DOI: 10.1101/gad.7.2.173. Synergism in transcriptional activation: a kinetic view.

Synergism in transcriptional activation: a kinetic view.

10.1101/gad.7.2.173

Crossref journal-article

Cold Spring Harbor Laboratory

Genes & Development (246)

Abstract

Bibliography

Herschlag, D., & Johnson, F. B. (1993). Synergism in transcriptional activation: a kinetic view. Genes & Development, 7(2), 173â179.

Authors 2

D Herschlag (first)
F B Johnson (additional)

References 53 Referenced 154

10.1016/S0021-9258(18)92939-X / J. Biol. Chem. / Promoter-dependent phosphorylation of RNA polymerase II by a template-bound kinase. (1991)
{'key': '2021111418072024000_7.2.173.2', 'first-page': '3635', 'article-title': 'A downstream-element-binding factor facilitates assembly of a functional preinitiation complex at the simian virus 40 major late promoter.', 'volume': '10', 'year': '1990', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / A downstream-element-binding factor facilitates assembly of a functional preinitiation complex at the simian virus 40 major late promoter. (1990)
10.1016/S0021-9258(19)75926-2 / J. Biol. Chem. / Transcription initiation by RNA polymerase II in vitro. (1987)
10.1016/S0021-9258(18)83292-6 / J. Biol. Chem. / Factors involved in specific transcription by mammalian RNA polymerase II. Role of factors IID and MLTF in transciption from the Adenovirus major late and IVa2 promoters. (1989)
10.1038/345361a0
10.1021/bi00685a029
10.1016/S0021-9258(18)55182-6 / J. Biol. Chem. / Initiation of eukaryotic messenger RNA synthesis. (1991)
10.1016/0092-8674(89)90393-0
10.1038/355219a0
Fersht, A.M. 1985. Enzyme structure and mechanism, 2nd ed., pp. 117–120. Freeman, New York.
10.1016/0092-8674(88)90109-2
10.1126/science.1445600
10.1073/pnas.85.2.382
{'key': '2021111418072024000_7.2.173.14', 'first-page': '153', 'article-title': 'Messenger RNA splicing in yeast: Clues to why the spliceosome is a ribonucleoprotein.', 'volume': '253', 'year': '1991', 'journal-title': 'Science'} / Science / Messenger RNA splicing in yeast: Clues to why the spliceosome is a ribonucleoprotein. (1991)
10.1016/0092-8674(89)90580-1
10.1016/S0021-9258(17)39577-7 / J. Biol. Chem. / Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. (1985)
10.1016/S0021-9258(18)61372-9 / J. Biol. Chem. / Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. (1987)
10.1073/pnas.71.10.4135
10.1016/0092-8674(88)90118-3
10.1016/0092-8674(92)90162-6
10.1038/351588a0
10.1016/0092-8674(92)90172-9
10.1073/pnas.87.12.4732
10.1101/gad.6.11.2177
10.1016/S0021-9258(19)39847-3 / J. Biol. Chem. / Assembly and disassembly of the Drosophila RNA Polymerase II complex during transcription. (1990)
10.1101/gad.4.11.1899
10.1016/0092-8674(91)90354-2
10.1016/S0092-8674(88)90189-4
Laidler, K.J. 1978. Physical Chemistry with Biological Applications, pp. 391–398. Benjamin/Cummings Menlo Park, CA.
10.1016/S0021-9258(19)38281-X / J. Biol. Chem. / Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription. (1990)
10.1016/0092-8674(91)90467-D
10.1016/0092-8674(91)90321-O
10.1038/345359a0
10.1038/353569a0
10.1038/358641a0
{'key': '2021111418072024000_7.2.173.36', 'first-page': '6335', 'article-title': 'Factors involved in specific transcription by mammalian RNA polymerase II: Role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.', 'volume': '10', 'year': '1990', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / Factors involved in specific transcription by mammalian RNA polymerase II: Role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex. (1990)
10.1002/j.1460-2075.1987.tb02706.x / EMBO J. / The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element. (1987)
10.1016/0092-8674(91)90530-C
10.1038/358620a0
10.1038/335683a0
{'key': '2021111418072024000_7.2.173.41', 'first-page': '3299', 'article-title': 'Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor.', 'volume': '9', 'year': '1989', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor. (1989)
10.1038/345783a0
10.1016/0968-0004(88)90047-3
10.1084/jem.175.3.637
10.1126/science.3413495
10.1126/science.1310361
10.1101/gad.6.9.1716
10.1002/j.1460-2075.1992.tb05282.x / EMBO ]. / The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes. (1992)
10.1002/j.1460-2075.1990.tb08239.x / EMBO J. / An upstream transcription factor, USF (MLTF) facilitates the formation of preinitiation complexes during in vitro chromatin assembly. (1990)
10.1016/0092-8674(91)90242-Q
10.1016/0968-0004(92)90320-9
10.1016/0955-0674(92)90016-6
{'key': '2021111418072024000_7.2.173.53', 'first-page': '455', 'article-title': 'Serum response factor affects preinitiation complex formation by TFIID in vitro.', 'volume': '3', 'year': '1991', 'journal-title': 'New Biol.'} / New Biol. / Serum response factor affects preinitiation complex formation by TFIID in vitro. (1991)

