DOI: 10.1111/j.0022-202x.2005.23733.x. Human Papillomavirus-DNA Loads in Actinic Keratoses Exceed those in Non-Melanoma Skin Cancers

Human Papillomavirus-DNA Loads in Actinic Keratoses Exceed those in Non-Melanoma Skin Cancers

10.1111/j.0022-202x.2005.23733.x

Crossref journal-article

Elsevier BV

Journal of Investigative Dermatology (78)

Bibliography

Weissenborn, S. J., Nindl, I., Purdie, K., Harwood, C., Proby, C., Breuer, J., Majewski, S., Pfister, H., & Wieland, U. (2005). Human Papillomavirus-DNA Loads in Actinic Keratoses Exceed those in Non-Melanoma Skin Cancers. Journal of Investigative Dermatology, 125(1), 93â97.

Authors 9

Soenke Jan Weissenborn (first)
Ingo Nindl (additional)
Karin Purdie (additional)
Catherine Harwood (additional)
Charlotte Proby (additional)
Judy Breuer (additional)
Slawomir Majewski (additional)
Herbert Pfister (additional)
Ulrike Wieland (additional)

References 24 Referenced 220

10.1056/NEJM200103293441306 / N Engl J Med / Cutaneous squamous-cell carcinoma by Alam (2001)
10.1067/mjd.2002.125579 / J Am Acad Dermatol / Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management by Berg (2002)
10.1099/0022-1317-79-4-779 / J Gen Virol / Detection of new human papillomavirus sequences in skin lesions of a renal transplant recipient and characterization of one complete genome related to epidermodysplasia verruciformis-associated types by Bens (1998)
10.1128/JCM.33.3.690-695.1995 / J Clin Microbiol / Nested PCR approach for detection and typing of epidermodysplasia verruciformis-associated human papillomavirus types in cutaneous cancers from renal transplant recipients by Berkhout (1995)
10.1136/jcp.55.4.244 / J Clin Pathol / The causal relation between human papillomavirus and cervical cancer by Bosch (2002)
10.1056/NEJMra022137 / N Engl J Med / Skin cancers after organ transplantation by Euvrard (2003)
{'key': '10.1111/j.0022-202X.2005.23733.x_bb0040', 'first-page': '2695', 'article-title': 'Seroreactivity to epidermodysplasia verruciformis-related human papillomavirus types is associated with nonmelanoma skin cancer', 'volume': '63', 'author': 'Feltkamp', 'year': '2003', 'journal-title': 'Cancer Res'} / Cancer Res / Seroreactivity to epidermodysplasia verruciformis-related human papillomavirus types is associated with nonmelanoma skin cancer by Feltkamp (2003)
10.1016/S0042-6822(03)00391-X / Virology / Nucleotide sequence and phylogenetic classification of candidate human papilloma virus type 92 by Forslund (2003)
10.1111/j.0022-202X.2004.23205.x / J Invest Dermatol / High prevalence of cutaneous human papillomavirus DNA on the top of skin tumors but not in “Stripped” biopsies from the same tumors by Forslund (2004)
10.1016/S0166-0934(03)00109-5 / J Virol Meth / Improved detection of cutaneous human papillomavirus DNA by single tube nested “hanging droplet” PCR by Forslund (2003)
10.1097/00001432-200204000-00002 / Curr Opin Infect Dis / Human papillomaviruses and non-melanoma skin cancer by Harwood (2002)
10.1093/emboj/cdf443 / EMBO J / Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1 by Iftner (2002)
10.1038/sj.onc.1203339 / Oncogene / E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage by Jackson (2000)
10.1111/1523-1747.ep12504887 / J Invest Dermatol / Premalignant lesions and cancers of the skin in the general population: evaluation of the role of human papillomaviruses by Kawashima (1990)
10.1001/archderm.139.7.890 / Arch Dermatol / Evidence for the association of human papillomavirus infection and cutaneous squamous cell carcinoma in immunocompetent individuals by Masini (2003)
10.1093/oxfordjournals.jncimonographs.a003483 / J Natl Cancer Inst Monographs / Human papillomavirus and skin cancer by Pfister (2003)
10.1007/s00403-003-0435-2 / Arch Dermatol Res / High prevalence of epidermodysplasia verruciformis-associated human papillomavirus in actinic keratoses by Pfister (2003)
10.1016/S0738-081X(96)00162-9 / Clin Dermatol / Role of HPV in cutaneous premalignant and malignant tumors by Pfister (1997)
10.1158/0008-5472.CAN-04-3263 / Cancer Res / Development of skin tumors in mice transgenic for early genes of human papillomavirus type 8 by Schaper (2005)
10.1128/JCM.41.6.2763-2767.2003 / J Clin Microbiol / DNA-loads of oncogenic human papillomaviruses are strongly elevated in HIV-positive women with high grade cervical lesions by Weissenborn (2003)
10.1046/j.1523-1747.2000.00069.x / J Invest Dermatol / Erythroplasia of Queyrat: Coinfection with cutaneous carcinogenic human papillomavirus type 8 and genital papillomaviruses in a carcinoma in situ by Wieland (2000)
10.1046/j.1523-1747.2000.00015.x / J Invest Dermatol / Papillomavirus DNA in basal cell carcinomas of immunocompetent patients: An accidental association? by Wieland (2000)
{'key': '10.1111/j.0022-202X.2005.23733.x_bb0120', 'first-page': '55', 'article-title': 'Papillomavirus infections—a major cause of human cancers', 'volume': '1288', 'author': 'zur Hausen', 'year': '1996', 'journal-title': 'Biochem Biophys Acta'} / Biochem Biophys Acta / Papillomavirus infections—a major cause of human cancers by zur Hausen (1996)
10.1038/nrc798 / Nat Rev Cancer / Papillomaviruses and cancer: From basic studies to clinical application by zur Hausen (2002)

