DOI: 10.1101/gad.866801. The <i>Arabidopsis HOS1</i> gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold-regulated nucleo

The Arabidopsis HOS1 gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold-regulated nucleo–cytoplasmic partitioning

10.1101/gad.866801

Crossref journal-article

Cold Spring Harbor Laboratory

Genes & Development (246)

Abstract

Low temperature is one of the most important environmental stimuli that control gene transcription programs and development in plants. InArabidopsis thaliana, the HOS1 locus is a key negative regulator of low temperature-responsive gene transcription. The recessive hos1 mutation causes enhanced induction of theCBF transcription factors by low temperature as well as of their downstream cold-responsive genes. The hos1 mutant plants flower early, and this correlates with a low level of Flowering Locus C gene expression. The HOS1 gene was isolated through positional cloning. HOS1 encodes a novel protein with a RING finger motif near the amino terminus. HOS1 is ubiquitously expressed in all plant tissues. HOS1–GFP translational fusion studies reveal that HOS1 protein resides in the cytoplasm at normal growth temperatures. However, in response to low temperature treatments, HOS1 accumulates in the nucleus. Ectopic expression of HOS1 in wild-type plants causes cosuppression of HOS1 expression and mimics the hos1 mutant phenotypes.

Bibliography

Lee, H., Xiong, L., Gong, Z., Ishitani, M., Stevenson, B., & Zhu, J.-K. (2001). The Arabidopsis HOS1 gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold-regulated nucleoâcytoplasmic partitioning. Genes & Development, 15(7), 912â924.

Authors 6

Hojoung Lee (first)
Liming Xiong (additional)
Zhizhong Gong (additional)
Manabu Ishitani (additional)
Becky Stevenson (additional)
Jian-Kang Zhu (additional)

References 48 Referenced 337

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Dates

Type	When
Created	23 years ago (July 26, 2002, 8 p.m.)
Deposited	3 years, 9 months ago (Nov. 15, 2021, 10:36 a.m.)
Indexed	3 days, 2 hours ago (Aug. 22, 2025, 12:45 a.m.)
Issued	24 years, 4 months ago (April 1, 2001)
Published	24 years, 4 months ago (April 1, 2001)
Published Online	24 years, 4 months ago (April 1, 2001)
Published Print	24 years, 4 months ago (April 1, 2001)

Funders 0

None

BibTeX

@article{Lee_2001, title={The Arabidopsis HOS1 gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold-regulated nucleo–cytoplasmic partitioning}, volume={15}, ISSN={1549-5477}, url={http://dx.doi.org/10.1101/gad.866801}, DOI={10.1101/gad.866801}, number={7}, journal={Genes & Development}, publisher={Cold Spring Harbor Laboratory}, author={Lee, Hojoung and Xiong, Liming and Gong, Zhizhong and Ishitani, Manabu and Stevenson, Becky and Zhu, Jian-Kang}, year={2001}, month=apr, pages={912–924} }

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