DOI: 10.1107/s1399004714014795. Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the program<i>Zanuda</i>

Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the programZanuda

10.1107/s1399004714014795

Crossref journal-article

International Union of Crystallography (IUCr)

Acta Crystallographica Section D Biological Crystallography (329)

Abstract

The presence of pseudo-symmetry in a macromolecular crystal and its interplay with twinning may lead to an incorrect space-group (SG) assignment. Moreover, if the pseudo-symmetry is very close to an exact crystallographic symmetry, the structure can be solved and partially refined in the wrong SG. Typically, in such incorrectly determined structures all or some of the pseudo-symmetry operations are, in effect, taken for crystallographic symmetry operations andvice versa. A mistake only becomes apparent when theRfreeceases to decrease below 0.39 and further model rebuilding and refinement cannot improve the refinement statistics. If pseudo-symmetry includes pseudo-translation, the uncertainty in SG assignment may be associated with an incorrect choice of origin, as demonstrated by the series of examples provided here. The programZanudapresented in this article was developed for the automation of SG validation.Zanudaruns a series of refinements in SGs compatible with the observed unit-cell parameters and chooses the model with the highest symmetry SG from a subset of models that have the best refinement statistics.

Bibliography

Lebedev, A. A., & Isupov, M. N. (2014). Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the programZanuda. Acta Crystallographica Section D Biological Crystallography, 70(9), 2430â2443.

Authors 2

Andrey A. Lebedev (first)
Michail N. Isupov (additional)

References 44 Referenced 94

10.1107/S0907444906033555 / Acta Cryst. D by Au (2006)
10.1038/355472a0 / Nature (London) by Brünger (1992)
10.1016/S0076-6879(97)76065-8 / Methods Enzymol. by Carter (1997)
10.1107/S090744490903947X / Acta Cryst. D by Cowtan (2010)
10.1107/S0365110X67003172 / Acta Cryst. by Crowther (1967)
10.1107/S0907444905011285 / Acta Cryst. D by Dauter (2005)
DeLano, W. L. (2002). PyMOL. http://www.pymol.org.
10.1107/S0907444910007493 / Acta Cryst. D by Emsley (2010)
10.1107/S0907444905036693 / Acta Cryst. D by Evans (2006)
10.1107/S090744491003982X / Acta Cryst. D by Evans (2011)
10.1107/S0907444913000061 / Acta Cryst. D by Evans (2013)
10.1098/rspa.1954.0203 / Proc. R. Soc. Lond. A by Green (1954)
10.1107/S0907444907053802 / Acta Cryst. D by Isupov (2008)
10.1107/S0567739476001873 / Acta Cryst. A by Kabsch (1976)
10.1107/S0907444909047337 / Acta Cryst. D by Kabsch (2010)
Lebedev, A. A. & Isupov, M. N. (2012). CCP4 Newsl. Protein Crystallogr. 48, contribution 11.
10.1107/S0907444905036759 / Acta Cryst. D by Lebedev (2006)
10.1107/S0907444903019942 / Acta Cryst. D by Lee (2003)
Leslie, A. G. W. & Powell, H. R. (2007). Evolving Methods for Macromolecular Crystallography, edited by R. J. Read & J. L. Sussman, pp. 41-51. Dordrecht: Springer.
10.1016/j.jmb.2009.05.077 / J. Mol. Biol. by Levdikov (2009)
10.1074/jbc.M513015200 / J. Biol. Chem. by Levdikov (2006)
10.1107/S0021889807021206 / J. Appl. Cryst. by McCoy (2007)
10.1107/S0907444911001314 / Acta Cryst. D by Murshudov (2011)
10.1016/S0076-6879(97)76066-X / Methods Enzymol. by Otwinowski (1997)
10.1107/S0907444903007947 / Acta Cryst. D by Padilla (2003)
10.1107/S0907444998004119 / Acta Cryst. D by Pannu (1998)
10.1107/S0907444909020927 / Acta Cryst. D by Pletnev (2009)
10.1107/S0907444903008126 / Acta Cryst. D by Potterton (2003)
10.1107/S0907444912048524 / Acta Cryst. D by Powell (2013)
Rossman, M. G. (1972). Editor. The Molecular Replacement Method. New York: Gordon & Breach.
10.1107/S0907444907026315 / Acta Cryst. D by Rye (2007)
10.1107/S0907444912051670 / Acta Cryst. D by Sayer (2013)
10.1107/S0907444909038360 / Acta Cryst. D by Sheldrick (2010)
10.1016/j.jsb.2010.01.013 / J. Struct. Biol. by Shevtsov (2010)
10.1038/ncomms3777 / Nature Commun. by Skubák (2013)
10.1107/S0907444901007673 / Acta Cryst. D by Trame (2001)
10.1107/S0907444901012409 / Acta Cryst. D by Vagin (2001)
10.1107/S0907444900013780 / Acta Cryst. D by Vagin (2000)
10.1107/S0907444909042589 / Acta Cryst. D by Vagin (2010)
{'key': 'dz5330_bb39', 'first-page': '215', 'volume': '364', 'author': 'Vonrhein', 'year': '2007', 'journal-title': 'Methods Mol. Biol.'} / Methods Mol. Biol. by Vonrhein (2007)
10.1074/jbc.M111.226142 / J. Biol. Chem. by Watson (2011)
10.1107/S0907444910045749 / Acta Cryst. D by Winn (2011)
10.1107/S0021889809045701 / J. Appl. Cryst. by Winter (2010)
10.1107/S0108767387009632 / Acta Cryst. A by Yeates (1988)

