DOI: 10.1111/j.1423-0410.1971.tb00578.x. Observations of the Number of Available c, D, and E Antigen Sites on Red Cells

Observations of the Number of Available c, D, and E Antigen Sites on Red Cells

10.1111/j.1423-0410.1971.tb00578.x

Crossref journal-article

Wiley

Vox Sanguinis (311)

Abstract

Abstract. The number of available antigen sites within the Rh system were estimated using trace‐labelled antibodies. The results were as follows, given as the number of sites per red cell: c‐antigen: on cc cells, 70,000–85,000: on Cc, 37,000–53,000; D sites on cells of phenotype ‐D‐: 110,000–202,000; E‐antigen sites showed considerable heterogeneity depending on phenotype as well as source of anti‐E, and estimates varied between 450 and 25,600; e‐antigen: on eE cells, 13,400 and 14,500: on ee cells, 18,200 and 24,400.The average equilibrium constants of the antibodies were: anti‐E, 4 × 108 1/mol; anti‐e, 2.5 × 108 1/mol; anti‐c, 3.2 × 107 and 5.6 × 107 1/mol.

Bibliography

HUGHESâJONES, N. C., GARDNER, B., & LINCOLN, P. J. (1971). Observations of the Number of Available c, D, and E Antigen Sites on Red Cells. Vox Sanguinis, 21(3), 210â216. Portico.

Authors 3

N. C. HUGHES‐JONES (first)
BRIGITTE GARDNER (additional)
P. J. LINCOLN (additional)

References 10 Referenced 65

{'key': 'e_1_2_1_2_2', 'first-page': '565', 'article-title': 'The estimation of the concentration and equilibrium constant of anti‐D', 'volume': '12', 'author': 'Hughes‐Jones N. C.', 'year': '1967', 'journal-title': 'Immunology'} / Immunology / The estimation of the concentration and equilibrium constant of anti‐D by Hughes‐Jones N. C. (1967)
10.1042/bj0850466
10.1111/j.1423-0410.1963.tb04180.x
10.1084/jem.42.6.853
10.1038/182053a0
10.1038/163913a0
10.1111/j.1423-0410.1965.tb05179.x
10.1136/jcp.16.1.70
10.1182/blood.V17.3.291.291 / Blood / Quantitive haemagglutination studies in the Rh blood group system. II. A study of the D (Rh0) agglutinogen by Silber R. (1961)
10.1111/j.1365-2141.1957.tb05797.x

Dates

Type	When
Created	16 years, 5 months ago (March 5, 2009, 9:36 p.m.)
Deposited	1 year, 9 months ago (Nov. 10, 2023, 6:11 p.m.)
Indexed	1 month, 3 weeks ago (June 27, 2025, 5:42 p.m.)
Issued	53 years, 11 months ago (Sept. 1, 1971)
Published	53 years, 11 months ago (Sept. 1, 1971)
Published Online	16 years, 5 months ago (March 5, 2009)
Published Print	53 years, 11 months ago (Sept. 1, 1971)

Funders 0

None

BibTeX

@article{HUGHES_JONES_1971, title={Observations of the Number of Available c, D, and E Antigen Sites on Red Cells}, volume={21}, ISSN={1423-0410}, url={http://dx.doi.org/10.1111/j.1423-0410.1971.tb00578.x}, DOI={10.1111/j.1423-0410.1971.tb00578.x}, number={3}, journal={Vox Sanguinis}, publisher={Wiley}, author={HUGHES‐JONES, N. C. and GARDNER, BRIGITTE and LINCOLN, P. J.}, year={1971}, month=sep, pages={210–216} }

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