DOI: 10.1101/gad.1348805. Lost in translation: the influence of ribosomes on bacterial mRNA decay: Figure 1.

Lost in translation: the influence of ribosomes on bacterial mRNA decay: Figure 1.

10.1101/gad.1348805

Crossref journal-article

Cold Spring Harbor Laboratory

Genes & Development (246)

Abstract

The lifetimes of bacterial mRNAs are strongly affected by their association with ribosomes. Events occurring at any stage during translation, including ribosome binding, polypeptide elongation, or translation termination, can influence the susceptibility of mRNA to ribonuclease attack. Ribosomes usually act as protective barriers that impede mRNA cleavage, but in some instances they can instead trigger the decay of the mRNA to which they are bound or send a signal that leads to widespread mRNA destabilization within a cell. The influence of translation on mRNA decay provides a quality-control mechanism for minimizing the use of poorly or improperly translated mRNAs as templates for the production of abnormal proteins that might be toxic to bacteria.

Bibliography

Deana, A., & Belasco, J. G. (2005). Lost in translation: the influence of ribosomes on bacterial mRNA decay: Figure 1. Genes & Development, 19(21), 2526â2533.

Authors 2

Atilio Deana (first)
Joel G. Belasco (additional)

References 80 Referenced 268

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Dates

Type	When
Created	19 years, 9 months ago (Nov. 1, 2005, 5:25 p.m.)
Deposited	3 years, 9 months ago (Nov. 16, 2021, 11:39 a.m.)
Indexed	1 month, 3 weeks ago (July 1, 2025, 6:46 a.m.)
Issued	19 years, 9 months ago (Nov. 1, 2005)
Published	19 years, 9 months ago (Nov. 1, 2005)
Published Online	19 years, 9 months ago (Nov. 1, 2005)
Published Print	19 years, 9 months ago (Nov. 1, 2005)

Funders 0

None

BibTeX

@article{Deana_2005, title={Lost in translation: the influence of ribosomes on bacterial mRNA decay: Figure 1.}, volume={19}, ISSN={1549-5477}, url={http://dx.doi.org/10.1101/gad.1348805}, DOI={10.1101/gad.1348805}, number={21}, journal={Genes & Development}, publisher={Cold Spring Harbor Laboratory}, author={Deana, Atilio and Belasco, Joel G.}, year={2005}, month=nov, pages={2526–2533} }

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