Dates

Type	When
Created	20 years, 2 months ago (June 27, 2005, 11:09 a.m.)
Deposited	5 years, 4 months ago (April 7, 2020, 7:09 p.m.)
Indexed	49 minutes ago (Sept. 3, 2025, 4:25 a.m.)
Issued	20 years, 2 months ago (July 1, 2005)
Published	20 years, 2 months ago (July 1, 2005)
Published Print	20 years, 2 months ago (July 1, 2005)

Funders 0

None

BibTeX

@article{Weissenborn_2005, title={Human Papillomavirus-DNA Loads in Actinic Keratoses Exceed those in Non-Melanoma Skin Cancers}, volume={125}, ISSN={0022-202X}, url={http://dx.doi.org/10.1111/j.0022-202x.2005.23733.x}, DOI={10.1111/j.0022-202x.2005.23733.x}, number={1}, journal={Journal of Investigative Dermatology}, publisher={Elsevier BV}, author={Weissenborn, Soenke Jan and Nindl, Ingo and Purdie, Karin and Harwood, Catherine and Proby, Charlotte and Breuer, Judy and Majewski, Slawomir and Pfister, Herbert and Wieland, Ulrike}, year={2005}, month=jul, pages={93–97} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        9,
        3
      ]
    ],
    "date-time": "2025-09-03T08:25:51Z",
    "timestamp": 1756887951252
  },
  "reference-count": 24,
  "publisher": "Elsevier BV",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2005,
            7,
            1
          ]
        ],
        "date-time": "2005-07-01T00:00:00Z",
        "timestamp": 1120176000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2015,
            12,
            2
          ]
        ],
        "date-time": "2015-12-02T00:00:00Z",
        "timestamp": 1449014400000
      },
      "content-version": "vor",
      "delay-in-days": 3806,
      "URL": "https://www.elsevier.com/open-access/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2005,
        7
      ]
    ]
  },
  "DOI": "10.1111/j.0022-202x.2005.23733.x",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        6,
        27
      ]
    ],
    "date-time": "2005-06-27T15:09:24Z",
    "timestamp": 1119884964000
  },
  "page": "93-97",
  "source": "Crossref",
  "is-referenced-by-count": 220,
  "title": "Human Papillomavirus-DNA Loads in Actinic Keratoses Exceed those in Non-Melanoma Skin Cancers",
  "prefix": "10.1016",
  "volume": "125",
  "author": [
    {
      "given": "Soenke Jan",
      "family": "Weissenborn",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Ingo",
      "family": "Nindl",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Karin",
      "family": "Purdie",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Catherine",
      "family": "Harwood",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Charlotte",
      "family": "Proby",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Judy",
      "family": "Breuer",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Slawomir",
      "family": "Majewski",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Herbert",
      "family": "Pfister",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Ulrike",
      "family": "Wieland",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0010",
      "doi-asserted-by": "crossref",
      "first-page": "975",
      "DOI": "10.1056/NEJM200103293441306",
      "article-title": "Cutaneous squamous-cell carcinoma",
      "volume": "344",
      "author": "Alam",
      "year": "2001",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0015",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1067/mjd.2002.125579",
      "article-title": "Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management",
      "volume": "47",
      "author": "Berg",
      "year": "2002",
      "journal-title": "J Am Acad Dermatol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0020",
      "doi-asserted-by": "crossref",
      "first-page": "779",
      "DOI": "10.1099/0022-1317-79-4-779",
      "article-title": "Detection of new human papillomavirus sequences in skin lesions of a renal transplant recipient and characterization of one complete genome related to epidermodysplasia verruciformis-associated types",
      "volume": "79",
      "author": "Bens",
      "year": "1998",
      "journal-title": "J Gen Virol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0025",
      "doi-asserted-by": "crossref",
      "first-page": "690",
      "DOI": "10.1128/JCM.33.3.690-695.1995",
      "article-title": "Nested PCR approach for detection and typing of epidermodysplasia verruciformis-associated human papillomavirus types in cutaneous cancers from renal transplant recipients",
