DOI: 10.1111/j.1348-0421.1994.tb01836.x. Binding of Host‐Associated Treponeme Proteins to Collagens and Laminin: A Possible Mechanism of Spirochetal Adherence to Host Tissues

Binding of Host‐Associated Treponeme Proteins to Collagens and Laminin: A Possible Mechanism of Spirochetal Adherence to Host Tissues

10.1111/j.1348-0421.1994.tb01836.x

Crossref journal-article

Wiley

Microbiology and Immunology (311)

Abstract

AbstractThe polypeptides of seven strains of human treponemes were investigated by immunoblot analysis for their binding to the human placental collagens and laminin. Of the treponemal polypeptides, eleven polypeptides, 45‐kDa, 49‐kDa, and 62‐kDa polypeptides from T. pallidum ATCC 27087, a 48‐kDa polypeptide from T. phagedenis biotype Reiter, 51‐kDa and 53‐kDa polypeptides from T. vincentii ATCC 35580, 30‐kDa, 53‐kDa and 63‐kDa polypeptides from T. socranskii subsp. buccale ATCC 35534, a 52‐kDa polypeptide from T. denticola ATCC 35405, and a 53‐kDa polypeptide from T. denticola ATCC 33520 possessed an ability to bind to the laminin, type I, III, IV, or V collagen. An intermediate‐sized human oral isolate strain G7201 did not possess any laminin‐ or collagen‐binding polypeptides. Immunoelectron microscopy using intact treponemal cells with a single collagen‐binding polypeptide and the corresponding antisera demonstrated that the 51‐kDa and 53‐kDa polypeptides from T. vincentii, the 53‐kDa polypeptide from T. socranskii subsp. buccale ATCC 35534 and the 52‐kDa polypeptide from T. denticola ATCC 35405, were outer envelope proteins.

Bibliography

Umemoto, T., & Namikawa, I. (1994). Binding of HostâAssociated Treponeme Proteins to Collagens and Laminin: A Possible Mechanism of Spirochetal Adherence to Host Tissues. Microbiology and Immunology, 38(8), 655â663. Portico.

Authors 2

Toshihiko Umemoto (first)
Isamu Namikawa (additional)