Dates

Type	When
Created	10 years, 11 months ago (Aug. 29, 2014, 11:20 a.m.)
Deposited	7 months, 1 week ago (Jan. 13, 2025, 4:54 a.m.)
Indexed	5 days, 5 hours ago (Aug. 20, 2025, 8:58 a.m.)
Issued	10 years, 11 months ago (Aug. 29, 2014)
Published	10 years, 11 months ago (Aug. 29, 2014)
Published Online	10 years, 11 months ago (Aug. 29, 2014)
Published Print	10 years, 11 months ago (Sept. 1, 2014)

Funders 0

None

BibTeX

@article{Lebedev_2014, title={Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the programZanuda}, volume={70}, ISSN={1399-0047}, url={http://dx.doi.org/10.1107/s1399004714014795}, DOI={10.1107/s1399004714014795}, number={9}, journal={Acta Crystallographica Section D Biological Crystallography}, publisher={International Union of Crystallography (IUCr)}, author={Lebedev, Andrey A. and Isupov, Michail N.}, year={2014}, month=aug, pages={2430–2443} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        20
      ]
    ],
    "date-time": "2025-08-20T12:58:19Z",
    "timestamp": 1755694699598,
    "version": "3.33.0"
  },
  "reference-count": 44,
  "publisher": "International Union of Crystallography (IUCr)",
  "issue": "9",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2014,
            8,
            29
          ]
        ],
        "date-time": "2014-08-29T00:00:00Z",
        "timestamp": 1409270400000
      },
      "content-version": "vor",
      "delay-in-days": 0,
      "URL": "http://journals.iucr.org/services/copyrightpolicy.html"
    },
    {
      "start": {
        "date-parts": [
          [
            2014,
            8,
            29
          ]
        ],
        "date-time": "2014-08-29T00:00:00Z",
        "timestamp": 1409270400000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "http://journals.iucr.org/services/copyrightpolicy.html#TDM"
    }
  ],
  "content-domain": {
    "domain": [
      "iucr.org",
      "wiley.com",
      "iucrj.org"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        2014,
        9,
        1
      ]
    ]
  },
  "abstract": "<jats:p>The presence of pseudo-symmetry in a macromolecular crystal and its interplay with twinning may lead to an incorrect space-group (SG) assignment. Moreover, if the pseudo-symmetry is very close to an exact crystallographic symmetry, the structure can be solved and partially refined in the wrong SG. Typically, in such incorrectly determined structures all or some of the pseudo-symmetry operations are, in effect, taken for crystallographic symmetry operations and<jats:italic>vice versa</jats:italic>. A mistake only becomes apparent when the<jats:italic>R</jats:italic><jats:sub>free</jats:sub>ceases to decrease below 0.39 and further model rebuilding and refinement cannot improve the refinement statistics. If pseudo-symmetry includes pseudo-translation, the uncertainty in SG assignment may be associated with an incorrect choice of origin, as demonstrated by the series of examples provided here. The program<jats:italic>Zanuda</jats:italic>presented in this article was developed for the automation of SG validation.<jats:italic>Zanuda</jats:italic>runs a series of refinements in SGs compatible with the observed unit-cell parameters and chooses the model with the highest symmetry SG from a subset of models that have the best refinement statistics.</jats:p>",
  "DOI": "10.1107/s1399004714014795",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2014,
        8,
        29
      ]
    ],
    "date-time": "2014-08-29T15:20:19Z",
    "timestamp": 1409325619000
  },
  "page": "2430-2443",
  "update-policy": "https://doi.org/10.1107/cm_01",
  "source": "Crossref",
  "is-referenced-by-count": 94,
  "title": "Space-group and origin ambiguity in macromolecular structures with pseudo-symmetry and its treatment with the program<i>Zanuda</i>",
  "prefix": "10.1107",
  "volume": "70",
  "author": [
    {
      "given": "Andrey A.",
      "family": "Lebedev",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Michail N.",
      "family": "Isupov",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "329",
  "published-online": {
    "date-parts": [
      [
        2014,
        8,
        29
      ]
    ]
  },
  "reference": [
    {
      "key": "dz5330_bb1",
      "doi-asserted-by": "crossref",
      "first-page": "1267",
      "DOI": "10.1107/S0907444906033555",
      "volume": "62",
      "author": "Au",
