Abstract
SUMMARY. The main method of classification of chronic viral hepatitis is now by cause, and the old histology‐based classification is no longer considered appropriate. However, liver biopsy remains an important part of patient assessment and, in the context of clinical trials, biopsy findings are often scored in a semiquantitative manner. The concepts of grading and staging, borrowed from tumour pathology, have been introduced, representing the severity of the necroinflammatory lesion and the extent of its structural consequences respectively. The pathology of the individual forms of viral hepatitis A to G shows more similarities than differences. However, some pathological features are commonly associated with specific viruses. The combination of portal lymphoid follicles, bile duct damage, lobular activity and steatosis give chronic hepatitis C a characteristic histological profile. Very similar appearances have been noted in the limited number of biopsies so far reported from patients with known combined hepatitis C and G virus infection.
References
51
Referenced
39
{'key': 'e_1_2_2_2_2', 'volume-title': 'Diseases of the Liver and Billary Tract. Standardization of Nomenclature, Diagnostic Criteria, and Diagnostic Methodology.', 'author': 'Leevy CM', 'year': '1976'}
/ Diseases of the Liver and Billary Tract. Standardization of Nomenclature, Diagnostic Criteria, and Diagnostic Methodology. by Leevy CM (1976){'key': 'e_1_2_2_3_2', 'volume-title': 'Diseases of the Liver and Biliary Tract. Standardization of Nomenclature, Diagnostic Criteria, and Prognosis.', 'author': 'International Hepatology Informatics Group.', 'year': '1994'}
/ Diseases of the Liver and Biliary Tract. Standardization of Nomenclature, Diagnostic Criteria, and Prognosis. by International Hepatology Informatics Group. (1994)10.1111/j.1600-0676.1982.tb00178.x
10.1016/S0140-6736(68)90710-1
10.1016/0168-8278(91)90084-O
10.1016/0016-5085(93)90037-D
10.1002/hep.1840060302
10.1002/hep.1840060332
10.1056/NEJM197011122832001
10.1002/hep.1840190629
{'key': 'e_1_2_2_12_2', 'first-page': 'S177', 'article-title': 'Terminology of chronic hepatitis, hepatic allograft rejection, and nodular lesions of the liver: summary of recommendations developed by an international working party, supported by the World Congresses of Gastroenterology, Los Angeles, 1994', 'volume': '89', 'author': 'International Working Party.', 'year': '1994', 'journal-title': 'Am J Gastroenterol'}
/ Am J Gastroenterol / Terminology of chronic hepatitis, hepatic allograft rejection, and nodular lesions of the liver: summary of recommendations developed by an international working party, supported by the World Congresses of Gastroenterology, Los Angeles, 1994 by International Working Party. (1994)10.1136/gut.37.2.274
10.1002/hep.1840010511
10.1136/jcp.38.5.530
10.1002/hep.1840200104
10.1002/hep.1840150402
10.1002/hep.1840150403
10.1016/0016-5085(93)90432-C
10.1111/j.1365-2559.1995.tb00191.x
10.1016/0168-8278(95)80226-6
10.1016/S0140-6736(96)90286-X
{'key': 'e_1_2_2_23_2', 'article-title': 'Reporting chronic viral hepatitis: intraobserver variation when using the Knodell and Scheuer systems', 'volume': '170', 'author': 'Patel N', 'year': '1993', 'journal-title': 'J Pathol'}
/ J Pathol / Reporting chronic viral hepatitis: intraobserver variation when using the Knodell and Scheuer systems by Patel N (1993)10.1016/S0168-8278(86)80023-X
10.1007/BF00713431
10.1128/jvi.68.12.7810-7815.1994
/ J Virol / Isolation of the novel agent from human stool samples that is associated with sporadic non‐A, non‐B hepatitis by Deka N (1994)10.1111/j.1600-0676.1994.tb00084.x
{'key': 'e_1_2_2_28_2', 'first-page': '349', 'volume-title': 'Pathology of the Liver.', 'author': 'Bianchi L', 'year': '1994'}
/ Pathology of the Liver. by Bianchi L (1994)10.1002/hep.1840220405
10.1136/jcp.48.5.470
10.1016/0016-5085(95)90760-2
{'key': 'e_1_2_2_32_2', 'first-page': '7', 'article-title': 'Hepatitis B e antigen negative chronic hepatitis B: from clinical recognition to pathogencsis and treatment', 'volume': '1', 'author': 'Hadziyannis SJ', 'year': '1995', 'journal-title': 'Vir Hep Rev'}
/ Vir Hep Rev / Hepatitis B e antigen negative chronic hepatitis B: from clinical recognition to pathogencsis and treatment by Hadziyannis SJ (1995)10.1002/hep.1840220605
10.1002/hep.1840210102
10.1002/hep.1840130122
10.1136/gut.34.1.1
10.1056/NEJM199504203321604
10.1016/0270-9139(95)94776-0
{'key': 'e_1_2_2_39_2', 'first-page': '937', 'article-title': 'Hepatitic bile duct injuries in chronic hepatitis C: histopathologic and immunohistochemical studies', 'volume': '7', 'author': 'Kaji K', 'year': '1994', 'journal-title': 'Modern Pathol'}
/ Modern Pathol / Hepatitic bile duct injuries in chronic hepatitis C: histopathologic and immunohistochemical studies by Kaji K (1994)10.1016/0046-8177(93)90189-N
10.1046/j.1365-2559.1996.d01-418.x
10.1002/path.1711750112
10.1002/hep.1840190202
10.1016/S0168-8278(05)80119-9
10.1111/j.1600-0676.1993.tb00631.x
10.1002/(SICI)1096-9071(199603)48:3<227::AID-JMV3>3.0.CO;2-A
10.1111/j.1600-0676.1996.tb00704.x
10.1016/0168-8278(95)80256-8
10.1002/hep.510230202
10.1056/NEJM199102143240705
10.1126/science.271.5248.505
10.1016/S0140-6736(96)91267-2
Dates
Type | When |
---|---|
Created | 17 years, 8 months ago (Dec. 19, 2007, 2:54 a.m.) |
Deposited | 1 year, 10 months ago (Oct. 26, 2023, 11:42 a.m.) |
Indexed | 1 month ago (July 30, 2025, 10:41 a.m.) |
Issued | 28 years, 10 months ago (Nov. 1, 1996) |
Published | 28 years, 10 months ago (Nov. 1, 1996) |
Published Online | 17 years, 8 months ago (Dec. 18, 2007) |
Published Print | 28 years, 10 months ago (Nov. 1, 1996) |
@article{Scheuer_1996, title={Histopathological aspects of viral hepatitis}, volume={3}, ISSN={1365-2893}, url={http://dx.doi.org/10.1111/j.1365-2893.1996.tb00099.x}, DOI={10.1111/j.1365-2893.1996.tb00099.x}, number={6}, journal={Journal of Viral Hepatitis}, publisher={Wiley}, author={Scheuer, P. J. and Davies, S. E. and Dhillon, A. P.}, year={1996}, month=nov, pages={277–283} }