DOI: 10.1111/j.1399-0004.1981.tb00660.x. Family analysis of Werner's syndrome: A survey of 42 Japanese families with a review of the literature

Family analysis of Werner's syndrome: A survey of 42 Japanese families with a review of the literature

10.1111/j.1399-0004.1981.tb00660.x

Crossref journal-article

Wiley

Clinical Genetics (311)

Abstract

Forty‐two Japanese families, including 80 individuals with Werner's syndrome were studied, confirming that this syndrome is inherited as an autosomal recessive trait. The incidence of malignancy was relatively high in these families and individuals with Werner's syndrome, although the incidence was not so high as was reported previously. HLA typing revealed no significant linkage with Werner's syndrome. The frequency of Werner's syndrome in Japan was estimated using two methods which indicated approximately 300 cases among 100 million people.

Bibliography

Goto, M., Tanimoto, K., Horiuchi, Y., & Sasazuki, T. (1981). Family analysis of Wernerâs syndrome: A survey of 42 Japanese families with a review of the literature. Clinical Genetics, 19(1), 8â15. Portico.

Authors 4

Makoto Goto (first)
Kiyoaki Tanimoto (additional)
Yoshihiko Horiuchi (additional)
Takehiko Sasazuki (additional)

References 16 Referenced 111

{'key': 'e_1_2_1_2_1', 'first-page': '492', 'article-title': 'Precocious cataracts and scleroderma', 'volume': '21', 'author': 'Agatson S. A.', 'year': '1939', 'journal-title': 'Arch. Ophthal.'} / Arch. Ophthal. / Precocious cataracts and scleroderma by Agatson S. A. (1939)
10.2340/0001555556149150 / Acta dermatol. (Stockh.) / Werner's syndrome and malignancy by Björnberg A. (1976)
{'key': 'e_1_2_1_4_1', 'first-page': '90', 'article-title': 'Methods for population genetics', 'volume': '25', 'author': 'Dahlberg G.', 'year': '1950', 'journal-title': 'Amer. J. Biol.'} / Amer. J. Biol. / Methods for population genetics by Dahlberg G. (1950)
{'key': 'e_1_2_1_5_1', 'first-page': '197', 'article-title': "Werner's syndrome: A review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process", 'volume': '45', 'author': 'Epstein C. J.', 'year': '1966', 'journal-title': 'Medicine (Baltimore)'} / Medicine (Baltimore) / Werner's syndrome: A review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process by Epstein C. J. (1966)
10.1093/jnci/52.6.1909 / J. nat. Cancer Inst. / HLA‐A heterozygosity as a genetic marker of long‐term survival by Gerkins V. R. (1974)
10.1111/j.1532-5415.1978.tb03681.x
10.1016/0009-8981(78)90227-9
10.1172/JCI109511
{'key': 'e_1_2_1_10_1', 'first-page': '1', 'article-title': 'Genetic tests under incomplete ascertainment', 'volume': '11', 'author': 'Morton N. E.', 'year': '1959', 'journal-title': 'Amer. J. hum. Genet.'} / Amer. J. hum. Genet. / Genetic tests under incomplete ascertainment by Morton N. E. (1959)
{'key': 'e_1_2_1_11_1', 'first-page': '156', 'article-title': 'The incidence of consanguineous matings in Japan. With remarks on the estimation of comparative gene frequencies and the expected rate of induced recessive mutations', 'volume': '1', 'author': 'Neel J. V.', 'year': '1949', 'journal-title': 'Amer. J. hum. Genet.'} / Amer. J. hum. Genet. / The incidence of consanguineous matings in Japan. With remarks on the estimation of comparative gene frequencies and the expected rate of induced recessive mutations by Neel J. V. (1949)
10.1097/00000441-194111000-00002
10.1016/0002-9394(63)92334-1
10.1259/0007-1285-43-507-193
10.1111/j.1399-0039.1976.tb01037.x
{'key': 'e_1_2_1_16_1', 'first-page': '18', 'volume-title': 'Cancer Mortality for Selected Sites in 24 Countries', 'author': 'Segi M.', 'year': '1972'} / Cancer Mortality for Selected Sites in 24 Countries by Segi M. (1972)
{'key': 'e_1_2_1_17_1', 'first-page': '123', 'article-title': "Werner's syndrome: An analysis of ten cases", 'volume': '23', 'author': 'Zucker‐Franklin D.', 'year': '1968', 'journal-title': 'Geriatrics'} / Geriatrics / Werner's syndrome: An analysis of ten cases by Zucker‐Franklin D. (1968)

Dates

Type	When
Created	15 years, 1 month ago (July 18, 2010, 8:53 p.m.)
Deposited	1 year, 9 months ago (Nov. 10, 2023, 10:49 a.m.)
Indexed	2 days, 2 hours ago (Sept. 4, 2025, 9:40 a.m.)
Issued	44 years, 8 months ago (Jan. 1, 1981)
Published	44 years, 8 months ago (Jan. 1, 1981)
Published Online	17 years, 4 months ago (April 23, 2008)
Published Print	44 years, 8 months ago (Jan. 1, 1981)

Funders 0

None

BibTeX

@article{Goto_1981, title={Family analysis of Werner’s syndrome: A survey of 42 Japanese families with a review of the literature}, volume={19}, ISSN={1399-0004}, url={http://dx.doi.org/10.1111/j.1399-0004.1981.tb00660.x}, DOI={10.1111/j.1399-0004.1981.tb00660.x}, number={1}, journal={Clinical Genetics}, publisher={Wiley}, author={Goto, Makoto and Tanimoto, Kiyoaki and Horiuchi, Yoshihiko and Sasazuki, Takehiko}, year={1981}, month=jan, pages={8–15} }

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