DOI: 10.1111/j.1365-2958.1994.tb01285.x. Growth and viability of <i>Streptomyces coelicolor</i> mutant for the cell division gene <i>ftsZ</i>

Growth and viability of Streptomyces coelicolor mutant for the cell division gene ftsZ

10.1111/j.1365-2958.1994.tb01285.x

Crossref journal-article

Wiley

Molecular Microbiology (311)

Abstract

SummaryA homologue of the bacterial cell division gene ftsZ was cloned from the filamentous bacterium Streptomyces coelicolor. The gene was located on the physical map of the chromosome at about ‘11 o'clock’ (in the vicinity of glkA, hisA and trpB). Surprisingly, a null mutant in which the 399‐codon ftsZ open reading frame was largely deleted was viable, even though the mutant was blocked in septum formation. This indicates that cell division may not be essential for the growth and viability of S. coelicolor. The ftsZ mutant was able to produce aerial hyphae but was unable to produce spores, a finding consistent with the idea that ftsZ is required in order for aerial hyphae to undergo septation into the uninucleoid cells that differentiate into spores.

Bibliography

McCormick, J. R., Su, E. P., Driks, A., & Losick, R. (1994). Growth and viability of Streptomyces coelicolor mutant for the cell division gene ftsZ. Molecular Microbiology, 14(2), 243â254. Portico.

Authors 4

Joseph R. McCormick (first)
Edwin P. Su (additional)
Adam Driks (additional)
Richard Losick (additional)

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Dates

Type	When
Created	18 years, 9 months ago (Oct. 27, 2006, 10:44 p.m.)
Deposited	1 year, 11 months ago (Sept. 5, 2023, 2:53 a.m.)
Indexed	21 hours, 41 minutes ago (Aug. 24, 2025, 7:06 p.m.)
Issued	30 years, 10 months ago (Oct. 1, 1994)
Published	30 years, 10 months ago (Oct. 1, 1994)
Published Online	18 years, 9 months ago (Oct. 27, 2006)
Published Print	30 years, 10 months ago (Oct. 1, 1994)

Funders 0

None

BibTeX

@article{McCormick_1994, title={Growth and viability of Streptomyces coelicolor mutant for the cell division gene ftsZ}, volume={14}, ISSN={1365-2958}, url={http://dx.doi.org/10.1111/j.1365-2958.1994.tb01285.x}, DOI={10.1111/j.1365-2958.1994.tb01285.x}, number={2}, journal={Molecular Microbiology}, publisher={Wiley}, author={McCormick, Joseph R. and Su, Edwin P. and Driks, Adam and Losick, Richard}, year={1994}, month=oct, pages={243–254} }

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