DOI: 10.1101/lm.253506. Two mutations preventing PDZ–protein interactions of GluR1 have opposite effects on synaptic plasticity

Two mutations preventing PDZ–protein interactions of GluR1 have opposite effects on synaptic plasticity

10.1101/lm.253506

Crossref journal-article

Cold Spring Harbor Laboratory

Learning & Memory (246)

Abstract

The regulated trafficking of GluR1 contributes significantly to synaptic plasticity, but studies addressing the function of the GluR1 C-terminal PDZ-ligand domain in this process have produced conflicting results. Here, we resolve this conflict by showing that apparently similar C-terminal mutations of the GluR1 PDZ-ligand domain result in opposite physiological phenotypes during activity- and CamKII-induced synaptic plasticity.

Bibliography

Boehm, J., Ehrlich, I., Hsieh, H., & Malinow, R. (2006). Two mutations preventing PDZâprotein interactions of GluR1 have opposite effects on synaptic plasticity. Learning & Memory, 13(5), 562â565.

Authors 4

Jannic Boehm (first)
Ingrid Ehrlich (additional)
Helen Hsieh (additional)
Roberto Malinow (additional)

References 26 Referenced 17

10.1016/j.neuron.2005.08.034
10.1016/S0896-6273(03)00640-8
10.1016/j.neuron.2004.12.023
10.1074/jbc.M204354200
10.1242/jcs.02320
10.1523/JNEUROSCI.20-19-07258.2000 / J. Neurosci. / Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins by Chung, (2000)
10.1016/S0962-8924(00)01783-9
10.1126/science.287.5461.2262
10.1038/nrn1517
10.1038/nn1432
10.1016/S0896-6273(02)01024-3
10.1074/jbc.273.31.19518
10.1016/j.neuron.2005.07.006
10.1146/annurev.neuro.25.112701.142758
10.1038/nn0901-917
10.1523/JNEUROSCI.22-13-05387.2002 / J. Neurosci. / Critical postsynaptic density 95/disc large/zonula occludens-1 interactions by glutamate receptor 1 (GluR1) and GluR2 required at different subcellular sites by Piccini, (2002)
10.1523/JNEUROSCI.22-11-04406.2002 / J. Neurosci. / Multiple mechanisms for the potentiation of AMPA receptor-mediated transmission by α-Ca2+/calmodulin-dependent protein kinase II by Poncer, (2002)
10.1126/science.1103944
10.1523/JNEUROSCI.21-19-07506.2001 / J. Neurosci. / Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway by Sans, (2001)
10.1126/science.284.5421.1811
10.1016/S0092-8674(01)00321-X
10.1126/science.275.5296.73
10.1016/0165-0270(91)90128-M
10.1126/science.1079886
10.1038/80614
10.1016/j.neuron.2005.04.037

Dates

Type	When
Created	18 years, 11 months ago (Sept. 15, 2006, 8:55 p.m.)
Deposited	3 years, 9 months ago (Nov. 11, 2021, 9:34 a.m.)
Indexed	1 year, 7 months ago (Jan. 16, 2024, 9:02 a.m.)
Issued	18 years, 11 months ago (Sept. 1, 2006)
Published	18 years, 11 months ago (Sept. 1, 2006)
Published Online	18 years, 11 months ago (Sept. 15, 2006)
Published Print	18 years, 11 months ago (Sept. 1, 2006)

Funders 0

None

BibTeX

@article{Boehm_2006, title={Two mutations preventing PDZ–protein interactions of GluR1 have opposite effects on synaptic plasticity}, volume={13}, ISSN={1549-5485}, url={http://dx.doi.org/10.1101/lm.253506}, DOI={10.1101/lm.253506}, number={5}, journal={Learning & Memory}, publisher={Cold Spring Harbor Laboratory}, author={Boehm, Jannic and Ehrlich, Ingrid and Hsieh, Helen and Malinow, Roberto}, year={2006}, month=sep, pages={562–565} }

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