Dates

Type	When
Created	18 years, 2 months ago (June 5, 2007, 5:15 p.m.)
Deposited	3 years, 9 months ago (Nov. 14, 2021, 9:08 p.m.)
Indexed	4 days, 19 hours ago (Aug. 28, 2025, 8:20 a.m.)
Issued	32 years, 7 months ago (Feb. 1, 1993)
Published	32 years, 7 months ago (Feb. 1, 1993)
Published Online	32 years, 7 months ago (Feb. 1, 1993)
Published Print	32 years, 7 months ago (Feb. 1, 1993)

Funders 0

None

BibTeX

@article{Herschlag_1993, title={Synergism in transcriptional activation: a kinetic view.}, volume={7}, ISSN={1549-5477}, url={http://dx.doi.org/10.1101/gad.7.2.173}, DOI={10.1101/gad.7.2.173}, number={2}, journal={Genes & Development}, publisher={Cold Spring Harbor Laboratory}, author={Herschlag, D and Johnson, F B}, year={1993}, month=feb, pages={173–179} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        28
      ]
    ],
    "date-time": "2025-08-28T12:20:41Z",
    "timestamp": 1756383641905
  },
  "reference-count": 53,
  "publisher": "Cold Spring Harbor Laboratory",
  "issue": "2",
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1993,
        2
      ]
    ]
  },
  "abstract": "<jats:p />",
  "DOI": "10.1101/gad.7.2.173",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2007,
        6,
        5
      ]
    ],
    "date-time": "2007-06-05T21:15:46Z",
    "timestamp": 1181078146000
  },
  "page": "173-179",
  "source": "Crossref",
  "is-referenced-by-count": 154,
  "title": "Synergism in transcriptional activation: a kinetic view.",
  "prefix": "10.1101",
  "volume": "7",
  "author": [
    {
      "given": "D",
      "family": "Herschlag",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "F B",
      "family": "Johnson",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "246",
  "published-online": {
    "date-parts": [
      [
        1993,
        2,
        1
      ]
    ]
  },
  "reference": [
    {
      "key": "2021111418072024000_7.2.173.1",
      "doi-asserted-by": "crossref",
      "first-page": "8055",
      "DOI": "10.1016/S0021-9258(18)92939-X",
      "article-title": "Promoter-dependent phosphorylation of RNA polymerase II by a template-bound kinase.",
      "volume": "266",
      "year": "1991",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.2",
      "first-page": "3635",
      "article-title": "A downstream-element-binding factor facilitates assembly of a functional preinitiation complex at the simian virus 40 major late promoter.",
      "volume": "10",
      "year": "1990",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "2021111418072024000_7.2.173.3",
      "doi-asserted-by": "crossref",
      "first-page": "298",
      "DOI": "10.1016/S0021-9258(19)75926-2",
      "article-title": "Transcription initiation by RNA polymerase II in vitro.",
      "volume": "262",
      "year": "1987",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.4",
      "doi-asserted-by": "crossref",
      "first-page": "7704",
      "DOI": "10.1016/S0021-9258(18)83292-6",
      "article-title": "Factors involved in specific transcription by mammalian RNA polymerase II. Role of factors IID and MLTF in transciption from the Adenovirus major late and IVa2 promoters.",
      "volume": "264",
      "year": "1989",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.5",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/345361a0"
    },
    {
      "key": "2021111418072024000_7.2.173.6",
      "doi-asserted-by": "publisher",
      "DOI": "10.1021/bi00685a029"
    },
    {
      "key": "2021111418072024000_7.2.173.7",
      "doi-asserted-by": "crossref",
      "first-page": "17721",
      "DOI": "10.1016/S0021-9258(18)55182-6",
      "article-title": "Initiation of eukaryotic messenger RNA synthesis.",
      "volume": "266",
      "year": "1991",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.8",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(89)90393-0"
    },
    {
      "key": "2021111418072024000_7.2.173.9",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/355219a0"
    },
    {
      "key": "2021111418072024000_7.2.173.10",
      "unstructured": "Fersht, A.M. 1985. Enzyme structure and mechanism, 2nd ed., pp. 117\u2013120. Freeman, New York."
    },
    {
      "key": "2021111418072024000_7.2.173.11",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(88)90109-2"
