DOI: 10.1093/hmg/ddl210. Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

10.1093/hmg/ddl210

Crossref journal-article

Oxford University Press (OUP)

Human Molecular Genetics (286)

Bibliography

Ehrnhoefer, D. E., Duennwald, M., Markovic, P., Wacker, J. L., Engemann, S., Roark, M., Legleiter, J., Marsh, J. L., Thompson, L. M., Lindquist, S., Muchowski, P. J., & Wanker, E. E. (2006). Green tea (â)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntingtonâs disease models. Human Molecular Genetics, 15(18), 2743â2751.

Authors 12

Dagmar E. Ehrnhoefer (first)
Martin Duennwald (additional)
Phoebe Markovic (additional)
Jennifer L. Wacker (additional)
Sabine Engemann (additional)
Margaret Roark (additional)
Justin Legleiter (additional)
J. Lawrence Marsh (additional)
Leslie M. Thompson (additional)
Susan Lindquist (additional)
Paul J. Muchowski (additional)
Erich E. Wanker (additional)

References 32 Referenced 337

10.1016/0092-8674(93)90585-E / Cell / A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes by The Huntington's Disease Collaborative Research Group (1993)
10.1016/S0968-0004(03)00168-3 / Trends Biochem. Sci. / The hunt for huntingtin function: interaction partners tell many different stories by Harjes (2003)
{'key': 'key\n\t\t\t\t20171012164354_DDL210C3', 'first-page': '16', 'article-title': 'Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36–39 repeats', 'volume': '59', 'author': 'Rubinsztein', 'year': '1996', 'journal-title': 'Am. J. Hum. Genet.'} / Am. J. Hum. Genet. / Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36–39 repeats by Rubinsztein (1996)
10.1097/00005072-198511000-00003 / J. Neuropathol. Exp. Neurol. / Neuropathological classification of Huntington's disease by Vonsattel (1985)
10.1126/science.277.5334.1990 / Science / Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain by DiFiglia (1997)
10.1016/S0092-8674(00)80623-6 / Cell / Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease by Yamamoto (2000)
10.1212/01.wnl.0000192103.24796.42 / Neurology / Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis by Glabe (2006)
10.1038/nrn1806 / Nat. Rev. Neurosci. / Normal huntingtin function: an alternative approach to Huntington's disease by Cattaneo (2005)
10.1016/j.jmb.2004.07.054 / J. Mol. Biol. / Development of a human light chain variable domain (V(L)) intracellular antibody specific for the amino terminus of huntingtin via yeast surface display by Colby (2004)
10.1073/pnas.110138997 / Proc. Natl Acad. Sci. USA / Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy by Heiser (2000)
10.1038/ng864 / Nat. Genet. / A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila by Kazantsev (2002)
10.1074/jbc.275.14.10437 / J. Biol. Chem. / Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening by Nagai (2000)
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Dates

Type	When
Created	19 years ago (Aug. 7, 2006, 8:13 p.m.)
Deposited	6 years, 4 months ago (April 20, 2019, 11 a.m.)
Indexed	2 weeks, 2 days ago (Aug. 12, 2025, 6:01 p.m.)
Issued	19 years ago (Aug. 7, 2006)
Published	19 years ago (Aug. 7, 2006)
Published Online	19 years ago (Aug. 7, 2006)
Published Print	18 years, 11 months ago (Sept. 15, 2006)

Funders 0

None

BibTeX

@article{Ehrnhoefer_2006, title={Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington’s disease models}, volume={15}, ISSN={0964-6906}, url={http://dx.doi.org/10.1093/hmg/ddl210}, DOI={10.1093/hmg/ddl210}, number={18}, journal={Human Molecular Genetics}, publisher={Oxford University Press (OUP)}, author={Ehrnhoefer, Dagmar E. and Duennwald, Martin and Markovic, Phoebe and Wacker, Jennifer L. and Engemann, Sabine and Roark, Margaret and Legleiter, Justin and Marsh, J. Lawrence and Thompson, Leslie M. and Lindquist, Susan and Muchowski, Paul J. and Wanker, Erich E.}, year={2006}, month=aug, pages={2743–2751} }

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