      "volume": "33",
      "author": "Berkhout",
      "year": "1995",
      "journal-title": "J Clin Microbiol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0030",
      "doi-asserted-by": "crossref",
      "first-page": "244",
      "DOI": "10.1136/jcp.55.4.244",
      "article-title": "The causal relation between human papillomavirus and cervical cancer",
      "volume": "55",
      "author": "Bosch",
      "year": "2002",
      "journal-title": "J Clin Pathol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0035",
      "doi-asserted-by": "crossref",
      "first-page": "1681",
      "DOI": "10.1056/NEJMra022137",
      "article-title": "Skin cancers after organ transplantation",
      "volume": "348",
      "author": "Euvrard",
      "year": "2003",
      "journal-title": "N Engl J Med"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0040",
      "first-page": "2695",
      "article-title": "Seroreactivity to epidermodysplasia verruciformis-related human papillomavirus types is associated with nonmelanoma skin cancer",
      "volume": "63",
      "author": "Feltkamp",
      "year": "2003",
      "journal-title": "Cancer Res"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0045",
      "doi-asserted-by": "crossref",
      "first-page": "255",
      "DOI": "10.1016/S0042-6822(03)00391-X",
      "article-title": "Nucleotide sequence and phylogenetic classification of candidate human papilloma virus type 92",
      "volume": "312",
      "author": "Forslund",
      "year": "2003",
      "journal-title": "Virology"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0050",
      "doi-asserted-by": "crossref",
      "first-page": "388",
      "DOI": "10.1111/j.0022-202X.2004.23205.x",
      "article-title": "High prevalence of cutaneous human papillomavirus DNA on the top of skin tumors but not in \u201cStripped\u201d biopsies from the same tumors",
      "volume": "123",
      "author": "Forslund",
      "year": "2004",
      "journal-title": "J Invest Dermatol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0055",
      "doi-asserted-by": "crossref",
      "first-page": "129",
      "DOI": "10.1016/S0166-0934(03)00109-5",
      "article-title": "Improved detection of cutaneous human papillomavirus DNA by single tube nested \u201changing droplet\u201d PCR",
      "volume": "110",
      "author": "Forslund",
      "year": "2003",
      "journal-title": "J Virol Meth"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0060",
      "doi-asserted-by": "crossref",
      "first-page": "101",
      "DOI": "10.1097/00001432-200204000-00002",
      "article-title": "Human papillomaviruses and non-melanoma skin cancer",
      "volume": "15",
      "author": "Harwood",
      "year": "2002",
      "journal-title": "Curr Opin Infect Dis"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0065",
      "doi-asserted-by": "crossref",
      "first-page": "4741",
      "DOI": "10.1093/emboj/cdf443",
      "article-title": "Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1",
      "volume": "21",
      "author": "Iftner",
      "year": "2002",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0070",
      "doi-asserted-by": "crossref",
      "first-page": "592",
      "DOI": "10.1038/sj.onc.1203339",
      "article-title": "E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage",
      "volume": "19",
      "author": "Jackson",
      "year": "2000",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0075",
      "doi-asserted-by": "crossref",
      "first-page": "537",
      "DOI": "10.1111/1523-1747.ep12504887",
      "article-title": "Premalignant lesions and cancers of the skin in the general population: evaluation of the role of human papillomaviruses",
      "volume": "95",
      "author": "Kawashima",
      "year": "1990",
      "journal-title": "J Invest Dermatol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0080",
      "doi-asserted-by": "crossref",
      "first-page": "890",
      "DOI": "10.1001/archderm.139.7.890",
      "article-title": "Evidence for the association of human papillomavirus infection and cutaneous squamous cell carcinoma in immunocompetent individuals",
      "volume": "139",
      "author": "Masini",
      "year": "2003",
      "journal-title": "Arch Dermatol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0085",
      "doi-asserted-by": "crossref",