    },
    {
      "key": "2021111418072024000_7.2.173.12",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.1445600"
    },
    {
      "key": "2021111418072024000_7.2.173.13",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.85.2.382"
    },
    {
      "key": "2021111418072024000_7.2.173.14",
      "first-page": "153",
      "article-title": "Messenger RNA splicing in yeast: Clues to why the spliceosome is a ribonucleoprotein.",
      "volume": "253",
      "year": "1991",
      "journal-title": "Science"
    },
    {
      "key": "2021111418072024000_7.2.173.15",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(89)90580-1"
    },
    {
      "key": "2021111418072024000_7.2.173.16",
      "doi-asserted-by": "crossref",
      "first-page": "8163",
      "DOI": "10.1016/S0021-9258(17)39577-7",
      "article-title": "Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.",
      "volume": "260",
      "year": "1985",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.17",
      "doi-asserted-by": "crossref",
      "first-page": "3452",
      "DOI": "10.1016/S0021-9258(18)61372-9",
      "article-title": "Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract.",
      "volume": "262",
      "year": "1987",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.18",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.71.10.4135"
    },
    {
      "key": "2021111418072024000_7.2.173.19",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(88)90118-3"
    },
    {
      "key": "2021111418072024000_7.2.173.20",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(92)90162-6"
    },
    {
      "key": "2021111418072024000_7.2.173.21",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/351588a0"
    },
    {
      "key": "2021111418072024000_7.2.173.22",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(92)90172-9"
    },
    {
      "key": "2021111418072024000_7.2.173.23",
      "doi-asserted-by": "publisher",
      "DOI": "10.1073/pnas.87.12.4732"
    },
    {
      "key": "2021111418072024000_7.2.173.24",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.6.11.2177"
    },
    {
      "key": "2021111418072024000_7.2.173.25",
      "doi-asserted-by": "crossref",
      "first-page": "2624",
      "DOI": "10.1016/S0021-9258(19)39847-3",
      "article-title": "Assembly and disassembly of the Drosophila RNA Polymerase II complex during transcription.",
      "volume": "265",
      "year": "1990",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.26",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.4.11.1899"
    },
    {
      "key": "2021111418072024000_7.2.173.27",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(91)90354-2"
    },
    {
      "key": "2021111418072024000_7.2.173.28",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0092-8674(88)90189-4"
    },
    {
      "key": "2021111418072024000_7.2.173.29",
      "unstructured": "Laidler, K.J. 1978. Physical Chemistry with Biological Applications, pp. 391\u2013398. Benjamin/Cummings Menlo Park, CA."
    },
    {
      "key": "2021111418072024000_7.2.173.30",
      "doi-asserted-by": "crossref",
      "first-page": "13165",
      "DOI": "10.1016/S0021-9258(19)38281-X",
      "article-title": "Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription.",
      "volume": "265",
      "year": "1990",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "2021111418072024000_7.2.173.31",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(91)90467-D"
    },
    {
      "key": "2021111418072024000_7.2.173.32",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(91)90321-O"
    },
    {
      "key": "2021111418072024000_7.2.173.33",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/345359a0"
    },
    {
      "key": "2021111418072024000_7.2.173.34",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/353569a0"
    },
    {
      "key": "2021111418072024000_7.2.173.35",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/358641a0"
    },
    {
      "key": "2021111418072024000_7.2.173.36",
      "first-page": "6335",
      "article-title": "Factors involved in specific transcription by mammalian RNA polymerase II: Role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.",
