DOI: 10.1111/j.1399-302x.1993.tb00567.x. Viscosity‐dependent locomotion of oral spirochetes

Viscosity‐dependent locomotion of oral spirochetes

10.1111/j.1399-302x.1993.tb00567.x

Crossref journal-article

Wiley

Oral Microbiology and Immunology (311)

Abstract

Spirochetes are thought to remain motile in environments (such as intercellular spaces) that immobilize extracellularly flagellated eubacteria. This attribute suggests that the viscosity of the milieu is of importance to locomotion. We sought to determine the interdependence of oral spirochete locomotion with media viscosity. Video time‐lapse microscopy using darkfield optics was used. The motility of the spirochetes in media of different viscosities (various concentrations of Noble agar was measured. Treponema denticola exhibited the fastest speed (18.7 ± 4.4 μ/min) at a viscosity of 30 mPa s. The highest speeds for Treponema vincentii and Treponema socranskii were 41.9 ± 14.9 and 33.4 ± 13.2 μm/min, respectively, at 88 mPa s. These data show that optimal migration of spirochetes is viscosity‐dependent. The results support the hypothesis that such viscosity‐dependent locomotion could be a virulence factor that enables oral spirochetes to initiate and sustain periodontal disease.

Bibliography

Klitorinos, A., Noble, P., Siboo, R., & Chan, E. C. S. (1993). Viscosityâdependent locomotion of oral spirochetes. Oral Microbiology and Immunology, 8(4), 242â244. Portico.

Authors 4

A. Klitorinos (first)
P. Noble (additional)
R. Siboo (additional)
E. C. S. Chan (additional)

References 10 Referenced 33

10.1038/255656a0
10.1093/infdis/162.5.1205
10.1902/jop.1984.55.10.567
10.1177/00220345840630110601
10.1139/m88-127
10.1097/00007435-198101000-00001
10.1128/iai.59.10.3377-3380.1991 / Infect Immun / Pathogen‐related oral spirochetes from dental plaque are invasive by Riviere GR (1991)
10.1093/clinids/11.Supplement_6.S1460
10.1128/JB.117.2.696-701.1974
10.1128/iai.56.4.726-728.1988 / Infect Immun / Quantitative relationship of T. microdentium to severity of periodontal disease by Simonson LG (1988)

Dates

Type	When
Created	17 years, 8 months ago (Dec. 19, 2007, 3:12 a.m.)
Deposited	1 year, 10 months ago (Oct. 25, 2023, 3:04 p.m.)
Indexed	1 year, 1 month ago (Aug. 3, 2024, 2:35 a.m.)
Issued	32 years, 1 month ago (Aug. 1, 1993)
Published	32 years, 1 month ago (Aug. 1, 1993)
Published Online	17 years, 8 months ago (Dec. 19, 2007)
Published Print	32 years, 1 month ago (Aug. 1, 1993)

Funders 0

None

BibTeX

@article{Klitorinos_1993, title={Viscosity‐dependent locomotion of oral spirochetes}, volume={8}, ISSN={1399-302X}, url={http://dx.doi.org/10.1111/j.1399-302x.1993.tb00567.x}, DOI={10.1111/j.1399-302x.1993.tb00567.x}, number={4}, journal={Oral Microbiology and Immunology}, publisher={Wiley}, author={Klitorinos, A. and Noble, P. and Siboo, R. and Chan, E. C. S.}, year={1993}, month=aug, pages={242–244} }

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