DOI: 10.1111/j.1151-2916.2003.tb03375.x. Investigation of Apatite Deposition onto Charged Surfaces in Aqueous Solutions Using a Quartz‐Crystal Microbalance

Investigation of Apatite Deposition onto Charged Surfaces in Aqueous Solutions Using a Quartz‐Crystal Microbalance

10.1111/j.1151-2916.2003.tb03375.x

Crossref journal-article

Wiley

Journal of the American Ceramic Society (311)

Abstract

Hydroxyapatite (HAp) deposition onto positively charged surfaces (i.e., self‐assembled monolayers (SAMs) terminated with NH2 head groups) and negatively charged surfaces (i.e., OH‐SAMs (weak) and COOH‐SAMs (strong)) soaked at 50°C in aqueous supersaturated solutions (1.5 SBF, pH 7.0–7.6; SBF = simulated body fluid) was investigated using a quartz‐crystal microbalance. The results revealed that the solution conditions greatly influenced the formation of HAp on the charged surfaces. In a stable supersaturated solution of simulated body fluid (1.5 SBF, pH <7.4), more strongly negative surfaces had a more powerful induction capability for the heterogeneous nucleation of HAp (COOH > OH), whereas nucleation was obviously prohibited on a positive surface (NH2‐SAM). On the other hand, after the calcium phosphate particles had nucleated homogeneously in an unstable soaking solution (1.5 SBF, pH ≧7.4), adhesion of the HAp microparticles to the NH2‐SAM was observed. A two‐step interaction is conceivable to describe the formation of HAp on the positive NH2‐SAM: At the first stage, electrostatic interaction dominates the adhesion of HAp microparticles; at the second stage, hydrogen bonds possibly form between the HAp microparticles and the amino head groups of the NH2‐SAM, for a firm bonding with the substrate, and the microparticles grow progressively into a thin film. The electrophoretic behaviors of the HAp microparticles confirmed this hypothesis.

Bibliography

Zhu, P., Masuda, Y., Yonezawa, T., & Koumoto, K. (2003). Investigation of Apatite Deposition onto Charged Surfaces in Aqueous Solutions Using a QuartzâCrystal Microbalance. Journal of the American Ceramic Society, 86(5), 782â790. Portico.

Authors 4

Peixin Zhu (first)
Yoshitake Masuda (additional)
Tetsu Yonezawa (additional)
Kunihito Koumoto (additional)

References 37 Referenced 68

10.1103/PhysRevLett.84.2997
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10.1016/0040-6031(95)02784-X
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10.1111/j.1151-2916.1999.tb02056.x
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10.1002/(SICI)1097-4636(19970305)34:3<305::AID-JBM5>3.0.CO;2-O
{'key': 'e_1_2_1_10_2', 'first-page': '423', 'article-title': 'The Nucleation and Growth of Calcium Oxalate Monohydrate on Self‐Assembled Mono‐layers (SAM)', 'volume': '7', 'author': 'Campbell A. A.', 'year': '1993', 'journal-title': 'Scanning Microsc.'} / Scanning Microsc. / The Nucleation and Growth of Calcium Oxalate Monohydrate on Self‐Assembled Mono‐layers (SAM) by Campbell A. A. (1993)
10.1002/jbm.1245
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10.1006/jcis.2001.7888
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10.1016/S0927-7765(97)00054-4
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{'key': 'e_1_2_1_29_2', 'volume-title': 'Principles of Colloid and Surface Chemistry', 'author': 'Hiemenz P. C.', 'year': '1986'} / Principles of Colloid and Surface Chemistry by Hiemenz P. C. (1986)
{'key': 'e_1_2_1_30_2', 'volume-title': 'Foundations of Colloid Science', 'author': 'Hunter R. J.', 'year': '1987'} / Foundations of Colloid Science by Hunter R. J. (1987)
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{'key': 'e_1_2_1_35_2', 'first-page': '365', 'article-title': 'Mechanisms of Growth and Dissolution of Sparingly Soluble Salts', 'volume': '23', 'author': 'Zhang J. W.', 'year': '1990', 'journal-title': 'Rev. Mineral.'} / Rev. Mineral. / Mechanisms of Growth and Dissolution of Sparingly Soluble Salts by Zhang J. W. (1990)
{'key': 'e_1_2_1_36_2', 'volume-title': 'Ion Association', 'author': 'Davies C. W.', 'year': '1962'} / Ion Association by Davies C. W. (1962)
{'key': 'e_1_2_1_37_2', 'first-page': '157', 'volume-title': 'Structure and Chemistry of the Apatites and Other Calcium Orthophosphates', 'author': 'Elliot J. C.', 'year': '1994'} / Structure and Chemistry of the Apatites and Other Calcium Orthophosphates by Elliot J. C. (1994)
10.1016/0021-9797(90)90285-V