      "volume": "10",
      "year": "1990",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "2021111418072024000_7.2.173.37",
      "doi-asserted-by": "crossref",
      "first-page": "3719",
      "DOI": "10.1002/j.1460-2075.1987.tb02706.x",
      "article-title": "The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element.",
      "volume": "6",
      "year": "1987",
      "journal-title": "EMBO J."
    },
    {
      "key": "2021111418072024000_7.2.173.38",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(91)90530-C"
    },
    {
      "key": "2021111418072024000_7.2.173.39",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/358620a0"
    },
    {
      "key": "2021111418072024000_7.2.173.40",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/335683a0"
    },
    {
      "key": "2021111418072024000_7.2.173.41",
      "first-page": "3299",
      "article-title": "Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor.",
      "volume": "9",
      "year": "1989",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "2021111418072024000_7.2.173.42",
      "doi-asserted-by": "publisher",
      "DOI": "10.1038/345783a0"
    },
    {
      "key": "2021111418072024000_7.2.173.43",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0968-0004(88)90047-3"
    },
    {
      "key": "2021111418072024000_7.2.173.44",
      "doi-asserted-by": "publisher",
      "DOI": "10.1084/jem.175.3.637"
    },
    {
      "key": "2021111418072024000_7.2.173.45",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.3413495"
    },
    {
      "key": "2021111418072024000_7.2.173.46",
      "doi-asserted-by": "publisher",
      "DOI": "10.1126/science.1310361"
    },
    {
      "key": "2021111418072024000_7.2.173.47",
      "doi-asserted-by": "publisher",
      "DOI": "10.1101/gad.6.9.1716"
    },
    {
      "key": "2021111418072024000_7.2.173.48",
      "doi-asserted-by": "crossref",
      "first-page": "2229",
      "DOI": "10.1002/j.1460-2075.1992.tb05282.x",
      "article-title": "The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes.",
      "volume": "11",
      "year": "1992",
      "journal-title": "EMBO ]."
    },
    {
      "key": "2021111418072024000_7.2.173.49",
      "doi-asserted-by": "crossref",
      "first-page": "1299",
      "DOI": "10.1002/j.1460-2075.1990.tb08239.x",
      "article-title": "An upstream transcription factor, USF (MLTF) facilitates the formation of preinitiation complexes during in vitro chromatin assembly.",
      "volume": "9",
      "year": "1990",
      "journal-title": "EMBO J."
    },
    {
      "key": "2021111418072024000_7.2.173.50",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0092-8674(91)90242-Q"
    },
    {
      "key": "2021111418072024000_7.2.173.51",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0968-0004(92)90320-9"
    },
    {
      "key": "2021111418072024000_7.2.173.52",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/0955-0674(92)90016-6"
    },
    {
      "key": "2021111418072024000_7.2.173.53",
      "first-page": "455",
      "article-title": "Serum response factor affects preinitiation complex formation by TFIID in vitro.",
      "volume": "3",
      "year": "1991",
      "journal-title": "New Biol."
    }
  ],
  "container-title": "Genes &amp; Development",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://syndication.highwire.org/content/doi/10.1101/gad.7.2.173",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        11,
        15
      ]
    ],
    "date-time": "2021-11-15T02:08:09Z",
    "timestamp": 1636942089000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "http://genesdev.cshlp.org/lookup/doi/10.1101/gad.7.2.173"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1993,
        2
      ]
    ]
  },
  "references-count": 53,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          1993,
          2
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1101/gad.7.2.173"
  ],
  "URL": "http://dx.doi.org/10.1101/gad.7.2.173",
  "relation": {},
  "ISSN": [
    "0890-9369",
    "1549-5477"
  ],
  "subject": [],
  "container-title-short": "Genes Dev.",
  "published": {
    "date-parts": [
      [
        1993,
        2
      ]
    ]
  }
}