by Andrews P.W. (1982)
{'key': 'e_1_2_1_5_2', 'first-page': '41', 'article-title': 'Human teratocarcinoma cells in culture', 'volume': '2', 'author': 'Andrews P.W.', 'year': '1983', 'journal-title': 'Cancer Surveys'} / Cancer Surveys / Human teratocarcinoma cells in culture by Andrews P.W. (1983)
{'key': 'e_1_2_1_6_2', 'first-page': '147', 'article-title': 'Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera‐2: differentiation in vivo and in vitro', 'volume': '50', 'author': 'Andrews P.W.', 'year': '1984', 'journal-title': 'Lab. Invest.'} / Lab. Invest. / Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera‐2: differentiation in vivo and in vitro by Andrews P.W. (1984)
{'key': 'e_1_2_1_7_2', 'first-page': '225', 'article-title': 'Immunohistochemical localization of murine stagespecific embryonic antigens in human testicular germ cell tumors', 'volume': '108', 'author': 'Damjanov I.', 'year': '1982', 'journal-title': 'Am. J. Path.'} / Am. J. Path. / Immunohistochemical localization of murine stagespecific embryonic antigens in human testicular germ cell tumors by Damjanov I. (1982)
{'key': 'e_1_2_1_8_2', 'first-page': '8934', 'article-title': 'New globoseries glycosphingolipids in human teratocarcinoma reactive with the monoclonal antibody directed to a developmentally regulated antigen stage‐specific antigen 3. J. biol.', 'volume': '258', 'author': 'Kannagi R.', 'year': '1982', 'journal-title': 'Chem.'} / Chem. / New globoseries glycosphingolipids in human teratocarcinoma reactive with the monoclonal antibody directed to a developmentally regulated antigen stage‐specific antigen 3. J. biol. by Kannagi R. (1982)
10.1016/0006-291X(74)90426-4
10.1111/j.1423-0410.1965.tb01390.x
{'key': 'e_1_2_1_11_2', 'volume-title': 'Blood groups in man', 'author': 'Race R.R.', 'year': '1975'} / Blood groups in man by Race R.R. (1975)
10.1046/j.1537-2995.1977.17678075653.x
Soderstrom T.;Enskogh A.;Samuelsson B.E.;Cedergren B.:IgG3‐restriction of anti‐P and anti‐Pkantibodies may explain the early abortions in mothers of the p blood group.Abstr. 18th Congr. Int. Soc. Blood Transf. Munich1984 p.226.
10.1016/0090-1229(83)90163-0
10.1016/0012-1606(84)90028-9

Dates

Type	When
Created	16 years, 5 months ago (March 5, 2009, 5:47 p.m.)
Deposited	1 year, 10 months ago (Oct. 20, 2023, 9:17 p.m.)
Indexed	1 year ago (Aug. 8, 2024, 10:36 a.m.)
Issued	39 years, 2 months ago (July 1, 1986)
Published	39 years, 2 months ago (July 1, 1986)
Published Online	16 years, 5 months ago (March 5, 2009)
Published Print	39 years, 2 months ago (July 1, 1986)

Funders 0

None

BibTeX

@article{Tippett_1986, title={Red Cell Antigens P (Globoside) and Luke: Identification by Monoclonal Antibodies Defining the Murine Stage‐Specific Embryonic Antigens ‐3 and ‐4 (SSEA‐3 and SSEA‐4)1}, volume={51}, ISSN={1423-0410}, url={http://dx.doi.org/10.1111/j.1423-0410.1986.tb00209.x}, DOI={10.1111/j.1423-0410.1986.tb00209.x}, number={1}, journal={Vox Sanguinis}, publisher={Wiley}, author={Tippett, Patricia and Andrews, Peter W. and Knowles, Barbara B. and Solter, Davor and Goodfellow, Peter N.}, year={1986}, month=jul, pages={53–56} }

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