DOI: 10.1101/gad.5.4.583. Glass encodes a site-specific DNA-binding protein that is regulated in response to positional signals in the developing Drosophila eye.

Glass encodes a site-specific DNA-binding protein that is regulated in response to positional signals in the developing Drosophila eye.

10.1101/gad.5.4.583

Crossref journal-article

Cold Spring Harbor Laboratory

Genes & Development (246)

Abstract

The glass gene encodes a zinc finger protein required for normal photoreceptor cell development in Drosophila. We show that glass transcripts are present in the third-instar eye-imaginal disc starting in the morphogenetic furrow and extending to the posterior margin of the disc; glass protein is detected in the nuclei of all cells in this region. We also show that glass encodes a site-specific DNA-binding protein. A 27-bp glass-binding site can confer glass-dependent expression on a reporter gene in developing photoreceptor cells, the particular subset of glass-expressing cells known to require glass function. This specificity may represent a regulation of glass protein activity after cells are recruited to the photoreceptor cell fate.

Bibliography

Moses, K., & Rubin, G. M. (1991). Glass encodes a site-specific DNA-binding protein that is regulated in response to positional signals in the developing Drosophila eye. Genes & Development, 5(4), 583â593.

Authors 2

K Moses (first)
G M Rubin (additional)

References 50 Referenced 205

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Dates

Type	When
Created	18 years, 2 months ago (June 5, 2007, 5:15 p.m.)
Deposited	3 years, 9 months ago (Nov. 13, 2021, 11:20 p.m.)
Indexed	3 weeks, 1 day ago (Aug. 7, 2025, 4:26 p.m.)
Issued	34 years, 4 months ago (April 1, 1991)
Published	34 years, 4 months ago (April 1, 1991)
Published Online	34 years, 4 months ago (April 1, 1991)
Published Print	34 years, 4 months ago (April 1, 1991)

Funders 0

None

BibTeX

@article{Moses_1991, title={Glass encodes a site-specific DNA-binding protein that is regulated in response to positional signals in the developing Drosophila eye.}, volume={5}, ISSN={1549-5477}, url={http://dx.doi.org/10.1101/gad.5.4.583}, DOI={10.1101/gad.5.4.583}, number={4}, journal={Genes & Development}, publisher={Cold Spring Harbor Laboratory}, author={Moses, K and Rubin, G M}, year={1991}, month=apr, pages={583–593} }

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