      "year": "2006",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb2",
      "doi-asserted-by": "crossref",
      "first-page": "472",
      "DOI": "10.1038/355472a0",
      "volume": "355",
      "author": "Br\u00fcnger",
      "year": "1992",
      "journal-title": "Nature (London)"
    },
    {
      "key": "dz5330_bb3",
      "doi-asserted-by": "crossref",
      "first-page": "286",
      "DOI": "10.1016/S0076-6879(97)76065-8",
      "volume": "276",
      "author": "Carter",
      "year": "1997",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "dz5330_bb4",
      "doi-asserted-by": "crossref",
      "first-page": "470",
      "DOI": "10.1107/S090744490903947X",
      "volume": "66",
      "author": "Cowtan",
      "year": "2010",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb5",
      "doi-asserted-by": "crossref",
      "first-page": "544",
      "DOI": "10.1107/S0365110X67003172",
      "volume": "23",
      "author": "Crowther",
      "year": "1967",
      "journal-title": "Acta Cryst."
    },
    {
      "key": "dz5330_bb6",
      "doi-asserted-by": "crossref",
      "first-page": "967",
      "DOI": "10.1107/S0907444905011285",
      "volume": "61",
      "author": "Dauter",
      "year": "2005",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb7",
      "unstructured": "DeLano, W. L. (2002). PyMOL. http://www.pymol.org."
    },
    {
      "key": "dz5330_bb8",
      "doi-asserted-by": "crossref",
      "first-page": "486",
      "DOI": "10.1107/S0907444910007493",
      "volume": "66",
      "author": "Emsley",
      "year": "2010",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb9",
      "doi-asserted-by": "crossref",
      "first-page": "72",
      "DOI": "10.1107/S0907444905036693",
      "volume": "62",
      "author": "Evans",
      "year": "2006",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb10",
      "doi-asserted-by": "crossref",
      "first-page": "282",
      "DOI": "10.1107/S090744491003982X",
      "volume": "67",
      "author": "Evans",
      "year": "2011",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb11",
      "doi-asserted-by": "crossref",
      "first-page": "1204",
      "DOI": "10.1107/S0907444913000061",
      "volume": "69",
      "author": "Evans",
      "year": "2013",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb12",
      "doi-asserted-by": "crossref",
      "first-page": "287",
      "DOI": "10.1098/rspa.1954.0203",
      "volume": "225",
      "author": "Green",
      "year": "1954",
      "journal-title": "Proc. R. Soc. Lond. A"
    },
    {
      "key": "dz5330_bb13",
      "doi-asserted-by": "crossref",
      "first-page": "90",
      "DOI": "10.1107/S0907444907053802",
      "volume": "64",
      "author": "Isupov",
      "year": "2008",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb14",
      "doi-asserted-by": "crossref",
      "first-page": "922",
      "DOI": "10.1107/S0567739476001873",
      "volume": "32",
      "author": "Kabsch",
      "year": "1976",
      "journal-title": "Acta Cryst. A"
    },
    {
      "key": "dz5330_bb15",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1107/S0907444909047337",
      "volume": "66",
      "author": "Kabsch",
      "year": "2010",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb16",
      "unstructured": "Lebedev, A. A. & Isupov, M. N. (2012). CCP4 Newsl. Protein Crystallogr. 48, contribution 11."
    },
    {
      "key": "dz5330_bb17",
      "doi-asserted-by": "crossref",
      "first-page": "83",
      "DOI": "10.1107/S0907444905036759",
      "volume": "62",
      "author": "Lebedev",
      "year": "2006",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb18",
      "doi-asserted-by": "crossref",
      "first-page": "2191",
      "DOI": "10.1107/S0907444903019942",
      "volume": "59",
      "author": "Lee",
      "year": "2003",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb19",
      "unstructured": "Leslie, A. G. W. & Powell, H. R. (2007). Evolving Methods for Macromolecular Crystallography, edited by R. J. Read & J. L. Sussman, pp. 41-51. Dordrecht: Springer."
    },
    {
      "key": "dz5330_bb20",
      "doi-asserted-by": "crossref",
      "first-page": "1007",
      "DOI": "10.1016/j.jmb.2009.05.077",
      "volume": "390",
      "author": "Levdikov",
      "year": "2009",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "dz5330_bb21",