Dates

Type	When
Created	16 years, 1 month ago (July 18, 2009, 12:27 a.m.)
Deposited	1 year, 9 months ago (Nov. 22, 2023, 8:55 p.m.)
Indexed	3 weeks, 5 days ago (Aug. 7, 2025, 4:59 p.m.)
Issued	22 years, 4 months ago (May 1, 2003)
Published	22 years, 4 months ago (May 1, 2003)
Published Online	20 years, 8 months ago (Dec. 20, 2004)
Published Print	22 years, 4 months ago (May 1, 2003)

Funders 0

None

BibTeX

@article{Zhu_2003, title={Investigation of Apatite Deposition onto Charged Surfaces in Aqueous Solutions Using a Quartz‐Crystal Microbalance}, volume={86}, ISSN={1551-2916}, url={http://dx.doi.org/10.1111/j.1151-2916.2003.tb03375.x}, DOI={10.1111/j.1151-2916.2003.tb03375.x}, number={5}, journal={Journal of the American Ceramic Society}, publisher={Wiley}, author={Zhu, Peixin and Masuda, Yoshitake and Yonezawa, Tetsu and Koumoto, Kunihito}, year={2003}, month=may, pages={782–790} }

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  "abstract": "<jats:p>Hydroxyapatite (HAp) deposition onto positively charged surfaces (i.e., self\u2010assembled monolayers (SAMs) terminated with NH<jats:sub>2</jats:sub> head groups) and negatively charged surfaces (i.e., OH\u2010SAMs (weak) and COOH\u2010SAMs (strong)) soaked at 50\u00b0C in aqueous supersaturated solutions (1.5 SBF, pH 7.0\u20137.6; SBF = simulated body fluid) was investigated using a quartz\u2010crystal microbalance. The results revealed that the solution conditions greatly influenced the formation of HAp on the charged surfaces. In a stable supersaturated solution of simulated body fluid (1.5 SBF, pH &lt;7.4), more strongly negative surfaces had a more powerful induction capability for the heterogeneous nucleation of HAp (COOH &gt; OH), whereas nucleation was obviously prohibited on a positive surface (NH<jats:sub>2</jats:sub>\u2010SAM). On the other hand, after the calcium phosphate particles had nucleated homogeneously in an unstable soaking solution (1.5 SBF, pH \u22677.4), adhesion of the HAp microparticles to the NH<jats:sub>2</jats:sub>\u2010SAM was observed. A two\u2010step interaction is conceivable to describe the formation of HAp on the positive NH<jats:sub>2</jats:sub>\u2010SAM: At the first stage, electrostatic interaction dominates the adhesion of HAp microparticles; at the second stage, hydrogen bonds possibly form between the HAp microparticles and the amino head groups of the NH<jats:sub>2</jats:sub>\u2010SAM, for a firm bonding with the substrate, and the microparticles grow progressively into a thin film. The electrophoretic behaviors of the HAp microparticles confirmed this hypothesis.</jats:p>",
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