Abstract
Heating properties of magnetite cationic liposomes (MCL) were investigated in ex vivo experiments using implanted cell pellets. The cell pellets, which consisted of rat glioma T9 cells into which MCL had been incorporated in a petri dish, were implanted subcntaneously in the left femoral region of female F344 rats. The rats were placed in a magnetic field generating coil and irradiated with an alternating magnetic field (384 Oe, 118 kHz) for 60 min. The cell pellets were heated to over 43°C by MCL in the magnetic field, hut other body parts of the rats were not heated. After 3 cycles of magnetic heating, all glioma cells were killed and no tumor take was observed.
References
5
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Dates
Type | When |
---|---|
Created | 20 years ago (Aug. 23, 2005, 11:12 p.m.) |
Deposited | 1 year, 10 months ago (Oct. 26, 2023, 9:11 p.m.) |
Indexed | 1 month, 3 weeks ago (July 14, 2025, 11:20 p.m.) |
Issued | 28 years, 2 months ago (July 1, 1997) |
Published | 28 years, 2 months ago (July 1, 1997) |
Published Online | 20 years ago (Aug. 24, 2005) |
Published Print | 28 years, 2 months ago (July 1, 1997) |
@article{Yanase_1997, title={Intracellular Hyperthermia for Cancer Using Magnetite Cationic Liposomes: Ex vivo Study}, volume={88}, ISSN={0910-5050}, url={http://dx.doi.org/10.1111/j.1349-7006.1997.tb00429.x}, DOI={10.1111/j.1349-7006.1997.tb00429.x}, number={7}, journal={Japanese Journal of Cancer Research}, publisher={Wiley}, author={Yanase, Mitsugu and Shinkai, Masashige and Honda, Hiroyuki and Wakabayashi, Toshihiko and Yoshida, Jun and Kobayashi, Takeshi}, year={1997}, month=jul, pages={630–632} }