      "doi-asserted-by": "crossref",
      "first-page": "11366",
      "DOI": "10.1074/jbc.M513015200",
      "volume": "281",
      "author": "Levdikov",
      "year": "2006",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "dz5330_bb22",
      "doi-asserted-by": "crossref",
      "first-page": "658",
      "DOI": "10.1107/S0021889807021206",
      "volume": "40",
      "author": "McCoy",
      "year": "2007",
      "journal-title": "J. Appl. Cryst."
    },
    {
      "key": "dz5330_bb23",
      "doi-asserted-by": "crossref",
      "first-page": "355",
      "DOI": "10.1107/S0907444911001314",
      "volume": "67",
      "author": "Murshudov",
      "year": "2011",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb24",
      "doi-asserted-by": "crossref",
      "first-page": "307",
      "DOI": "10.1016/S0076-6879(97)76066-X",
      "volume": "276",
      "author": "Otwinowski",
      "year": "1997",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "dz5330_bb25",
      "doi-asserted-by": "crossref",
      "first-page": "1124",
      "DOI": "10.1107/S0907444903007947",
      "volume": "59",
      "author": "Padilla",
      "year": "2003",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb26",
      "doi-asserted-by": "crossref",
      "first-page": "1285",
      "DOI": "10.1107/S0907444998004119",
      "volume": "54",
      "author": "Pannu",
      "year": "1998",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb27",
      "doi-asserted-by": "crossref",
      "first-page": "906",
      "DOI": "10.1107/S0907444909020927",
      "volume": "65",
      "author": "Pletnev",
      "year": "2009",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb28",
      "doi-asserted-by": "crossref",
      "first-page": "1131",
      "DOI": "10.1107/S0907444903008126",
      "volume": "59",
      "author": "Potterton",
      "year": "2003",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb29",
      "doi-asserted-by": "crossref",
      "first-page": "1195",
      "DOI": "10.1107/S0907444912048524",
      "volume": "69",
      "author": "Powell",
      "year": "2013",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb30",
      "unstructured": "Rossman, M. G. (1972). Editor. The Molecular Replacement Method. New York: Gordon & Breach."
    },
    {
      "key": "dz5330_bb31",
      "doi-asserted-by": "crossref",
      "first-page": "926",
      "DOI": "10.1107/S0907444907026315",
      "volume": "63",
      "author": "Rye",
      "year": "2007",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb32",
      "doi-asserted-by": "crossref",
      "first-page": "564",
      "DOI": "10.1107/S0907444912051670",
      "volume": "69",
      "author": "Sayer",
      "year": "2013",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb33",
      "doi-asserted-by": "crossref",
      "first-page": "479",
      "DOI": "10.1107/S0907444909038360",
      "volume": "66",
      "author": "Sheldrick",
      "year": "2010",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb34",
      "doi-asserted-by": "crossref",
      "first-page": "127",
      "DOI": "10.1016/j.jsb.2010.01.013",
      "volume": "170",
      "author": "Shevtsov",
      "year": "2010",
      "journal-title": "J. Struct. Biol."
    },
    {
      "key": "dz5330_bb35",
      "doi-asserted-by": "crossref",
      "first-page": "2777",
      "DOI": "10.1038/ncomms3777",
      "volume": "4",
      "author": "Skub\u00e1k",
      "year": "2013",
      "journal-title": "Nature Commun."
    },
    {
      "key": "dz5330_bb36",
      "doi-asserted-by": "crossref",
      "first-page": "1079",
      "DOI": "10.1107/S0907444901007673",
      "volume": "57",
      "author": "Trame",
      "year": "2001",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb37",
      "doi-asserted-by": "crossref",
      "first-page": "1451",
      "DOI": "10.1107/S0907444901012409",
      "volume": "57",
      "author": "Vagin",
      "year": "2001",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb38",
      "doi-asserted-by": "crossref",
      "first-page": "1622",
      "DOI": "10.1107/S0907444900013780",
      "volume": "56",
      "author": "Vagin",
      "year": "2000",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb44",
      "doi-asserted-by": "crossref",
      "first-page": "22",
      "DOI": "10.1107/S0907444909042589",
      "volume": "66",
