DOI: 10.1110/ps.9.10.1930. The PA domain: A protease‐associated domain

The PA domain: A protease‐associated domain

10.1110/ps.9.10.1930

Crossref journal-article

Wiley

Protein Science (311)

Abstract

AbstractWe have identified a similarity between the apical domain of the human transferrin receptor and several other protein families. This domain is found associated with two different families of peptidases. Therefore, we term it the PA domain for protease‐associated domain. The PA domain is found inserted within a loop of the peptidase domain of family M8/M33 zinc peptidases. The PA domain is also found in a vacuolar sorting receptor and a ring finger protein of unknown function that may be a cell surface receptor. The PA domain may mediate substrate determination of peptidases or form protein‐protein interactions.

Bibliography

Mahon, P., & Bateman, A. (2000). The PA domain: A proteaseâassociated domain. Protein Science, 9(10), 1930â1934. Portico.

Authors 2

Piers Mahon (first)
Alex Bateman (additional)

References 20 Referenced 89

10.1093/nar/25.17.3389
10.1006/jtbi.1995.0073
10.1093/protein/7.8.991
10.1016/0076-6879(94)28019-3
10.1016/S0021-9258(19)39748-0 / J Biol Chem / Complete nucleotide sequence of the streptococcal C5a peptidase gene of Streptococcus pyogenes by Chen CC (1990)
10.1016/S0090-4295(97)00177-5
{'key': 'e_1_2_1_8_1', 'first-page': '166', 'article-title': 'TMbase—A database of membrane spanning proteins segments', 'volume': '347', 'author': 'Hofmann K', 'year': '1993', 'journal-title': 'Biol Chem Hoppe‐Seyler'} / Biol Chem Hoppe‐Seyler / TMbase—A database of membrane spanning proteins segments by Hofmann K (1993)
10.1128/iai.64.2.503-510.1996 / Infect Immunity / C5a peptidase alters clearance and trafficking of group A streptococci by infected mice by Ji YD (1996)
10.1073/pnas.91.8.3403
10.1104/pp.111.2.469
10.1107/S0021889891004399
10.1126/science.286.5440.779
10.1093/protein/12.1.3
10.1104/pp.115.1.29
10.1016/S0167-4838(97)00008-3
10.1073/pnas.95.17.9920
10.1023/A:1002036906922
10.1002/pro.5560060301
{'key': 'e_1_2_1_20_1', 'first-page': '1441', 'article-title': 'Alternatively spliced variants of prostate‐specific membrane antigen RNA: Ratio of expression as a potential measurement of progression', 'volume': '55', 'author': 'Su SL', 'year': '1995', 'journal-title': 'Cancer Res'} / Cancer Res / Alternatively spliced variants of prostate‐specific membrane antigen RNA: Ratio of expression as a potential measurement of progression by Su SL (1995)
10.1073/pnas.93.7.3105

Dates

Type	When
Created	16 years, 6 months ago (Feb. 17, 2009, 5:31 p.m.)
Deposited	1 year, 9 months ago (Oct. 29, 2023, 1:37 p.m.)
Indexed	1 month ago (July 24, 2025, 7:28 a.m.)
Issued	25 years, 7 months ago (Jan. 1, 2000)
Published	25 years, 7 months ago (Jan. 1, 2000)
Published Online	16 years, 7 months ago (Dec. 31, 2008)
Published Print	25 years, 7 months ago (Jan. 1, 2000)

Funders 0

None

BibTeX

@article{Mahon_2000, title={The PA domain: A protease‐associated domain}, volume={9}, ISSN={1469-896X}, url={http://dx.doi.org/10.1110/ps.9.10.1930}, DOI={10.1110/ps.9.10.1930}, number={10}, journal={Protein Science}, publisher={Wiley}, author={Mahon, Piers and Bateman, Alex}, year={2000}, month=jan, pages={1930–1934} }

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