      "first-page": "52",
      "DOI": "10.1093/oxfordjournals.jncimonographs.a003483",
      "article-title": "Human papillomavirus and skin cancer",
      "volume": "31",
      "author": "Pfister",
      "year": "2003",
      "journal-title": "J Natl Cancer Inst Monographs"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0090",
      "doi-asserted-by": "crossref",
      "first-page": "273",
      "DOI": "10.1007/s00403-003-0435-2",
      "article-title": "High prevalence of epidermodysplasia verruciformis-associated human papillomavirus in actinic keratoses",
      "volume": "295",
      "author": "Pfister",
      "year": "2003",
      "journal-title": "Arch Dermatol Res"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0095",
      "doi-asserted-by": "crossref",
      "first-page": "335",
      "DOI": "10.1016/S0738-081X(96)00162-9",
      "article-title": "Role of HPV in cutaneous premalignant and malignant tumors",
      "volume": "15",
      "author": "Pfister",
      "year": "1997",
      "journal-title": "Clin Dermatol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0100",
      "doi-asserted-by": "crossref",
      "first-page": "1394",
      "DOI": "10.1158/0008-5472.CAN-04-3263",
      "article-title": "Development of skin tumors in mice transgenic for early genes of human papillomavirus type 8",
      "volume": "65",
      "author": "Schaper",
      "year": "2005",
      "journal-title": "Cancer Res"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0105",
      "doi-asserted-by": "crossref",
      "first-page": "2763",
      "DOI": "10.1128/JCM.41.6.2763-2767.2003",
      "article-title": "DNA-loads of oncogenic human papillomaviruses are strongly elevated in HIV-positive women with high grade cervical lesions",
      "volume": "41",
      "author": "Weissenborn",
      "year": "2003",
      "journal-title": "J Clin Microbiol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0110",
      "doi-asserted-by": "crossref",
      "first-page": "396",
      "DOI": "10.1046/j.1523-1747.2000.00069.x",
      "article-title": "Erythroplasia of Queyrat: Coinfection with cutaneous carcinogenic human papillomavirus type 8 and genital papillomaviruses in a carcinoma in situ",
      "volume": "115",
      "author": "Wieland",
      "year": "2000",
      "journal-title": "J Invest Dermatol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0115",
      "doi-asserted-by": "crossref",
      "first-page": "124",
      "DOI": "10.1046/j.1523-1747.2000.00015.x",
      "article-title": "Papillomavirus DNA in basal cell carcinomas of immunocompetent patients: An accidental association?",
      "volume": "115",
      "author": "Wieland",
      "year": "2000",
      "journal-title": "J Invest Dermatol"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0120",
      "first-page": "55",
      "article-title": "Papillomavirus infections\u2014a major cause of human cancers",
      "volume": "1288",
      "author": "zur Hausen",
      "year": "1996",
      "journal-title": "Biochem Biophys Acta"
    },
    {
      "key": "10.1111/j.0022-202X.2005.23733.x_bb0125",
      "doi-asserted-by": "crossref",
      "first-page": "342",
      "DOI": "10.1038/nrc798",
      "article-title": "Papillomaviruses and cancer: From basic studies to clinical application",
      "volume": "2",
      "author": "zur Hausen",
      "year": "2002",
      "journal-title": "Nat Rev Cancer"
    }
  ],
  "container-title": "Journal of Investigative Dermatology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0022202X15323411?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0022202X15323411?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2020,
        4,
        7
      ]
    ],
    "date-time": "2020-04-07T23:09:04Z",
    "timestamp": 1586300944000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0022202X15323411"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2005,
        7
      ]
    ]
  },
  "references-count": 24,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          2005,
          7
        ]
      ]
    }
  },
  "alternative-id": [
    "S0022202X15323411"
  ],
  "URL": "http://dx.doi.org/10.1111/j.0022-202X.2005.23733.x",
  "relation": {},
  "ISSN": [
    "0022-202X"
  ],
  "subject": [],
  "container-title-short": "Journal of Investigative Dermatology",
  "published": {
    "date-parts": [
      [
        2005,
        7
      ]
    ]
  }
}