      "author": "Vagin",
      "year": "2010",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb39",
      "first-page": "215",
      "volume": "364",
      "author": "Vonrhein",
      "year": "2007",
      "journal-title": "Methods Mol. Biol."
    },
    {
      "key": "dz5330_bb40",
      "doi-asserted-by": "crossref",
      "first-page": "24208",
      "DOI": "10.1074/jbc.M111.226142",
      "volume": "286",
      "author": "Watson",
      "year": "2011",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "dz5330_bb41",
      "doi-asserted-by": "crossref",
      "first-page": "235",
      "DOI": "10.1107/S0907444910045749",
      "volume": "67",
      "author": "Winn",
      "year": "2011",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "dz5330_bb42",
      "doi-asserted-by": "crossref",
      "first-page": "186",
      "DOI": "10.1107/S0021889809045701",
      "volume": "43",
      "author": "Winter",
      "year": "2010",
      "journal-title": "J. Appl. Cryst."
    },
    {
      "key": "dz5330_bb43",
      "doi-asserted-by": "crossref",
      "first-page": "142",
      "DOI": "10.1107/S0108767387009632",
      "volume": "44",
      "author": "Yeates",
      "year": "1988",
      "journal-title": "Acta Cryst. A"
    }
  ],
  "container-title": "Acta Crystallographica Section D Biological Crystallography",
  "original-title": [],
  "link": [
    {
      "URL": "http://journals.iucr.org/d/issues/2014/09/00/dz5330/dz5330.pdf",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://journals.iucr.org/d/issues/2014/09/00/dz5330/dz5330.pdf",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2025,
        1,
        13
      ]
    ],
    "date-time": "2025-01-13T09:54:25Z",
    "timestamp": 1736762065000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://journals.iucr.org/paper?S1399004714014795"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2014,
        8,
        29
      ]
    ]
  },
  "references-count": 44,
  "journal-issue": {
    "issue": "9",
    "published-online": {
      "date-parts": [
        [
          2014,
          9
        ]
      ]
    }
  },
  "alternative-id": [
    "S1399004714014795"
  ],
  "URL": "http://dx.doi.org/10.1107/S1399004714014795",
  "relation": {},
  "ISSN": [
    "1399-0047"
  ],
  "subject": [],
  "container-title-short": "Acta Crystallogr D Biol Crystallogr",
  "published": {
    "date-parts": [
      [
        2014,
        8,
        29
      ]
    ]
  },
  "assertion": [
    {
      "value": "Acta Crystallographica Section D: Biological Crystallography",
      "name": "journal",
      "label": "Journal",
      "explanation": {
        "URL": "http://journals.iucr.org/d"
      }
    },
    {
      "value": "research papers",
      "name": "content_type",
      "label": "Content type",
      "explanation": {
        "URL": "http://journals.iucr.org/d/issues/2011/01/00/me0434/index.html"
      }
    },
    {
      "value": "Yes",
      "order": 0,
      "name": "peer_reviewed",
      "label": "Peer reviewed",
      "group": {
        "name": "peer_review",
        "label": "Peer review"
      }
    },
    {
      "value": "Single blind",
      "order": 1,
      "name": "review_process",
      "label": "Review process",
      "group": {
        "name": "peer_review",
        "label": "Peer review"
      }
    },
    {
      "value": "4 April 2014",
      "order": 0,
      "name": "received",
      "label": "Received",
      "group": {
        "name": "publication_history",
        "label": "Publication history"
      }
    },
    {
      "value": "23 June 2014",
      "order": 1,
      "name": "accepted",
      "label": "Accepted",
      "group": {
        "name": "publication_history",
        "label": "Publication history"
      }
    },
    {
      "value": "29 August 2014",
      "order": 2,
      "name": "published_online",
      "label": "Published online",
      "group": {
        "name": "publication_history",
        "label": "Publication history"
      }
    },
    {
      "value": "\u00a9 2014 International Union of Crystallography",
      "order": 0,
      "name": "copyright",
      "label": "Copyright",
      "explanation": {
        "URL": "http://journals.iucr.org/services/copyrightpolicy.html"
      },
      "group": {
        "name": "copyright_and_licensing",
        "label": "Copyright and licencing"
      }
    }
  ]
}