References 39 Referenced 28

{'key': 'e_1_2_2_2_1', 'first-page': '39', 'article-title': 'Proteins of the periodontium. Characterization of the insoluble collagens of bovine dental cementum', 'volume': '23', 'author': 'Birkedal H.', 'year': '1977', 'journal-title': 'Calc. Tiss. Res.'} / Calc. Tiss. Res. / Proteins of the periodontium. Characterization of the insoluble collagens of bovine dental cementum by Birkedal H. (1977)
10.1128/jb.171.12.6674-6679.1989
10.1146/annurev.mi.35.100181.000333
{'key': 'e_1_2_2_5_1', 'first-page': '357', 'article-title': 'Attachment of Treponema pallidum to fibronectin, laminin, collagen IV, and collagen I, and blockage of attachment by immune rabbit IgG', 'volume': '60', 'author': 'Fitzgerald T.A.', 'year': '1984', 'journal-title': 'Br. J. Vener. Dis.'} / Br. J. Vener. Dis. / Attachment of Treponema pallidum to fibronectin, laminin, collagen IV, and collagen I, and blockage of attachment by immune rabbit IgG by Fitzgerald T.A. (1984)
10.1128/iai.59.11.4230-4237.1991 / Infect. Immun. / Sulfhydryl dependent attachment of Treponema denticola to laminin and other proteins by Haapasalo M. (1991)
10.1128/iai.54.2.359-364.1986 / Infect. Immun. / Collagen binding of Staphylococcus aureus by Holderbaun D. (1986)
10.1016/0003-9969(92)90130-Z
10.1111/j.1399-302X.1993.tb00567.x
10.1093/clinids/14.1.340
10.1111/j.1600-0765.1994.tb01093.x
10.1038/255656a0
10.1177/00220345810600021201
10.1111/j.1365-2958.1993.tb01114.x
10.1038/227680a0
10.1073/pnas.68.2.454
10.1111/j.1399-302X.1991.tb00443.x
10.1016/S0021-9258(19)52451-6
10.1128/iai.61.6.2479-2485.1993 / Infect. Immun. / Identification of a Staphylococcus auresus extracellular matrix‐binding protein with broad specificity by McGavin M.H. (1993)
10.1177/00220345880670080301
10.1111/j.1399-302X.1993.tb00576.x
10.2330/joralbiosci1965.36.330
10.1016/S0021-9258(17)33082-X / J. Biol. Chem. / Biochemical characterization of collagens synthesized by fibroblasts derived from normal and diseased human gingiva by Narayanan A.S. (1976)
10.1021/bi00563a016
10.1097/00007435-198101000-00001
Ruby J.D. Curci J. Goldstein S. andCharon N.W.1991.Evidence that the periplasmic flagella ofTreponema denticolaandTeponema phagedeniscan be external.1–86 p.204 Abstr. 91st Gen. Meet. Am. Soc. Microbiol.
{'key': 'e_1_2_2_27_1', 'first-page': '16536', 'article-title': 'Laminin, a multidomain protein', 'volume': '263', 'author': 'Sasaki M.', 'year': '1988', 'journal-title': 'J. Biol. Chem.'} / J. Biol. Chem. / Laminin, a multidomain protein by Sasaki M. (1988)
10.1099/00207713-34-4-457
10.1128/jb.167.1.77-81.1986
10.1128/iai.57.11.3314-3323.1989 / Infect. Immun. / Molecular characterization of the pathogen‐specific, 34‐kilodalton membrane immunogen of Treponema pallidum by Swancutt M.A. (1989)
10.1016/S0021-9258(19)30048-1 / J. Biol. Chem. / Isolation and characterization of a putative collagen receptor from Staphylococcus aureus strain Cowan 1 by Switalski L.M. (1989)
10.1073/pnas.76.9.4350
10.1128/iai.57.1.213-218.1989 / Infect. Immun. / A protease of Bacteroides gingivalis degrades cell surface and matrix glycoproteins of cultured gingival fibroblasts, and induced secretion of collagenase and plasminogen activator by Uitto V.‐J. (1989)
10.1128/iai.57.8.2470-2474.1989 / Infect. Immun. / A major antigen on the outer envelope of a human oral spirochete, Treponema denticola by Umemoto T. (1989)
10.1111/j.1348-0421.1993.tb03182.x
10.1128/jb.173.21.6935-6947.1991
10.1902/jop.1988.59.1.40
10.1016/S0021-9258(17)30083-2 / J. Biol. Chem. / The complete primary structure of a proline‐rich phosphoprotein from human saliva by Wong R.S. (1979)
10.1111/j.1399-302X.1991.tb00488.x
10.1111/j.1600-051X.1985.tb01348.x

Dates

Type	When
Created	11 years, 9 months ago (Nov. 14, 2013, 12:27 p.m.)
Deposited	1 year, 9 months ago (Nov. 20, 2023, 1:09 p.m.)
Indexed	1 year, 3 months ago (June 1, 2024, 2:27 a.m.)
Issued	31 years, 1 month ago (Aug. 1, 1994)
Published	31 years, 1 month ago (Aug. 1, 1994)
Published Online	11 years, 9 months ago (Nov. 14, 2013)
Published Print	31 years, 1 month ago (Aug. 1, 1994)

Funders 0

None

BibTeX

@article{Umemoto_1994, title={Binding of Host‐Associated Treponeme Proteins to Collagens and Laminin: A Possible Mechanism of Spirochetal Adherence to Host Tissues}, volume={38}, ISSN={1348-0421}, url={http://dx.doi.org/10.1111/j.1348-0421.1994.tb01836.x}, DOI={10.1111/j.1348-0421.1994.tb01836.x}, number={8}, journal={Microbiology and Immunology}, publisher={Wiley}, author={Umemoto, Toshihiko and Namikawa, Isamu}, year={1994}, month=aug, pages={655–663} }

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